Basic Information

Terpenoid ID TKC025058
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 38

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC025058 P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform PIK3CA 100 nM IC50
TKC025058 P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 1000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P42336 PK3CA_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P42336 PK3CA_HUMAN Follicular lymphoma [ICD-11: 2A80]
P42336 PK3CA_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P42336 PK3CA_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P42336 PK3CA_HUMAN Prostate cancer [ICD-11: 2C82]
P42336 PK3CA_HUMAN Colorectal cancer [ICD-11: 2B91]
P42336 PK3CA_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P48736 PK3CG_HUMAN Follicular lymphoma [ICD-11: 2A80]
P48736 PK3CG_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P48736 PK3CG_HUMAN Mature B-cell leukaemia [ICD-11: 2A82]
P48736 PK3CG_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P48736 PK3CG_HUMAN Brain cancer [ICD-11: 2A00]
P48736 PK3CG_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P48736 PK3CG_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P48736 PK3CG_HUMAN Diffuse large B-cell lymphoma [ICD-11: 2A81]
P48736 PK3CG_HUMAN Myelodysplastic syndrome [ICD-11: 2A37]
P48736 PK3CG_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P48736 PK3CG_HUMAN Adrenal cancer [ICD-11: 2D11]
P48736 PK3CG_HUMAN Bladder cancer [ICD-11: 2C94]
P48736 PK3CG_HUMAN Endometrial cancer [ICD-11: 2C76]
P48736 PK3CG_HUMAN Head and neck cancer [ICD-11: 2D42]
P48736 PK3CG_HUMAN Liver cancer [ICD-11: 2C12]
P48736 PK3CG_HUMAN Melanoma [ICD-11: 2C30]
P48736 PK3CG_HUMAN Metastatic lymph node neoplasm [ICD-11: 2D60]
P48736 PK3CG_HUMAN Pain [ICD-11: MG30-MG3Z]
P48736 PK3CG_HUMAN Peritoneal cancer [ICD-11: 2C51]
P48736 PK3CG_HUMAN BCR-ABL1-negative chronic myeloid leukaemia [ICD-11: 2A41]
P48736 PK3CG_HUMAN Colorectal cancer [ICD-11: 2B91]
P48736 PK3CG_HUMAN Innate/adaptive immunodeficiency [ICD-11: 4A00]
P48736 PK3CG_HUMAN Myocardial infarction [ICD-11: BA41-BA43]
P48736 PK3CG_HUMAN B-cell lymphoma [ICD-11: 2A86]
P48736 PK3CG_HUMAN Lymphoma [ICD-11: 2A80-2A86]
P48736 PK3CG_HUMAN Pleural mesothelioma [ICD-11: 2C26]
P48736 PK3CG_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P48736 PK3CG_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P48736 PK3CG_HUMAN Bacterial infection [ICD-11: 1A00-1C4Z]
P48736 PK3CG_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P48736 PK3CG_HUMAN Prostate cancer [ICD-11: 2C82]