Basic Information

Terpenoid ID TKC130327
Chirality TKC020987
Cell line 0
Protein target 3
DiseaseNCIT 0
ORDO 0
ICD 5

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC130327 MHCC97H MH60.BSF-2; MH60-BSF-2; MH60 100000.0 nM IC50
TKC130327 SMMC-7721 SMMC 7721; SMMC7721; H7721; H-7721 100000.0 nM IC50 C27677
TKC130327 HepG2 100000.0 nM IC50 C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC130327 P00352 Retinal dehydrogenase 1 ALDH1A1 28184 nM Potency
TKC130327 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 251 nM Potency
TKC130327 P02791 Ferritin light chain FTL 31623 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]