Basic Information

Terpenoid ID TKC026870
Chirality TKC041411
Cell line 0
Protein target 9
DiseaseNCIT 0
ORDO 0
ICD 20

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC026870 P10636 Microtubule-associated protein tau MAPT 5012 nM Potency
TKC026870 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 84 % Inhibition
TKC026870 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 85 % Inhibition
TKC026870 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 3162 nM Potency
TKC026870 Q9UBT6 DNA polymerase kappa POLK 11220 nM Potency
TKC026870 O94782 Ubiquitin carboxyl-terminal hydrolase 1 USP1 10000 nM Potency
TKC026870 P11712 Cytochrome P450 2C9 CYP2C9 19953 nM Potency
TKC026870 P33261 Cytochrome P450 2C19 CYP2C19 15849 nM Potency
TKC026870 P10828 Thyroid hormone receptor beta THRB 2239 nM Potency
TKC026870 P02545 Prelamin-A/C LMNA 2818 nM Potency
TKC026870 O75604 Ubiquitin carboxyl-terminal hydrolase 2 USP2 7943 nM Potency
TKC026870 P49768 Presenilin-1 PSEN1 >100000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]
O94782 UBP1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11712 CP2C9_HUMAN Bacterial infection [ICD-11: 1A00-1C4Z]
P10828 THB_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P10828 THB_HUMAN Hypo-thyroidism [ICD-11: 5A00]
P10828 THB_HUMAN Inborn lipid metabolism error [ICD-11: 5C52]
P10828 THB_HUMAN Skin postprocedural disorder [ICD-11: EL8Y]
P10828 THB_HUMAN Thyrotoxicosis [ICD-11: 5A02]
O75604 UBP2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P49768 PSN1_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
P49768 PSN1_HUMAN Shoulder lesion [ICD-11: FB53]
P49768 PSN1_HUMAN Soft tissue disorder [ICD-11: FB56]