TKC005454
|
O14746 |
Telomerase reverse transcriptase |
None |
75 |
% |
Inhibition |
TKC014568
|
O14746 |
Telomerase reverse transcriptase |
None |
65 |
% |
Inhibition |
TKC035208
|
O14746 |
Telomerase reverse transcriptase |
None |
65000 |
nM |
IC50 |
TKC066096
|
O14746 |
Telomerase reverse transcriptase |
None |
780 |
nM |
IC50 |
TKC134702
|
O14746 |
Telomerase reverse transcriptase |
None |
4000 |
nM |
IC50 |
TKC007127
|
P00533 |
Epidermal growth factor receptor |
None |
19 |
% |
Inhibition |
TKC025462
|
P00533 |
Epidermal growth factor receptor |
None |
>200 |
ug.mL-1 |
IC50 |
TKC025466
|
P00533 |
Epidermal growth factor receptor |
None |
>200 |
ug.mL-1 |
IC50 |
TKC025475
|
P00533 |
Epidermal growth factor receptor |
None |
197 |
ug.mL-1 |
IC50 |
TKC071640
|
P00533 |
Epidermal growth factor receptor |
None |
>20000 |
nM |
IC50 |
TKC076041
|
P00533 |
Epidermal growth factor receptor |
None |
75 |
% |
Inhibition |
TKC077689
|
P00533 |
Epidermal growth factor receptor |
None |
>20000 |
nM |
IC50 |
TKC106319
|
P00533 |
Epidermal growth factor receptor |
None |
56 |
nM |
IC50 |
TKC108557
|
P00533 |
Epidermal growth factor receptor |
None |
0.82 |
nM |
Kd |
TKC151761
|
P00533 |
Epidermal growth factor receptor |
None |
>10000 |
nM |
IC50 |
TKC200866
|
P00533 |
Epidermal growth factor receptor |
None |
>10000 |
nM |
IC50 |
TKC013753
|
P03372 |
Estrogen receptor |
None |
8913 |
nM |
Potency |
TKC019072
|
P03372 |
Estrogen receptor |
None |
78 |
% |
Activity |
TKC022931
|
P03372 |
Estrogen receptor |
None |
1995 |
nM |
Potency |
TKC022961
|
P03372 |
Estrogen receptor |
None |
54 |
% |
Activity |
TKC028029
|
P03372 |
Estrogen receptor |
None |
0 |
% |
Activity |
TKC028034
|
P03372 |
Estrogen receptor |
None |
<0 |
% |
Activity |
TKC028037
|
P03372 |
Estrogen receptor |
None |
1 |
% |
Activity |
TKC028038
|
P03372 |
Estrogen receptor |
None |
<0 |
% |
Activity |
TKC028041
|
P03372 |
Estrogen receptor |
None |
<0 |
% |
Activity |
TKC034016
|
P03372 |
Estrogen receptor |
None |
51 |
% |
Activity |
TKC034337
|
P03372 |
Estrogen receptor |
None |
2800000 |
nM |
IC50 |
TKC034640
|
P03372 |
Estrogen receptor |
None |
>1000000 |
nM |
Ki |
TKC035208
|
P03372 |
Estrogen receptor |
None |
39 |
% |
Activity |
TKC035272
|
P03372 |
Estrogen receptor |
None |
2551 |
nM |
IC50 |
TKC035462
|
P03372 |
Estrogen receptor |
None |
42 |
% |
Activity |
TKC066169
|
P03372 |
Estrogen receptor |
None |
39811 |
nM |
Potency |
TKC075769
|
P03372 |
Estrogen receptor |
None |
251 |
nM |
Potency |
TKC079320
|
P03372 |
Estrogen receptor |
None |
<0 |
% |
Activity |
TKC079321
|
P03372 |
Estrogen receptor |
None |
<0 |
% |
Activity |
TKC087664
|
P03372 |
Estrogen receptor |
None |
3162 |
nM |
Potency |
TKC087988
|
P03372 |
Estrogen receptor |
None |
631 |
nM |
Potency |
TKC087991
|
P03372 |
Estrogen receptor |
None |
4467 |
nM |
Potency |
TKC092297
|
P03372 |
Estrogen receptor |
None |
15849 |
nM |
Potency |
TKC092348
|
P03372 |
Estrogen receptor |
None |
8913 |
nM |
Potency |
TKC096012
|
P03372 |
Estrogen receptor |
None |
126 |
nM |
Potency |
TKC100644
|
P03372 |
Estrogen receptor |
None |
31623 |
nM |
Potency |
TKC101365
|
P03372 |
Estrogen receptor |
None |
12570 |
nM |
EC50 |
TKC102448
|
P03372 |
Estrogen receptor |
None |
2550 |
nM |
EC50 |
TKC107086
|
P03372 |
Estrogen receptor |
None |
8913 |
nM |
Potency |
TKC107735
|
P03372 |
Estrogen receptor |
None |
50119 |
nM |
Potency |
TKC111727
|
P03372 |
Estrogen receptor |
None |
0 |
nM |
Ki |
TKC111738
|
P03372 |
Estrogen receptor |
None |
1 |
nM |
EC50 |
TKC111738
|
P03372 |
Estrogen receptor |
None |
166 |
nM |
IC50 |
TKC111738
|
P03372 |
Estrogen receptor |
None |
210 |
nM |
IC50 |
TKC111738
|
P03372 |
Estrogen receptor |
None |
96 |
nM |
IC50 |
TKC112923
|
P03372 |
Estrogen receptor |
None |
26 |
nM |
EC50 |
TKC115268
|
P03372 |
Estrogen receptor |
None |
15849 |
nM |
Potency |
TKC129821
|
P03372 |
Estrogen receptor |
None |
70 |
% |
Activity |
TKC151345
|
P03372 |
Estrogen receptor |
None |
35 |
% |
Activity |
TKC151713
|
P03372 |
Estrogen receptor |
None |
40 |
% |
Activity |
TKC151765
|
P03372 |
Estrogen receptor |
None |
81 |
% |
Activity |
TKC206549
|
P03372 |
Estrogen receptor |
None |
3548 |
nM |
Potency |
TKC206608
|
P03372 |
Estrogen receptor |
None |
8170 |
nM |
EC50 |
TKC206652
|
P03372 |
Estrogen receptor |
None |
112 |
nM |
Potency |
TKC206725
|
P03372 |
Estrogen receptor |
None |
8 |
nM |
Ki |
TKC206726
|
P03372 |
Estrogen receptor |
None |
72 |
nM |
EC50 |
TKC206759
|
P03372 |
Estrogen receptor |
None |
>10000 |
nM |
IC50 |
TKC206759
|
P03372 |
Estrogen receptor |
None |
>10000 |
nM |
IC50 |
TKC206760
|
P03372 |
Estrogen receptor |
None |
25119 |
nM |
Potency |
TKC206764
|
P03372 |
Estrogen receptor |
None |
0 |
% |
RBA |
TKC206770
|
P03372 |
Estrogen receptor |
None |
5012 |
nM |
Potency |
TKC206779
|
P03372 |
Estrogen receptor |
None |
6310 |
nM |
Potency |
TKC206812
|
P03372 |
Estrogen receptor |
None |
62000 |
nM |
IC50 |
TKC206812
|
P03372 |
Estrogen receptor |
None |
39811 |
nM |
Potency |
TKC206816
|
P03372 |
Estrogen receptor |
None |
>1000 |
nM |
IC50 |
TKC206816
|
P03372 |
Estrogen receptor |
None |
>1000 |
nM |
IC50 |
TKC020117
|
P03956 |
Interstitial collagenase |
None |
95 |
% |
Inhibition |
TKC025462
|
P04626 |
Receptor tyrosine-protein kinase erbB-2 |
None |
>200 |
ug.mL-1 |
IC50 |
TKC025466
|
P04626 |
Receptor tyrosine-protein kinase erbB-2 |
None |
>200 |
ug.mL-1 |
IC50 |
TKC025475
|
P04626 |
Receptor tyrosine-protein kinase erbB-2 |
None |
125 |
ug.mL-1 |
IC50 |
TKC026211
|
P04626 |
Receptor tyrosine-protein kinase erbB-2 |
None |
6 |
ug.mL-1 |
IC50 |
TKC026214
|
P04626 |
Receptor tyrosine-protein kinase erbB-2 |
None |
8 |
ug.mL-1 |
IC50 |
TKC026217
|
P04626 |
Receptor tyrosine-protein kinase erbB-2 |
None |
4 |
ug.mL-1 |
IC50 |
TKC026229
|
P04626 |
Receptor tyrosine-protein kinase erbB-2 |
None |
8 |
ug.mL-1 |
IC50 |
TKC012971
|
P04637 |
Cellular tumor antigen p53 |
None |
15849 |
nM |
Potency |
TKC013753
|
P04637 |
Cellular tumor antigen p53 |
None |
13 |
nM |
Potency |
TKC014568
|
P04637 |
Cellular tumor antigen p53 |
None |
2512 |
nM |
Potency |
TKC016418
|
P04637 |
Cellular tumor antigen p53 |
None |
15849 |
nM |
Potency |
TKC018710
|
P04637 |
Cellular tumor antigen p53 |
None |
5 |
nM |
Potency |
TKC020116
|
P04637 |
Cellular tumor antigen p53 |
None |
1585 |
nM |
Potency |
TKC020117
|
P04637 |
Cellular tumor antigen p53 |
None |
12589 |
nM |
Potency |
TKC020732
|
P04637 |
Cellular tumor antigen p53 |
None |
3162 |
nM |
Potency |
TKC022945
|
P04637 |
Cellular tumor antigen p53 |
None |
10000 |
nM |
Potency |
TKC032619
|
P04637 |
Cellular tumor antigen p53 |
None |
15849 |
nM |
Potency |
TKC034083
|
P04637 |
Cellular tumor antigen p53 |
None |
31623 |
nM |
Potency |
TKC035272
|
P04637 |
Cellular tumor antigen p53 |
None |
12589 |
nM |
Potency |
TKC039869
|
P04637 |
Cellular tumor antigen p53 |
None |
25119 |
nM |
Potency |
TKC052854
|
P04637 |
Cellular tumor antigen p53 |
None |
25119 |
nM |
Potency |
TKC062321
|
P04637 |
Cellular tumor antigen p53 |
None |
10000 |
nM |
Potency |
TKC075769
|
P04637 |
Cellular tumor antigen p53 |
None |
159 |
nM |
Potency |
TKC084075
|
P04637 |
Cellular tumor antigen p53 |
None |
8 |
nM |
Potency |
TKC091895
|
P04637 |
Cellular tumor antigen p53 |
None |
50119 |
nM |
Potency |
TKC092297
|
P04637 |
Cellular tumor antigen p53 |
None |
15849 |
nM |
Potency |
TKC095493
|
P04637 |
Cellular tumor antigen p53 |
None |
3162 |
nM |
Potency |
TKC100636
|
P04637 |
Cellular tumor antigen p53 |
None |
1585 |
nM |
Potency |
TKC100701
|
P04637 |
Cellular tumor antigen p53 |
None |
10000 |
nM |
Potency |
TKC101020
|
P04637 |
Cellular tumor antigen p53 |
None |
12589 |
nM |
Potency |
TKC101618
|
P04637 |
Cellular tumor antigen p53 |
None |
12589 |
nM |
Potency |
TKC102204
|
P04637 |
Cellular tumor antigen p53 |
None |
31623 |
nM |
Potency |
TKC102540
|
P04637 |
Cellular tumor antigen p53 |
None |
31623 |
nM |
Potency |
TKC103149
|
P04637 |
Cellular tumor antigen p53 |
None |
12589 |
nM |
Potency |
TKC103210
|
P04637 |
Cellular tumor antigen p53 |
None |
40 |
nM |
Potency |
TKC103257
|
P04637 |
Cellular tumor antigen p53 |
None |
10000 |
nM |
Potency |
TKC103736
|
P04637 |
Cellular tumor antigen p53 |
None |
2512 |
nM |
Potency |
TKC104070
|
P04637 |
Cellular tumor antigen p53 |
None |
63 |
nM |
Potency |
TKC104071
|
P04637 |
Cellular tumor antigen p53 |
None |
50 |
nM |
Potency |
TKC104072
|
P04637 |
Cellular tumor antigen p53 |
None |
126 |
nM |
Potency |
TKC104073
|
P04637 |
Cellular tumor antigen p53 |
None |
63 |
nM |
Potency |
TKC104114
|
P04637 |
Cellular tumor antigen p53 |
None |
79 |
nM |
Potency |
TKC105153
|
P04637 |
Cellular tumor antigen p53 |
None |
5012 |
nM |
Potency |
TKC105168
|
P04637 |
Cellular tumor antigen p53 |
None |
12589 |
nM |
Potency |
TKC105360
|
P04637 |
Cellular tumor antigen p53 |
None |
15849 |
nM |
Potency |
TKC105424
|
P04637 |
Cellular tumor antigen p53 |
None |
25119 |
nM |
Potency |
TKC105784
|
P04637 |
Cellular tumor antigen p53 |
None |
25119 |
nM |
Potency |
TKC105891
|
P04637 |
Cellular tumor antigen p53 |
None |
10000 |
nM |
Potency |
TKC106232
|
P04637 |
Cellular tumor antigen p53 |
None |
15849 |
nM |
Potency |
TKC107086
|
P04637 |
Cellular tumor antigen p53 |
None |
12589 |
nM |
Potency |
TKC107104
|
P04637 |
Cellular tumor antigen p53 |
None |
12589 |
nM |
Potency |
TKC107201
|
P04637 |
Cellular tumor antigen p53 |
None |
19953 |
nM |
Potency |
TKC107332
|
P04637 |
Cellular tumor antigen p53 |
None |
10000 |
nM |
Potency |
TKC107525
|
P04637 |
Cellular tumor antigen p53 |
None |
31623 |
nM |
Potency |
TKC107627
|
P04637 |
Cellular tumor antigen p53 |
None |
25119 |
nM |
Potency |
TKC107818
|
P04637 |
Cellular tumor antigen p53 |
None |
12589 |
nM |
Potency |
TKC108536
|
P04637 |
Cellular tumor antigen p53 |
None |
5 |
nM |
Potency |
TKC108732
|
P04637 |
Cellular tumor antigen p53 |
None |
19953 |
nM |
Potency |
TKC109484
|
P04637 |
Cellular tumor antigen p53 |
None |
20 |
nM |
Potency |
TKC109519
|
P04637 |
Cellular tumor antigen p53 |
None |
10000 |
nM |
Potency |
TKC109561
|
P04637 |
Cellular tumor antigen p53 |
None |
159 |
nM |
Potency |
TKC109569
|
P04637 |
Cellular tumor antigen p53 |
None |
32 |
nM |
Potency |
TKC110010
|
P04637 |
Cellular tumor antigen p53 |
None |
56234 |
nM |
Potency |
TKC112576
|
P04637 |
Cellular tumor antigen p53 |
None |
50 |
nM |
Potency |
TKC112784
|
P04637 |
Cellular tumor antigen p53 |
None |
31623 |
nM |
Potency |
TKC112792
|
P04637 |
Cellular tumor antigen p53 |
None |
25119 |
nM |
Potency |
TKC115268
|
P04637 |
Cellular tumor antigen p53 |
None |
70795 |
nM |
Potency |
TKC117625
|
P04637 |
Cellular tumor antigen p53 |
None |
3162 |
nM |
Potency |
TKC117993
|
P04637 |
Cellular tumor antigen p53 |
None |
501 |
nM |
Potency |
TKC117994
|
P04637 |
Cellular tumor antigen p53 |
None |
40 |
nM |
Potency |
TKC118006
|
P04637 |
Cellular tumor antigen p53 |
None |
100 |
nM |
Potency |
TKC118895
|
P04637 |
Cellular tumor antigen p53 |
None |
31623 |
nM |
Potency |
TKC132609
|
P04637 |
Cellular tumor antigen p53 |
None |
11220 |
nM |
Potency |
TKC134635
|
P04637 |
Cellular tumor antigen p53 |
None |
56234 |
nM |
Potency |
TKC138777
|
P04637 |
Cellular tumor antigen p53 |
None |
15849 |
nM |
Potency |
TKC140757
|
P04637 |
Cellular tumor antigen p53 |
None |
31623 |
nM |
Potency |
TKC147290
|
P04637 |
Cellular tumor antigen p53 |
None |
12589 |
nM |
Potency |
TKC148482
|
P04637 |
Cellular tumor antigen p53 |
None |
19953 |
nM |
Potency |
TKC149827
|
P04637 |
Cellular tumor antigen p53 |
None |
1000 |
nM |
Potency |
TKC150706
|
P04637 |
Cellular tumor antigen p53 |
None |
31623 |
nM |
Potency |
TKC151237
|
P04637 |
Cellular tumor antigen p53 |
None |
35481 |
nM |
Potency |
TKC151303
|
P04637 |
Cellular tumor antigen p53 |
None |
31623 |
nM |
Potency |
TKC151571
|
P04637 |
Cellular tumor antigen p53 |
None |
6310 |
nM |
Potency |
TKC151758
|
P04637 |
Cellular tumor antigen p53 |
None |
19953 |
nM |
Potency |
TKC173955
|
P04637 |
Cellular tumor antigen p53 |
None |
31623 |
nM |
Potency |
TKC206652
|
P04637 |
Cellular tumor antigen p53 |
None |
32 |
nM |
Potency |
TKC206657
|
P04637 |
Cellular tumor antigen p53 |
None |
8 |
nM |
Potency |
TKC206760
|
P04637 |
Cellular tumor antigen p53 |
None |
31623 |
nM |
Potency |
TKC206760
|
P04637 |
Cellular tumor antigen p53 |
None |
15000 |
nM |
Kd |
TKC206812
|
P04637 |
Cellular tumor antigen p53 |
None |
31623 |
nM |
Potency |
TKC206872
|
P04637 |
Cellular tumor antigen p53 |
None |
631 |
nM |
Potency |
TKC206889
|
P04637 |
Cellular tumor antigen p53 |
None |
501 |
nM |
Potency |
TKC206901
|
P04637 |
Cellular tumor antigen p53 |
None |
2512 |
nM |
Potency |
TKC022945
|
P05067 |
Amyloid-beta precursor protein |
None |
23109 |
nM |
Potency |
TKC027272
|
P05067 |
Amyloid-beta precursor protein |
None |
>300000 |
nM |
EC50 |
TKC027273
|
P05067 |
Amyloid-beta precursor protein |
None |
65400 |
nM |
EC50 |
TKC050321
|
P05067 |
Amyloid-beta precursor protein |
None |
100 |
% |
Activity |
TKC050560
|
P05067 |
Amyloid-beta precursor protein |
None |
0 |
% |
Inhibition |
TKC051308
|
P05067 |
Amyloid-beta precursor protein |
None |
0 |
% |
Inhibition |
TKC059731
|
P05067 |
Amyloid-beta precursor protein |
None |
39 |
% |
Activity |
TKC060461
|
P05067 |
Amyloid-beta precursor protein |
None |
65 |
% |
Activity |
TKC077689
|
P05067 |
Amyloid-beta precursor protein |
None |
100 |
% |
Activity |
TKC102625
|
P05067 |
Amyloid-beta precursor protein |
None |
0 |
% |
Inhibition |
TKC111348
|
P05067 |
Amyloid-beta precursor protein |
None |
17 |
% |
Activity |
TKC113610
|
P05067 |
Amyloid-beta precursor protein |
None |
20 |
% |
Activity |
TKC113764
|
P05067 |
Amyloid-beta precursor protein |
None |
71900 |
nM |
IC50 |
TKC113765
|
P05067 |
Amyloid-beta precursor protein |
None |
28000 |
nM |
IC50 |
TKC113766
|
P05067 |
Amyloid-beta precursor protein |
None |
34300 |
nM |
IC50 |
TKC113767
|
P05067 |
Amyloid-beta precursor protein |
None |
55 |
% |
Inhibition |
TKC113768
|
P05067 |
Amyloid-beta precursor protein |
None |
43500 |
nM |
IC50 |
TKC113769
|
P05067 |
Amyloid-beta precursor protein |
None |
1200 |
nM |
IC50 |
TKC118380
|
P05067 |
Amyloid-beta precursor protein |
None |
13400 |
nM |
IC50 |
TKC118381
|
P05067 |
Amyloid-beta precursor protein |
None |
10100 |
nM |
IC50 |
TKC118419
|
P05067 |
Amyloid-beta precursor protein |
None |
231 |
nM |
Potency |
TKC123071
|
P05067 |
Amyloid-beta precursor protein |
None |
20 |
% |
Activity |
TKC150909
|
P05067 |
Amyloid-beta precursor protein |
None |
0 |
% |
Activity |
TKC152398
|
P05067 |
Amyloid-beta precursor protein |
None |
100000 |
nM |
IC50 |
TKC179988
|
P05067 |
Amyloid-beta precursor protein |
None |
8 |
hr |
TIME |
TKC206799
|
P05067 |
Amyloid-beta precursor protein |
None |
95900 |
nM |
IC50 |
TKC012929
|
P05771 |
Protein kinase C beta type |
None |
2 |
nM |
Ki |
TKC055602
|
P05771 |
Protein kinase C beta type |
None |
>150000 |
nM |
IC50 |
TKC075924
|
P05771 |
Protein kinase C beta type |
None |
90 |
% |
Inhibition |
TKC090435
|
P05771 |
Protein kinase C beta type |
None |
0.2 |
nM |
Kd |
TKC103074
|
P05771 |
Protein kinase C beta type |
None |
>150000 |
nM |
IC50 |
TKC104128
|
P05771 |
Protein kinase C beta type |
None |
>150000 |
nM |
IC50 |
TKC104703
|
P05771 |
Protein kinase C beta type |
None |
>150000 |
nM |
IC50 |
TKC105956
|
P05771 |
Protein kinase C beta type |
None |
2 |
nM |
Ki |
TKC123088
|
P05771 |
Protein kinase C beta type |
None |
>150000 |
nM |
IC50 |
TKC151276
|
P05771 |
Protein kinase C beta type |
None |
>150000 |
nM |
IC50 |
TKC151326
|
P05771 |
Protein kinase C beta type |
None |
1 |
nM |
Kd |
TKC151326
|
P05771 |
Protein kinase C beta type |
None |
1.3 |
nM |
Kd |
TKC151326
|
P05771 |
Protein kinase C beta type |
None |
1.3 |
nM |
Kd |
TKC151326
|
P05771 |
Protein kinase C beta type |
None |
1.8 |
nM |
Ki |
TKC151326
|
P05771 |
Protein kinase C beta type |
None |
1.3 |
nM |
Kd |
TKC151326
|
P05771 |
Protein kinase C beta type |
None |
1.3 |
nM |
Kd |
TKC152742
|
P05771 |
Protein kinase C beta type |
None |
>150000 |
nM |
IC50 |
TKC206051
|
P07858 |
Cathepsin B |
None |
103500 |
nM |
IC50 |
TKC009193
|
P08253 |
72 kDa type IV collagenase |
None |
33260 |
nM |
IC50 |
TKC020117
|
P08253 |
72 kDa type IV collagenase |
None |
90 |
% |
Inhibition |
TKC023429
|
P08253 |
72 kDa type IV collagenase |
None |
0 |
ug.mL-1 |
IC50 |
TKC020712
|
P08581 |
Hepatocyte growth factor receptor |
None |
>20000 |
nM |
IC50 |
TKC024886
|
P08581 |
Hepatocyte growth factor receptor |
None |
3120 |
nM |
IC50 |
TKC025690
|
P08581 |
Hepatocyte growth factor receptor |
None |
>100000 |
nM |
IC50 |
TKC033871
|
P08581 |
Hepatocyte growth factor receptor |
None |
50000 |
nM |
IC50 |
TKC082039
|
P08581 |
Hepatocyte growth factor receptor |
None |
5500 |
nM |
IC50 |
TKC115259
|
P08581 |
Hepatocyte growth factor receptor |
None |
34000 |
nM |
IC50 |
TKC115261
|
P08581 |
Hepatocyte growth factor receptor |
None |
47600 |
nM |
IC50 |
TKC115272
|
P08581 |
Hepatocyte growth factor receptor |
None |
>100000 |
nM |
IC50 |
TKC115273
|
P08581 |
Hepatocyte growth factor receptor |
None |
27500 |
nM |
IC50 |
TKC152148
|
P08581 |
Hepatocyte growth factor receptor |
None |
78000 |
nM |
IC50 |
TKC152157
|
P08581 |
Hepatocyte growth factor receptor |
None |
71500 |
nM |
IC50 |
TKC174547
|
P08581 |
Hepatocyte growth factor receptor |
None |
>100000 |
nM |
IC50 |
TKC014892
|
P11387 |
DNA topoisomerase 1 |
None |
3 |
ug.mL-1 |
MIC |
TKC014893
|
P11387 |
DNA topoisomerase 1 |
None |
13 |
ug.mL-1 |
MIC |
TKC017201
|
P11387 |
DNA topoisomerase 1 |
None |
13 |
ug.mL-1 |
MIC |
TKC048122
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC048308
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC048324
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC048330
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC048341
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC049414
|
P11387 |
DNA topoisomerase 1 |
None |
25000 |
nM |
IC50 |
TKC049417
|
P11387 |
DNA topoisomerase 1 |
None |
55000 |
nM |
IC50 |
TKC056419
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC056423
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC056425
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC056427
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC056430
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC058891
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC058895
|
P11387 |
DNA topoisomerase 1 |
None |
48600 |
nM |
IC50 |
TKC058897
|
P11387 |
DNA topoisomerase 1 |
None |
45100 |
nM |
IC50 |
TKC058919
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC058921
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC058935
|
P11387 |
DNA topoisomerase 1 |
None |
109300 |
nM |
IC50 |
TKC058949
|
P11387 |
DNA topoisomerase 1 |
None |
250000 |
nM |
IC50 |
TKC058950
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC058953
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC058979
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC059000
|
P11387 |
DNA topoisomerase 1 |
None |
53700 |
nM |
IC50 |
TKC059030
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC059045
|
P11387 |
DNA topoisomerase 1 |
None |
131700 |
nM |
IC50 |
TKC059148
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC059149
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC059160
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC059165
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC059317
|
P11387 |
DNA topoisomerase 1 |
None |
250000 |
nM |
IC50 |
TKC059337
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC059344
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC059345
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC059425
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC072969
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC072970
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC096715
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC100727
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC103324
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC105545
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC137826
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC137841
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC138033
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC138054
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC143022
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC143033
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC143055
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC143114
|
P11387 |
DNA topoisomerase 1 |
None |
250000 |
nM |
IC50 |
TKC143115
|
P11387 |
DNA topoisomerase 1 |
None |
23800 |
nM |
IC50 |
TKC145932
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC146257
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC147779
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC147805
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC148618
|
P11387 |
DNA topoisomerase 1 |
None |
106000 |
nM |
IC50 |
TKC205544
|
P11387 |
DNA topoisomerase 1 |
None |
30000 |
nM |
IC50 |
TKC205878
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC207002
|
P11387 |
DNA topoisomerase 1 |
None |
>250000 |
nM |
IC50 |
TKC026583
|
P11802 |
Cyclin-dependent kinase 4 |
None |
9 |
ug.mL-1 |
IC50 |
TKC113582
|
P11802 |
Cyclin-dependent kinase 4 |
None |
10 |
ug.mL-1 |
IC50 |
TKC011761
|
P12931 |
Proto-oncogene tyrosine-protein kinase Src |
None |
61 |
% |
Inhibition |
TKC024886
|
P12931 |
Proto-oncogene tyrosine-protein kinase Src |
None |
8620 |
nM |
IC50 |
TKC025690
|
P12931 |
Proto-oncogene tyrosine-protein kinase Src |
None |
19700 |
nM |
IC50 |
TKC115259
|
P12931 |
Proto-oncogene tyrosine-protein kinase Src |
None |
2400 |
nM |
IC50 |
TKC115261
|
P12931 |
Proto-oncogene tyrosine-protein kinase Src |
None |
2240 |
nM |
IC50 |
TKC115272
|
P12931 |
Proto-oncogene tyrosine-protein kinase Src |
None |
>100000 |
nM |
IC50 |
TKC115273
|
P12931 |
Proto-oncogene tyrosine-protein kinase Src |
None |
1480 |
nM |
IC50 |
TKC135974
|
P12931 |
Proto-oncogene tyrosine-protein kinase Src |
None |
35800 |
nM |
IC50 |
TKC151761
|
P12931 |
Proto-oncogene tyrosine-protein kinase Src |
None |
>10000 |
nM |
IC50 |
TKC152148
|
P12931 |
Proto-oncogene tyrosine-protein kinase Src |
None |
1910 |
nM |
IC50 |
TKC152157
|
P12931 |
Proto-oncogene tyrosine-protein kinase Src |
None |
2170 |
nM |
IC50 |
TKC174547
|
P12931 |
Proto-oncogene tyrosine-protein kinase Src |
None |
>100000 |
nM |
IC50 |
TKC200866
|
P12931 |
Proto-oncogene tyrosine-protein kinase Src |
None |
>10000 |
nM |
IC50 |
TKC205544
|
P14416 |
D(2) dopamine receptor |
None |
687 |
nM |
Ki |
TKC205544
|
P14416 |
D(2) dopamine receptor |
None |
280 |
nM |
Ki |
TKC205544
|
P14416 |
D(2) dopamine receptor |
None |
398.1 |
nM |
Ki |
TKC206544
|
P14416 |
D(2) dopamine receptor |
None |
>10000 |
nM |
Ki |
TKC020117
|
P14780 |
Matrix metalloproteinase-9 |
None |
99 |
% |
Inhibition |
TKC023429
|
P14780 |
Matrix metalloproteinase-9 |
None |
1 |
ug.mL-1 |
IC50 |
TKC037777
|
P14780 |
Matrix metalloproteinase-9 |
None |
6 |
ug.mL-1 |
IC50 |
TKC039471
|
P14780 |
Matrix metalloproteinase-9 |
None |
6 |
ug.mL-1 |
IC50 |
TKC006896
|
P14902 |
Indoleamine 2,3-dioxygenase 1 |
None |
7700 |
nM |
IC50 |
TKC014575
|
P14902 |
Indoleamine 2,3-dioxygenase 1 |
None |
4680 |
nM |
IC50 |
TKC024473
|
P14902 |
Indoleamine 2,3-dioxygenase 1 |
None |
10000 |
nM |
IC50 |
TKC024474
|
P14902 |
Indoleamine 2,3-dioxygenase 1 |
None |
11000 |
nM |
IC50 |
TKC104241
|
P14902 |
Indoleamine 2,3-dioxygenase 1 |
None |
0 |
nM |
EC50 |
TKC118419
|
P24941 |
Cyclin-dependent kinase 2 |
None |
95 |
% |
Activity |
TKC206292
|
P24941 |
Cyclin-dependent kinase 2 |
None |
4800 |
nM |
Kd |
TKC022852
|
P26358 |
DNA (cytosine-5)-methyltransferase 1 |
None |
2 |
uM |
Activity |
TKC022854
|
P26358 |
DNA (cytosine-5)-methyltransferase 1 |
None |
55 |
uM |
Activity |
TKC055219
|
P26358 |
DNA (cytosine-5)-methyltransferase 1 |
None |
5930 |
nM |
IC50 |
TKC055219
|
P26358 |
DNA (cytosine-5)-methyltransferase 1 |
None |
5930 |
nM |
IC50 |
TKC001930
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
31623 |
nM |
Potency |
TKC005139
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
4467 |
nM |
Potency |
TKC005313
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
6 |
nM |
Potency |
TKC005454
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
39811 |
nM |
Potency |
TKC008286
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
11220 |
nM |
Potency |
TKC009499
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
11220 |
nM |
Potency |
TKC011384
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
39811 |
nM |
Potency |
TKC011526
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
5 |
nM |
Potency |
TKC011921
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
39811 |
nM |
Potency |
TKC012929
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
891 |
nM |
Potency |
TKC013755
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
6 |
nM |
Potency |
TKC018288
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
7943 |
nM |
Potency |
TKC018339
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
35481 |
nM |
Potency |
TKC019571
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
891 |
nM |
Potency |
TKC019887
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
35481 |
nM |
Potency |
TKC020117
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
14125 |
nM |
Potency |
TKC020459
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
35481 |
nM |
Potency |
TKC020574
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
31623 |
nM |
Potency |
TKC021477
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
7943 |
nM |
Potency |
TKC022945
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
50 |
nM |
Potency |
TKC023619
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
31623 |
nM |
Potency |
TKC025405
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
15849 |
nM |
Potency |
TKC026870
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
3162 |
nM |
Potency |
TKC028718
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
11220 |
nM |
Potency |
TKC029307
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
47444 |
nM |
Potency |
TKC030478
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
18888 |
nM |
Potency |
TKC035029
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
398 |
nM |
Potency |
TKC035272
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
31623 |
nM |
Potency |
TKC035580
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
3 |
nM |
Potency |
TKC036999
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
31623 |
nM |
Potency |
TKC038473
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
447 |
nM |
Potency |
TKC039332
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
5012 |
nM |
Potency |
TKC040026
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
0 |
nM |
Potency |
TKC040829
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
316 |
nM |
Potency |
TKC052854
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
21192 |
nM |
Potency |
TKC053751
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
39811 |
nM |
Potency |
TKC055066
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
70795 |
nM |
Potency |
TKC056469
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
19953 |
nM |
Potency |
TKC056482
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
44668 |
nM |
Potency |
TKC057133
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
35481 |
nM |
Potency |
TKC062333
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
39811 |
nM |
Potency |
TKC063247
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
5 |
nM |
Potency |
TKC066332
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
31623 |
nM |
Potency |
TKC066411
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
5012 |
nM |
Potency |
TKC066631
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
2239 |
nM |
Potency |
TKC073833
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
3 |
nM |
Potency |
TKC075769
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
44668 |
nM |
Potency |
TKC076129
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
7080 |
nM |
Potency |
TKC077689
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
4467 |
nM |
Potency |
TKC080049
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
7943 |
nM |
Potency |
TKC080874
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
44668 |
nM |
Potency |
TKC085168
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
50 |
nM |
Potency |
TKC088230
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
2512 |
nM |
Potency |
TKC088231
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
31623 |
nM |
Potency |
TKC088678
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
316 |
nM |
Potency |
TKC090518
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
19953 |
nM |
Potency |
TKC092297
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
398 |
nM |
Potency |
TKC095442
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
2 |
nM |
Potency |
TKC095645
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
22387 |
nM |
Potency |
TKC097937
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
19953 |
nM |
Potency |
TKC097944
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
14125 |
nM |
Potency |
TKC100524
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
19953 |
nM |
Potency |
TKC100990
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
562 |
nM |
Potency |
TKC102657
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
29935 |
nM |
Potency |
TKC103150
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
31623 |
nM |
Potency |
TKC103159
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
50119 |
nM |
Potency |
TKC103538
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
4 |
nM |
Potency |
TKC104194
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
25119 |
nM |
Potency |
TKC105095
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
28184 |
nM |
Potency |
TKC105168
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
4 |
nM |
Potency |
TKC105226
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
11220 |
nM |
Potency |
TKC105356
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
39811 |
nM |
Potency |
TKC105357
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
35481 |
nM |
Potency |
TKC105378
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
355 |
nM |
Potency |
TKC105710
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
6310 |
nM |
Potency |
TKC105717
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
12589 |
nM |
Potency |
TKC106074
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
40 |
nM |
Potency |
TKC106147
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
1122 |
nM |
Potency |
TKC106537
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
19953 |
nM |
Potency |
TKC106682
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
20 |
nM |
Potency |
TKC107104
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
11220 |
nM |
Potency |
TKC107593
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
1259 |
nM |
Potency |
TKC107830
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
56 |
nM |
Potency |
TKC108060
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
44668 |
nM |
Potency |
TKC108363
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
11220 |
nM |
Potency |
TKC109484
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
3 |
nM |
Potency |
TKC109493
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
1337 |
nM |
Potency |
TKC110002
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
8913 |
nM |
Potency |
TKC112576
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
1413 |
nM |
Potency |
TKC112754
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
794 |
nM |
Potency |
TKC112784
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
3981 |
nM |
Potency |
TKC112813
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
7080 |
nM |
Potency |
TKC113063
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
28184 |
nM |
Potency |
TKC113150
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
1995 |
nM |
Potency |
TKC118131
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
44668 |
nM |
Potency |
TKC118419
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
44668 |
nM |
Potency |
TKC118895
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
14 |
nM |
Potency |
TKC118911
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
112 |
nM |
Potency |
TKC130327
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
251 |
nM |
Potency |
TKC130342
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
17783 |
nM |
Potency |
TKC133919
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
1585 |
nM |
Potency |
TKC141805
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
39811 |
nM |
Potency |
TKC150625
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
9466 |
nM |
Potency |
TKC150706
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
11220 |
nM |
Potency |
TKC151293
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
8913 |
nM |
Potency |
TKC151326
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
13 |
nM |
Potency |
TKC151609
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
39811 |
nM |
Potency |
TKC164433
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
9466 |
nM |
Potency |
TKC169452
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
2239 |
nM |
Potency |
TKC169457
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
2239 |
nM |
Potency |
TKC174441
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
8437 |
nM |
Potency |
TKC202992
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
3 |
nM |
Potency |
TKC206113
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
1778 |
nM |
Potency |
TKC206177
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
2511886 |
nM |
Potency |
TKC206657
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
501 |
nM |
Potency |
TKC206760
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
39811 |
nM |
Potency |
TKC206764
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
12589254 |
nM |
Potency |
TKC206779
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
79 |
nM |
Potency |
TKC206872
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
200 |
nM |
Potency |
TKC207103
|
P27695 |
DNA-(apurinic or apyrimidinic site) endonuclease |
None |
22 |
nM |
Potency |
TKC112785
|
P29317 |
Ephrin type-A receptor 2 |
None |
48978 |
nM |
IC50 |
TKC206760
|
P29317 |
Ephrin type-A receptor 2 |
None |
50000 |
nM |
IC50 |
TKC011761
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
54 |
% |
Inhibition |
TKC016414
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
36 |
% |
Activity |
TKC024886
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
48400 |
nM |
IC50 |
TKC025690
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
>100000 |
nM |
IC50 |
TKC044763
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
100 |
% |
Inhibition |
TKC115259
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
>100000 |
nM |
IC50 |
TKC115261
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
>100000 |
nM |
IC50 |
TKC115272
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
>100000 |
nM |
IC50 |
TKC115273
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
>100000 |
nM |
IC50 |
TKC118419
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
96 |
% |
Inhibition |
TKC152148
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
>100000 |
nM |
IC50 |
TKC152157
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
>100000 |
nM |
IC50 |
TKC174547
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
>100000 |
nM |
IC50 |
TKC206776
|
P31749 |
RAC-alpha serine/threonine-protein kinase |
None |
3 |
uM |
Activity |
TKC205544
|
P35462 |
D(3) dopamine receptor |
None |
2489 |
nM |
Ki |
TKC205544
|
P35462 |
D(3) dopamine receptor |
None |
3981.07 |
nM |
Ki |
TKC206544
|
P35462 |
D(3) dopamine receptor |
None |
>10000 |
nM |
Ki |
TKC206549
|
P35869 |
Aryl hydrocarbon receptor |
None |
17783 |
nM |
Potency |
TKC024886
|
P35968 |
Vascular endothelial growth factor receptor 2 |
None |
4810 |
nM |
IC50 |
TKC025690
|
P35968 |
Vascular endothelial growth factor receptor 2 |
None |
3660 |
nM |
IC50 |
TKC051154
|
P35968 |
Vascular endothelial growth factor receptor 2 |
None |
40 |
% |
Inhibition |
TKC051155
|
P35968 |
Vascular endothelial growth factor receptor 2 |
None |
46 |
% |
Inhibition |
TKC065375
|
P35968 |
Vascular endothelial growth factor receptor 2 |
None |
0 |
% |
Inhibition |
TKC102689
|
P35968 |
Vascular endothelial growth factor receptor 2 |
None |
0 |
% |
Inhibition |
TKC108267
|
P35968 |
Vascular endothelial growth factor receptor 2 |
None |
0 |
% |
Inhibition |
TKC115259
|
P35968 |
Vascular endothelial growth factor receptor 2 |
None |
4950 |
nM |
IC50 |
TKC115261
|
P35968 |
Vascular endothelial growth factor receptor 2 |
None |
4600 |
nM |
IC50 |
TKC115272
|
P35968 |
Vascular endothelial growth factor receptor 2 |
None |
>100000 |
nM |
IC50 |
TKC115273
|
P35968 |
Vascular endothelial growth factor receptor 2 |
None |
4850 |
nM |
IC50 |
TKC146202
|
P35968 |
Vascular endothelial growth factor receptor 2 |
None |
61 |
% |
Inhibition |
TKC152148
|
P35968 |
Vascular endothelial growth factor receptor 2 |
None |
4350 |
nM |
IC50 |
TKC152157
|
P35968 |
Vascular endothelial growth factor receptor 2 |
None |
6010 |
nM |
IC50 |
TKC174547
|
P35968 |
Vascular endothelial growth factor receptor 2 |
None |
>100000 |
nM |
IC50 |
TKC207124
|
P35968 |
Vascular endothelial growth factor receptor 2 |
None |
40400 |
nM |
IC50 |
TKC003060
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>50000 |
nM |
IC50 |
TKC005454
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
4600 |
nM |
IC50 |
TKC016414
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>10000 |
nM |
EC50 |
TKC020636
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
6900 |
nM |
IC50 |
TKC020796
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
22900 |
nM |
IC50 |
TKC020867
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
26 |
% |
Inhibition |
TKC020868
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
31 |
% |
Inhibition |
TKC020869
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
49 |
% |
Inhibition |
TKC022393
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
89500 |
nM |
IC50 |
TKC022771
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>100000 |
nM |
IC50 |
TKC028367
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
4100 |
nM |
IC50 |
TKC030728
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
2 |
% |
Inhibition |
TKC033506
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
2400 |
nM |
IC50 |
TKC033507
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
2300 |
nM |
IC50 |
TKC036334
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
4 |
% |
Inhibition |
TKC038766
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
1 |
% |
Inhibition |
TKC039282
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
2 |
% |
Inhibition |
TKC042554
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
6300 |
nM |
IC50 |
TKC042556
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
110000 |
nM |
IC50 |
TKC044507
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
4 |
% |
Inhibition |
TKC044595
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
4 |
% |
Inhibition |
TKC044621
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
3 |
% |
Inhibition |
TKC044669
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
4 |
% |
Inhibition |
TKC047957
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
17100 |
nM |
IC50 |
TKC047959
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>30000 |
nM |
IC50 |
TKC047961
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>30000 |
nM |
IC50 |
TKC048029
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
270 |
nM |
IC50 |
TKC048030
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
19200 |
nM |
IC50 |
TKC048031
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
590 |
nM |
IC50 |
TKC051029
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
60000 |
nM |
MIC |
TKC060882
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>25000 |
nM |
IC50 |
TKC075769
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
1862 |
nM |
IC50 |
TKC077689
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>50000 |
nM |
IC50 |
TKC078334
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>50000 |
nM |
IC50 |
TKC087623
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>100000 |
nM |
IC50 |
TKC087625
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
7000 |
nM |
IC50 |
TKC093311
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>50000 |
nM |
IC50 |
TKC100739
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>50000 |
nM |
IC50 |
TKC101161
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>50000 |
nM |
IC50 |
TKC103159
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
3000 |
nM |
IC50 |
TKC103189
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
32500 |
nM |
IC50 |
TKC103191
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
24800 |
nM |
IC50 |
TKC105152
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>50000 |
nM |
IC50 |
TKC107659
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
4 |
% |
Inhibition |
TKC108773
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>50000 |
nM |
IC50 |
TKC112576
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
1154 |
nM |
IC50 |
TKC134761
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
48 |
% |
Inhibition |
TKC135961
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
73000 |
nM |
IC50 |
TKC135978
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
14210 |
nM |
IC50 |
TKC136653
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
2 |
% |
Inhibition |
TKC148207
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
15840 |
nM |
IC50 |
TKC149924
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
74 |
% |
Inhibition |
TKC151284
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
14000 |
nM |
IC50 |
TKC156528
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>30000 |
nM |
IC50 |
TKC206318
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
12200 |
nM |
IC50 |
TKC206468
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
46 |
% |
Inhibition |
TKC206627
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
>100000 |
nM |
IC50 |
TKC206646
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
67000 |
nM |
IC50 |
TKC206652
|
P40763 |
Signal transducer and activator of transcription 3 |
None |
700 |
nM |
IC50 |
TKC036497
|
P42574 |
Caspase-3 |
None |
200000 |
nM |
IC50 |
TKC096499
|
P42574 |
Caspase-3 |
None |
50000 |
nM |
IC50 |
TKC025058
|
P48736 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
None |
1000 |
nM |
IC50 |
TKC118419
|
P48736 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
None |
5 |
nM |
IC50 |
TKC118419
|
P48736 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
None |
19 |
nM |
IC50 |
TKC118419
|
P48736 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
None |
55 |
nM |
IC50 |
TKC118419
|
P48736 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
None |
55000 |
nM |
IC50 |
TKC118419
|
P48736 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
None |
89 |
nM |
IC50 |
TKC118419
|
P48736 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
None |
5 |
nM |
IC50 |
TKC118419
|
P48736 |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform |
None |
15 |
nM |
Kd |
TKC087988
|
P49327 |
Fatty acid synthase |
None |
>40 |
% |
Inhibition |
TKC046324
|
P49840 |
Glycogen synthase kinase-3 alpha |
None |
1600 |
nM |
IC50 |
TKC011761
|
P49841 |
Glycogen synthase kinase-3 beta |
None |
20 |
% |
Inhibition |
TKC046098
|
P49841 |
Glycogen synthase kinase-3 beta |
None |
794 |
nM |
IC50 |
TKC046099
|
P49841 |
Glycogen synthase kinase-3 beta |
None |
2300 |
nM |
IC50 |
TKC046324
|
P49841 |
Glycogen synthase kinase-3 beta |
None |
4500 |
nM |
IC50 |
TKC046324
|
P49841 |
Glycogen synthase kinase-3 beta |
None |
1900 |
nM |
IC50 |
TKC118419
|
P49841 |
Glycogen synthase kinase-3 beta |
None |
65 |
% |
Activity |
TKC146056
|
P49841 |
Glycogen synthase kinase-3 beta |
None |
3000 |
nM |
IC50 |
TKC021620
|
P60568 |
Interleukin-2 |
None |
3 |
nM |
Kd |
TKC116180
|
P60568 |
Interleukin-2 |
None |
0 |
nM |
Kd |
TKC151761
|
Q12866 |
Tyrosine-protein kinase Mer |
None |
4900 |
nM |
IC50 |
TKC200866
|
Q12866 |
Tyrosine-protein kinase Mer |
None |
4900 |
nM |
IC50 |
TKC016189
|
Q13315 |
Serine-protein kinase ATM |
None |
19953 |
nM |
Potency |
TKC016371
|
Q13315 |
Serine-protein kinase ATM |
None |
25119 |
nM |
Potency |
TKC029307
|
Q13315 |
Serine-protein kinase ATM |
None |
39811 |
nM |
Potency |
TKC039202
|
Q13315 |
Serine-protein kinase ATM |
None |
3548 |
nM |
Potency |
TKC063474
|
Q13315 |
Serine-protein kinase ATM |
None |
35481 |
nM |
Potency |
TKC066411
|
Q13315 |
Serine-protein kinase ATM |
None |
31623 |
nM |
Potency |
TKC103159
|
Q13315 |
Serine-protein kinase ATM |
None |
19953 |
nM |
Potency |
TKC150598
|
Q13315 |
Serine-protein kinase ATM |
None |
39811 |
nM |
Potency |
TKC151609
|
Q13315 |
Serine-protein kinase ATM |
None |
39811 |
nM |
Potency |
TKC174441
|
Q13315 |
Serine-protein kinase ATM |
None |
412 |
nM |
Potency |
TKC005475
|
Q15910 |
Histone-lysine N-methyltransferase EZH2 |
None |
9600 |
nM |
IC50 |
TKC014568
|
Q15910 |
Histone-lysine N-methyltransferase EZH2 |
None |
8900 |
nM |
IC50 |
TKC005454
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
1360 |
nM |
IC50 |
TKC005475
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
7340 |
nM |
IC50 |
TKC010010
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
>20000 |
nM |
IC50 |
TKC011921
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
1995 |
nM |
Potency |
TKC012261
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
280 |
nM |
IC50 |
TKC012262
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
3180 |
nM |
IC50 |
TKC012971
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
25119 |
nM |
Potency |
TKC014568
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
8510 |
nM |
IC50 |
TKC017189
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
10600 |
nM |
IC50 |
TKC017192
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
1700 |
nM |
IC50 |
TKC017193
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
2300 |
nM |
IC50 |
TKC020116
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
501 |
nM |
Potency |
TKC022945
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
2512 |
nM |
Potency |
TKC023570
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
15800 |
nM |
IC50 |
TKC030239
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
200 |
nM |
Potency |
TKC035272
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
10000 |
nM |
Potency |
TKC037547
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
10 |
% |
Activity |
TKC038977
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
820 |
nM |
IC50 |
TKC045710
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
500 |
nM |
IC50 |
TKC045931
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
2900 |
nM |
IC50 |
TKC045946
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
2900 |
nM |
IC50 |
TKC047694
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
63 |
nM |
IC50 |
TKC047695
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
68 |
nM |
IC50 |
TKC056482
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
>100000 |
nM |
IC50 |
TKC056482
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
>100000 |
nM |
IC50 |
TKC062172
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
15000 |
nM |
IC50 |
TKC062175
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
20000 |
nM |
IC50 |
TKC062182
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
20000 |
nM |
IC50 |
TKC062192
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
20000 |
nM |
IC50 |
TKC062193
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
>30000 |
nM |
IC50 |
TKC065782
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
>30000 |
nM |
IC50 |
TKC081893
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
400 |
nM |
IC50 |
TKC092297
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
39811 |
nM |
Potency |
TKC094057
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
>30000 |
nM |
IC50 |
TKC094058
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
>20000 |
nM |
IC50 |
TKC095493
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
3162 |
nM |
Potency |
TKC096011
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
1 |
nM |
Potency |
TKC096012
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
251 |
nM |
Potency |
TKC100416
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
25119 |
nM |
Potency |
TKC100643
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
12589 |
nM |
Potency |
TKC100990
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
159 |
nM |
Potency |
TKC101618
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
15849 |
nM |
Potency |
TKC102145
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
1259 |
nM |
Potency |
TKC102589
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
8000 |
nM |
EC50 |
TKC103149
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
31623 |
nM |
Potency |
TKC103159
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
270 |
nM |
IC50 |
TKC103433
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
>30000 |
nM |
IC50 |
TKC103494
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
79 |
nM |
Potency |
TKC103496
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
20 |
nM |
Potency |
TKC104070
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
40 |
nM |
Potency |
TKC104071
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
100 |
nM |
Potency |
TKC104114
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
126 |
nM |
Potency |
TKC104664
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
794 |
nM |
Potency |
TKC105037
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
794 |
nM |
Potency |
TKC105510
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
6000 |
nM |
EC50 |
TKC105710
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
12589 |
nM |
Potency |
TKC106426
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
1000 |
nM |
Potency |
TKC106576
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
13000 |
nM |
EC50 |
TKC107086
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
19953 |
nM |
Potency |
TKC109561
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
251 |
nM |
Potency |
TKC110002
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
63 |
nM |
Potency |
TKC110007
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
7943 |
nM |
Potency |
TKC111738
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
16 |
nM |
Potency |
TKC112789
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
1000 |
nM |
Potency |
TKC112906
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
5012 |
nM |
Potency |
TKC114819
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
12589 |
nM |
Potency |
TKC117993
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
2000 |
nM |
EC50 |
TKC117997
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
40 |
nM |
EC50 |
TKC118004
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
2512 |
nM |
Potency |
TKC118012
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
600 |
nM |
EC50 |
TKC118131
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
126 |
nM |
Potency |
TKC134897
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
3400 |
nM |
IC50 |
TKC137120
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
200 |
nM |
IC50 |
TKC137126
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
2400 |
nM |
IC50 |
TKC137243
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
200 |
nM |
IC50 |
TKC144475
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
25000 |
nM |
IC50 |
TKC151571
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
7943 |
nM |
Potency |
TKC205806
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
5012 |
nM |
Potency |
TKC206042
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
6310 |
nM |
Potency |
TKC206395
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
12589 |
nM |
Potency |
TKC206453
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
25119 |
nM |
Potency |
TKC206617
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
12700 |
nM |
IC50 |
TKC206688
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
63 |
nM |
Potency |
TKC206726
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
79 |
nM |
Potency |
TKC206760
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
50119 |
nM |
Potency |
TKC206780
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
3981 |
nM |
Potency |
TKC206812
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
79433 |
nM |
Potency |
TKC206816
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
12589 |
nM |
Potency |
TKC206872
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
1000 |
nM |
Potency |
TKC206889
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
501 |
nM |
Potency |
TKC206890
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
20 |
nM |
EC50 |
TKC206901
|
Q16665 |
Hypoxia-inducible factor 1-alpha |
None |
159 |
nM |
Potency |
TKC026309
|
Q99814 |
Endothelial PAS domain-containing protein 1 |
None |
3300 |
nM |
EC50 |
TKC035150
|
Q99814 |
Endothelial PAS domain-containing protein 1 |
None |
10800 |
nM |
IC50 |
TKC045708
|
Q99814 |
Endothelial PAS domain-containing protein 1 |
None |
4200 |
nM |
EC50 |
TKC045868
|
Q99814 |
Endothelial PAS domain-containing protein 1 |
None |
1200 |
nM |
EC50 |
TKC046523
|
Q99814 |
Endothelial PAS domain-containing protein 1 |
None |
>100000 |
nM |
EC50 |
TKC100652
|
Q99814 |
Endothelial PAS domain-containing protein 1 |
None |
3400 |
nM |
EC50 |
TKC101122
|
Q99814 |
Endothelial PAS domain-containing protein 1 |
None |
6200 |
nM |
EC50 |
TKC103124
|
Q99814 |
Endothelial PAS domain-containing protein 1 |
None |
148900 |
nM |
EC50 |
TKC104992
|
Q99814 |
Endothelial PAS domain-containing protein 1 |
None |
107500 |
nM |
EC50 |
TKC105151
|
Q99814 |
Endothelial PAS domain-containing protein 1 |
None |
183300 |
nM |
EC50 |
TKC118419
|
Q99814 |
Endothelial PAS domain-containing protein 1 |
None |
3930 |
nM |
IC50 |
TKC143885
|
Q99814 |
Endothelial PAS domain-containing protein 1 |
None |
14400 |
nM |
IC50 |
TKC165028
|
Q99814 |
Endothelial PAS domain-containing protein 1 |
None |
11800 |
nM |
EC50 |
TKC115268
|
Q99835 |
Smoothened homolog |
None |
36 |
% |
Activity |
TKC115284
|
Q99835 |
Smoothened homolog |
None |
28 |
% |
Activity |
TKC206385
|
Q99835 |
Smoothened homolog |
None |
70 |
% |
Activity |
TKC066096
|
Q9NR96 |
Toll-like receptor 9 |
None |
3015 |
nM |
IC50 |
TKC076529
|
Q9NR96 |
Toll-like receptor 9 |
None |
>49739 |
nM |
IC50 |
TKC076529
|
Q9NR96 |
Toll-like receptor 9 |
None |
>49739 |
nM |
IC50 |
TKC082378
|
Q9NR96 |
Toll-like receptor 9 |
None |
7929 |
nM |
IC50 |
TKC082378
|
Q9NR96 |
Toll-like receptor 9 |
None |
7929 |
nM |
IC50 |