Basic Information

Terpenoid ID TKC112785
Cell line 0
Protein target 3
DiseaseNCIT 0
ORDO 0
ICD 5

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC112785 P11473 Vitamin D3 receptor VDR >40100 nM IC50
TKC112785 P20309 Muscarinic acetylcholine receptor M3 CHRM3 >10000 nM Ki
TKC112785 P08173 Muscarinic acetylcholine receptor M4 CHRM4 >10000 nM Ki
TKC112785 P08912 Muscarinic acetylcholine receptor M5 CHRM5 >10000 nM Ki
TKC112785 P08482 Muscarinic acetylcholine receptor M1 Chrm1 >10000 nM Ki
TKC112785 O15439 ATP-binding cassette sub-family C member 4 ABCC4 9 % Activity
TKC112785 Q8TDU6 G-protein coupled bile acid receptor 1 GPBAR1 540 nM EC50
TKC112785 Q14973 Sodium/bile acid cotransporter SLC10A1 24 % Activity
TKC112785 P29317 Ephrin type-A receptor 2 EPHA2 48978 nM IC50
TKC112785 Q96J66 ATP-binding cassette sub-family C member 11 ABCC11 16 % Activity
TKC112785 Q11205 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 St3gal2 25000 nM IC50
TKC112785 P08483 Muscarinic acetylcholine receptor M3 Chrm3 >10000 nM Ki

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P11473 VDR_HUMAN Chronic kidney disease [ICD-11: GB61]
P11473 VDR_HUMAN Hair/hair growth developmental defect [ICD-11: LC30]
P11473 VDR_HUMAN Hyper-parathyroidism [ICD-11: 5A51]
P11473 VDR_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P11473 VDR_HUMAN Mineral deficiency [ICD-11: 5B5K]
P11473 VDR_HUMAN Psoriasis [ICD-11: EA90]
P11473 VDR_HUMAN Vitamin deficiency [ICD-11: 5B55-5B5F]
P11473 VDR_HUMAN Low bone mass disorder [ICD-11: FB83]
P11473 VDR_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11473 VDR_HUMAN Prostate cancer [ICD-11: 2C82]
P11473 VDR_HUMAN Prostate disease [ICD-11: GA91]
P11473 VDR_HUMAN Abnormal micturition [ICD-11: MF50]
P11473 VDR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11473 VDR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P11473 VDR_HUMAN Acne vulgaris [ICD-11: ED80]
P20309 ACM3_HUMAN Asthma [ICD-11: CA23]
P20309 ACM3_HUMAN Chronic obstructive pulmonary disease [ICD-11: CA22]
P20309 ACM3_HUMAN Functional bladder disorder [ICD-11: GC50]
P20309 ACM3_HUMAN Glaucoma [ICD-11: 9C61]
P20309 ACM3_HUMAN Nausea/vomiting [ICD-11: MD90]
P20309 ACM3_HUMAN Peptic ulcer [ICD-11: DA61]
P20309 ACM3_HUMAN Respiratory system disease [ICD-11: CB40-CB7Z]
P20309 ACM3_HUMAN Sebaceous gland disorder [ICD-11: ED91]
P20309 ACM3_HUMAN Sjogren syndrome [ICD-11: 4A43]
P20309 ACM3_HUMAN Tonus and reflex abnormality [ICD-11: MB47]
P20309 ACM3_HUMAN Abnormal micturition [ICD-11: MF50]
P20309 ACM3_HUMAN Alzheimer disease [ICD-11: 8A20]
P08173 ACM4_HUMAN Asthma [ICD-11: CA23]
P08173 ACM4_HUMAN Eye anterior segment structural developmental anomaly [ICD-11: LA11]
P08173 ACM4_HUMAN Glaucoma [ICD-11: 9C61]
P08173 ACM4_HUMAN Nausea/vomiting [ICD-11: MD90]
P08173 ACM4_HUMAN Respiratory system disease [ICD-11: CB40-CB7Z]
P08173 ACM4_HUMAN Attention deficit hyperactivity disorder [ICD-11: 6A05]
P08912 ACM5_HUMAN Abnormal micturition [ICD-11: MF50]
P08912 ACM5_HUMAN Anterior uveitis [ICD-11: 9A96]
P08912 ACM5_HUMAN Appearance/behaviour symptom [ICD-11: MB23]
P08912 ACM5_HUMAN Asthma [ICD-11: CA23]
P08912 ACM5_HUMAN Brain disease [ICD-11: 8C70-8E61]
P08912 ACM5_HUMAN Central and peripheral nervous disease [ICD-11: 8A04-8E7Z]
P08912 ACM5_HUMAN Chronic obstructive pulmonary disease [ICD-11: CA22]
P08912 ACM5_HUMAN Cognition symptoms/signs/clinical sympton [ICD-11: MB21]
P08912 ACM5_HUMAN Cough [ICD-11: MD12]
P08912 ACM5_HUMAN Digestive system disease [ICD-11: DE2Z]
P08912 ACM5_HUMAN Female pelvic pain [ICD-11: GA34]
P08912 ACM5_HUMAN Functional bladder disorder [ICD-11: GC50]
P08912 ACM5_HUMAN Gastritis [ICD-11: DA42]
P08912 ACM5_HUMAN General examination [ICD-11: QA00]
P08912 ACM5_HUMAN Glaucoma [ICD-11: 9C61]
P08912 ACM5_HUMAN Hypertension [ICD-11: BA00-BA04]
P08912 ACM5_HUMAN Infectious gastroenteritis/colitis [ICD-11: 1A40]
P08912 ACM5_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P08912 ACM5_HUMAN Nystagmus [ICD-11: 9C84]
P08912 ACM5_HUMAN Oesophagus motility disorder [ICD-11: DA21]
P08912 ACM5_HUMAN Pain [ICD-11: MG30-MG3Z]
P08912 ACM5_HUMAN Pancreatitis [ICD-11: DC31-DC34]
P08912 ACM5_HUMAN Parkinsonism [ICD-11: 8A00]
P08912 ACM5_HUMAN Peptic ulcer [ICD-11: DA61]
P08912 ACM5_HUMAN Polyuria [ICD-11: MF55]
P08912 ACM5_HUMAN Tonus and reflex abnormality [ICD-11: MB47]
P08912 ACM5_HUMAN Unspecific substance harmful effect [ICD-11: NE6Z]
P08912 ACM5_HUMAN Urgency [ICD-11: N.A.]
P08912 ACM5_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08912 ACM5_HUMAN Depression [ICD-11: 6A70-6A7Z]
P08912 ACM5_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P08912 ACM5_HUMAN Schizophrenia [ICD-11: 6A20]
P08912 ACM5_HUMAN Alzheimer disease [ICD-11: 8A20]
P08912 ACM5_HUMAN Gastric ulcer [ICD-11: DA60]
P08912 ACM5_HUMAN Attention deficit hyperactivity disorder [ICD-11: 6A05]
P08912 ACM5_HUMAN Dissociative neurological symptom disorder [ICD-11: 6B60]
P08912 ACM5_HUMAN Myasthenia gravis [ICD-11: 8C6Y]
P08912 ACM5_HUMAN Vasomotor/allergic rhinitis [ICD-11: CA08]
Q8TDU6 GPBAR_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
Q8TDU6 GPBAR_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
Q8TDU6 GPBAR_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
Q14973 NTCP_HUMAN Hepatitis virus infection [ICD-11: 1E50-1E51]
Q14973 NTCP_HUMAN Autoimmune liver disease [ICD-11: DB96]
Q14973 NTCP_HUMAN Gallbladder/bile ducts/liver structural developmental anomaly [ICD-11: LB20]
Q14973 NTCP_HUMAN Inborn porphyrin/heme metabolism error [ICD-11: 5C58]
P29317 EPHA2_HUMAN Brain cancer [ICD-11: 2A00]
P29317 EPHA2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]