Basic Information

Terpenoid ID TKC112906
Chirality TKC206764
Cell line 0
Protein target 12
DiseaseNCIT 0
ORDO 0
ICD 26

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC112906 P00352 Retinal dehydrogenase 1 ALDH1A1 501 nM Potency
TKC112906 P11473 Vitamin D3 receptor VDR 25119 nM Potency
TKC112906 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 25929 nM Potency
TKC112906 P08684 Cytochrome P450 3A4 CYP3A4 10000 nM Potency
TKC112906 Q99700 Ataxin-2 ATXN2 2818 nM Potency
TKC112906 P05177 Cytochrome P450 1A2 CYP1A2 10000 nM AC50
TKC112906 P0DTD1 Replicase polyprotein 1ab rep 3 % Inhibition
TKC112906 P33261 Cytochrome P450 2C19 CYP2C19 7943 nM AC50
TKC112906 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 EHMT2 8913 nM Potency
TKC112906 Q16665 Hypoxia-inducible factor 1-alpha HIF1A 5012 nM Potency
TKC112906 P16050 Polyunsaturated fatty acid lipoxygenase ALOX15 ALOX15 6310 nM Potency
TKC112906 P51450 Nuclear receptor ROR-gamma Rorc 14125 nM Potency
TKC112906 P02545 Prelamin-A/C LMNA 14125 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P11473 VDR_HUMAN Chronic kidney disease [ICD-11: GB61]
P11473 VDR_HUMAN Hair/hair growth developmental defect [ICD-11: LC30]
P11473 VDR_HUMAN Hyper-parathyroidism [ICD-11: 5A51]
P11473 VDR_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P11473 VDR_HUMAN Mineral deficiency [ICD-11: 5B5K]
P11473 VDR_HUMAN Psoriasis [ICD-11: EA90]
P11473 VDR_HUMAN Vitamin deficiency [ICD-11: 5B55-5B5F]
P11473 VDR_HUMAN Low bone mass disorder [ICD-11: FB83]
P11473 VDR_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11473 VDR_HUMAN Prostate cancer [ICD-11: 2C82]
P11473 VDR_HUMAN Prostate disease [ICD-11: GA91]
P11473 VDR_HUMAN Abnormal micturition [ICD-11: MF50]
P11473 VDR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11473 VDR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P11473 VDR_HUMAN Acne vulgaris [ICD-11: ED80]
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
Q96KQ7 EHMT2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96KQ7 EHMT2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q96KQ7 EHMT2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q16665 HIF1A_HUMAN Adrenomedullary hyperfunction [ICD-11: 5A75]
Q16665 HIF1A_HUMAN Brain cancer [ICD-11: 2A00]
Q16665 HIF1A_HUMAN Lymphoma [ICD-11: 2A80-2A86]
Q16665 HIF1A_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q16665 HIF1A_HUMAN Pulmonary hypertension [ICD-11: BB01]