Basic Information

Terpenoid ID TKC100990
Chirality TKC039868
Cell line 0
Protein target 4
DiseaseNCIT 0
ORDO 0
ICD 10

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC100990 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 562 nM Potency
TKC100990 P05177 Cytochrome P450 1A2 CYP1A2 63 nM AC50
TKC100990 Q16665 Hypoxia-inducible factor 1-alpha HIF1A 159 nM Potency
TKC100990 P02545 Prelamin-A/C LMNA 355 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]
Q16665 HIF1A_HUMAN Adrenomedullary hyperfunction [ICD-11: 5A75]
Q16665 HIF1A_HUMAN Brain cancer [ICD-11: 2A00]
Q16665 HIF1A_HUMAN Lymphoma [ICD-11: 2A80-2A86]
Q16665 HIF1A_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q16665 HIF1A_HUMAN Pulmonary hypertension [ICD-11: BB01]