Basic Information

Terpenoid ID TKC039332
Cell line 0
Protein target 22
DiseaseNCIT 0
ORDO 0
ICD 35

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC039332 HepG2 25119.0 nM Potency C3728 Orphanet_449
TKC039332 BJ 3090.0 nM EC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC039332 P10636 Microtubule-associated protein tau MAPT 15849 nM Potency
TKC039332 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 4611 nM Potency
TKC039332 P84022 Mothers against decapentaplegic homolog 3 SMAD3 12589 nM Potency
TKC039332 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 8913 nM Potency
TKC039332 Q99700 Ataxin-2 ATXN2 22387 nM Potency
TKC039332 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 5012 nM Potency
TKC039332 Q962Y6 Thioredoxin glutathione reductase TGR 35481 nM Potency
TKC039332 Q9UNA4 DNA polymerase iota POLI 28184 nM Potency
TKC039332 O75496 Geminin GMNN 2060 nM Potency
TKC039332 Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G APOBEC3G 35481 nM Potency
TKC039332 O94782 Ubiquitin carboxyl-terminal hydrolase 1 USP1 22387 nM Potency
TKC039332 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 PIN1 50119 nM Potency
TKC039332 P83916 Chromobox protein homolog 1 CBX1 100000 nM Potency
TKC039332 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 23100 nM Potency
TKC039332 P46063 ATP-dependent DNA helicase Q1 RECQL 631 nM Potency
TKC039332 P49798 Regulator of G-protein signaling 4 RGS4 79433 nM Potency
TKC039332 Q9Y253 DNA polymerase eta POLH 31623 nM Potency
TKC039332 Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F APOBEC3F 5012 nM Potency
TKC039332 P51450 Nuclear receptor ROR-gamma Rorc 7080 nM Potency
TKC039332 P51151 Ras-related protein Rab-9A RAB9A 3162 nM Potency
TKC039332 Q194T2 Non-structural protein 1 NS1 3162 nM Potency
TKC039332 P14618 Pyruvate kinase PKM PKM 25119 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]
O94782 UBP1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q13526 PIN1_HUMAN Lung cancer [ICD-11: 2C25]
Q13526 PIN1_HUMAN Nasopharyngeal cancer [ICD-11: 2B6B]
P51151 RAB9A_HUMAN Fungal infection [ICD-11: 1F29-1F2F]
P14618 KPYM_HUMAN Pain [ICD-11: MG30-MG3Z]
P14618 KPYM_HUMAN Renal cell carcinoma [ICD-11: 2C90]
P14618 KPYM_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]