Basic Information

Terpenoid ID TKC152398
Cell line 0
Protein target 3
DiseaseNCIT 0
ORDO 0
ICD 12

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC152398 THP-1 THP1; THP 1; THPI; THP-1(ATCC); THP-1-O; O-THP-1; Tohoku Hospital Pediatrics-1 3300.0 nM IC50 C9163 Orphanet_514
TKC152398 HepG2 40340.0 nM IC50 C3728 Orphanet_449
TKC152398 MCF7 49230.0 nM IC50 C4194
TKC152398 A549 38150.0 nM IC50 C3512
TKC152398 PC-12 PC 12; PC12 3.0 % Activity C5650
TKC152398 SH-SY5Y SH-Sy5y; SHSY5Y; SHSY-5Y; SK-SH-SY5Y; SY5Y; SH-SY5Y Parental 68.0 % Activity C3270 Orphanet_635

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC152398 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 80 nM Ki
TKC152398 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 130 nM Ki
TKC152398 O42275 Acetylcholinesterase ache -3 % Inhibition
TKC152398 P0DTD1 Replicase polyprotein 1ab rep 12 % Inhibition
TKC152398 P81908 Cholinesterase BCHE -3 % Inhibition
TKC152398 P05067 Amyloid-beta precursor protein APP 100000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P05067 A4_HUMAN Diagnostic imaging [ICD-11: N.A.]
P05067 A4_HUMAN Alzheimer disease [ICD-11: 8A20]
P05067 A4_HUMAN Desmoid tumour [ICD-11: 2F7C]
P05067 A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P05067 A4_HUMAN Retinopathy [ICD-11: 9B71]
P05067 A4_HUMAN Dystrophic epidermolysis bullosa [ICD-11: EC32]
P05067 A4_HUMAN Amyloidosis [ICD-11: 5D00]
P05067 A4_HUMAN Macular degeneration [ICD-11: 9B75]
P05067 A4_HUMAN Intracranial injury [ICD-11: NA07]
P05067 A4_HUMAN Brain cancer [ICD-11: 2A00]
P05067 A4_HUMAN Dissociative neurological symptom disorder [ICD-11: 6B60]
P05067 A4_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]