Basic Information

Terpenoid ID TKC206042
Cell line 0
Protein target 14
DiseaseNCIT 0
ORDO 0
ICD 12

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC206042 MDCK MDCK (NBL-2); NBL-2; Madin-Darby Canine Kidney; Madin Darby Canine Kidney 2280.0 ug ml-1 TC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC206042 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 5 nM Potency
TKC206042 Q9UBT6 DNA polymerase kappa POLK 670 nM Potency
TKC206042 O94782 Ubiquitin carboxyl-terminal hydrolase 1 USP1 28184 nM Potency
TKC206042 P05177 Cytochrome P450 1A2 CYP1A2 12589 nM AC50
TKC206042 P10635 Cytochrome P450 2D6 CYP2D6 7943 nM AC50
TKC206042 B2RXH2 Lysine-specific demethylase 4E KDM4E 11220 nM Potency
TKC206042 O00255 Menin MEN1 14125 nM Potency
TKC206042 O97447 Putative fructose-1,6-bisphosphate aldolase fba 5610 nM Potency
TKC206042 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 12589 nM Potency
TKC206042 Q16665 Hypoxia-inducible factor 1-alpha HIF1A 6310 nM Potency
TKC206042 P16050 Polyunsaturated fatty acid lipoxygenase ALOX15 ALOX15 3981 nM Potency
TKC206042 O94925 Glutaminase kidney isoform, mitochondrial GLS 7943 nM Potency
TKC206042 O75604 Ubiquitin carboxyl-terminal hydrolase 2 USP2 5012 nM Potency
TKC206042 P16473 Thyrotropin receptor TSHR 15849 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O94782 UBP1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P10635 CP2D6_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
P10635 CP2D6_HUMAN Malaria [ICD-11: 1F40-1F45]
P10635 CP2D6_HUMAN Migraine [ICD-11: 8A80]
Q16665 HIF1A_HUMAN Adrenomedullary hyperfunction [ICD-11: 5A75]
Q16665 HIF1A_HUMAN Brain cancer [ICD-11: 2A00]
Q16665 HIF1A_HUMAN Lymphoma [ICD-11: 2A80-2A86]
Q16665 HIF1A_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q16665 HIF1A_HUMAN Pulmonary hypertension [ICD-11: BB01]
O75604 UBP2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P16473 TSHR_HUMAN Hypo-thyroidism [ICD-11: 5A00]
P16473 TSHR_HUMAN Thyroid cancer [ICD-11: 2D10]