Basic Information

Terpenoid ID TKC033871
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 24

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC033871 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 8900.0 nM IC50 C4863
TKC033871 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 9600.0 nM IC50 C4910
TKC033871 A549 4900.0 nM IC50 C3512

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC033871 P08581 Hepatocyte growth factor receptor MET 50000 nM IC50
TKC033871 F1MN93 DNA topoisomerase I TOP1 >90 % Inhibition
TKC033871 Q75ZY9 Hepatocyte growth factor receptor MET 50 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P08581 MET_HUMAN Brain cancer [ICD-11: 2A00]
P08581 MET_HUMAN Liver cancer [ICD-11: 2C12]
P08581 MET_HUMAN Lung cancer [ICD-11: 2C25]
P08581 MET_HUMAN Non-small cell lung cancer [ICD-11: 2C25]
P08581 MET_HUMAN Ovarian cancer [ICD-11: 2C73]
P08581 MET_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08581 MET_HUMAN Thyroid cancer [ICD-11: 2D10]
P08581 MET_HUMAN Chronic arterial occlusive disease [ICD-11: BD4Z]
P08581 MET_HUMAN Heart disease [ICD-11: BA41-BA42]
P08581 MET_HUMAN Renal cell carcinoma [ICD-11: 2C90]
P08581 MET_HUMAN Stomach cancer [ICD-11: 2B72]
P08581 MET_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P08581 MET_HUMAN Biliary tract cancer [ICD-11: 2C17]
P08581 MET_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P08581 MET_HUMAN Injury [ICD-11: NA00-ND5Z]
P08581 MET_HUMAN Metastatic lymph node neoplasm [ICD-11: 2D60]
P08581 MET_HUMAN Sarcoma [ICD-11: 2A60-2C35]
P08581 MET_HUMAN Alzheimer disease [ICD-11: 8A20]
P08581 MET_HUMAN Colorectal cancer [ICD-11: 2B91]
P08581 MET_HUMAN Fibrosis [ICD-11: GA14-GC01]
P08581 MET_HUMAN Glaucoma [ICD-11: 9C61]
P08581 MET_HUMAN Head and neck cancer [ICD-11: 2D42]
P08581 MET_HUMAN Liver disease [ICD-11: DB90-DB9Z]
P08581 MET_HUMAN Melanoma [ICD-11: 2C30]
P08581 MET_HUMAN Nasopharyngitis [ICD-11: CA00]