Basic Information

Terpenoid ID TKC066631
Chirality TKC104159
Cell line 0
Protein target 14
DiseaseNCIT 0
ORDO 0
ICD 9

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC066631 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 14000.0 nM TGI C4349
TKC066631 HCC 2998 HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 12900.0 nM TGI C4349
TKC066631 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 13800.0 nM TGI C4910
TKC066631 HCT-15 HCT-15; HCT.15; HCT15 13900.0 nM TGI C4349
TKC066631 HT-29 HT 29; HT29 14300.0 nM TGI C4349
TKC066631 KM12 KM-12; KM.12 14200.0 nM TGI C4910
TKC066631 SW-620 SW-620; SW 620; SW.620 14400.0 nM TGI C4349
TKC066631 Leukemia cells 18500.0 nM TGI
TKC066631 NSCLC NSCLCN6 13100.0 nM TGI C3493
TKC066631 HEK293 14581.0 nM Potency

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC066631 Q16637 Survival motor neuron protein SMN1,SMN2 35481 nM Potency
TKC066631 Q16637 Survival motor neuron protein SMN1,SMN2 35481 nM Potency
TKC066631 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 2239 nM Potency
TKC066631 O75496 Geminin GMNN 7308 nM Potency
TKC066631 P00811 Beta-lactamase ampC 25119 nM Potency
TKC066631 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 16360 nM Potency
TKC066631 Q6W5P4 Neuropeptide S receptor NPSR1 12589 nM Potency
TKC066631 P25779 Cruzipain 3162 nM Potency
TKC066631 Q9F4F7 4'-phosphopantetheinyl transferase ffp ffp 4467 nM Potency
TKC066631 Q9NR56 Muscleblind-like protein 1 MBNL1 100 nM Potency
TKC066631 P51450 Nuclear receptor ROR-gamma Rorc 891 nM Potency
TKC066631 P02545 Prelamin-A/C LMNA 17783 nM Potency
TKC066631 P42858 Huntingtin HTT 35481 nM Potency
TKC066631 P17861 X-box-binding protein 1 XBP1 9470 nM IC50
TKC066631 P35639 DNA damage-inducible transcript 3 protein Ddit3 >5960 nM IC50
TKC066631 P35639 DNA damage-inducible transcript 3 protein Ddit3 >10000 nM IC50
TKC066631 O43521 Bcl-2-like protein 11 BCL2L11 65530 nM EC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]
P25779 CYSP_TRYCR Parasitic worm infestation [ICD-11: 1F90]
P25779 CYSP_TRYCR Malaria [ICD-11: 1F40-1F45]
P42858 HD_HUMAN Choreiform disorder [ICD-11: 8A01]