Basic Information

Terpenoid ID TKC206395
Chirality TKC014820
Cell line 0
Protein target 7
DiseaseNCIT 0
ORDO 0
ICD 12

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC206395 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 21 nM Potency
TKC206395 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 37 nM Potency
TKC206395 O95398 Rap guanine nucleotide exchange factor 3 RAPGEF3 125893 nM Potency
TKC206395 P84022 Mothers against decapentaplegic homolog 3 SMAD3 35481 nM Potency
TKC206395 Q99700 Ataxin-2 ATXN2 5012 nM Potency
TKC206395 O75496 Geminin GMNN 65 nM Potency
TKC206395 Q16665 Hypoxia-inducible factor 1-alpha HIF1A 12589 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O95398 RPGF3_HUMAN Epidermal dysplasias [ICD-11: EK90]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q16665 HIF1A_HUMAN Adrenomedullary hyperfunction [ICD-11: 5A75]
Q16665 HIF1A_HUMAN Brain cancer [ICD-11: 2A00]
Q16665 HIF1A_HUMAN Lymphoma [ICD-11: 2A80-2A86]
Q16665 HIF1A_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q16665 HIF1A_HUMAN Pulmonary hypertension [ICD-11: BB01]