Basic Information

Terpenoid ID TKC169452
Cell line 0
Protein target 8
DiseaseNCIT 0
ORDO 0
ICD 13

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC169452 P18031 Tyrosine-protein phosphatase non-receptor type 1 PTPN1 0 nM IC50
TKC169452 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 2239 nM Potency
TKC169452 P51450 Nuclear receptor ROR-gamma Rorc 0 nM Potency
TKC169452 P42858 Huntingtin HTT 1000 nM Potency
TKC169452 P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit PPP1CC 0 nM IC50
TKC169452 Q8AWE3 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B 0 nM IC50
TKC169452 P97697 Inositol monophosphatase 1 Impa1 40 nM Potency
TKC169452 Q15172 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform PPP2R5A 0 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P18031 PTN1_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P18031 PTN1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P18031 PTN1_HUMAN Obesity [ICD-11: 5B80-5B81]
P18031 PTN1_HUMAN Ophthalmic devices/implants/grafts injury [ICD-11: PK97]
P18031 PTN1_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P18031 PTN1_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]
P42858 HD_HUMAN Choreiform disorder [ICD-11: 8A01]