Basic Information

Terpenoid ID TKC045868
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 5

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC045868 MCF7 290.0 nM IC50 C4194
TKC045868 HT-29 HT 29; HT29 390.0 nM IC50 C4349
TKC045868 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 450.0 nM IC50 C27677
TKC045868 KB KB (HeLa derivative); HeLa-KB; Strain KB 370.0 nM IC50 C27677
TKC045868 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 3400.0 nM IC50 C7978
TKC045868 SK-MEL SK-Mel-1; SK Mel 1; SK-Mel 1; SK-Mel1; SKMEL-1; SkMEL-1; SKMEL1; SK 1 15300.0 nM IC50 C3224
TKC045868 BT-549 BT 549; BT.549; BT549 11200.0 nM IC50 C4194
TKC045868 Vero VERO; VeroCCL81; Vero 81; Vero-81; Verda reno 8200.0 nM IC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC045868 Q00653 Nuclear factor NF-kappa-B p100 subunit NFKB2 5000 nM IC50
TKC045868 Q99814 Endothelial PAS domain-containing protein 1 EPAS1 1200 nM EC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q00653 NFKB2_HUMAN Ulcerative colitis [ICD-11: DD71]
Q99814 EPAS1_HUMAN Adrenomedullary hyperfunction [ICD-11: 5A75]
Q99814 EPAS1_HUMAN Renal cell carcinoma [ICD-11: 2C90]
Q99814 EPAS1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q99814 EPAS1_HUMAN Brain cancer [ICD-11: 2A00]
Q99814 EPAS1_HUMAN Adrenomedullary hyperfunction [ICD-11: 5A75]
Q99814 EPAS1_HUMAN Brain cancer [ICD-11: 2A00]
Q99814 EPAS1_HUMAN Renal cell carcinoma [ICD-11: 2C90]