Basic Information
| Terpenoid ID | TKC134702 |
|
| Chirality | TKC038268 | |
| Cell line | 0 | |
| Protein target | 43 | |
| DiseaseNCIT | 0 | |
| ORDO | 0 | |
| ICD | 111 |
| Terpenoid ID | TKC134702 |
|
| Chirality | TKC038268 | |
| Cell line | 0 | |
| Protein target | 43 | |
| DiseaseNCIT | 0 | |
| ORDO | 0 | |
| ICD | 111 |
| ID | Cell Line | Synonyms | Value | Unit | Type | NCIt | ORDO |
|---|---|---|---|---|---|---|---|
| TKC134702 | SK-MEL-5 | SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel | 1303.0 | nM | GI50 | C3510 | |
| TKC134702 | Tumor cancer cell line | 1.0 | uM | MG MID | |||
| TKC134702 | Colon carcinoma cells | 1.0 | uM | MG MID | C120044 | ||
| TKC134702 | A-431 | A431; A431/P | 800.0 | nM | IC50 | C4819 | |
| TKC134702 | HEp-2 | Hep-2; HEP-2; Hep2 (HeLa derivative); HEp-2/HeLa; Hep 2; Hep2; HEp2; HEP2; H.Ep.-2; H.Ep. #2; H.Ep. No. 2; Hep II; Human Epidermoid carcinoma #2; Human Epithelioma-2 | 800.0 | nM | IC50 | C27677 | |
| TKC134702 | MCF7 | 500.0 | nM | IC50 | C4194 | ||
| TKC134702 | OVCAR-3 | Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 | 1400.0 | nM | IC50 | C105555 | |
| TKC134702 | SW872 | SW-872; SW 872 | 1200.0 | nM | IC50 | C3194 | Orphanet_69078 |
| TKC134702 | ZR-75-1 | Zr-75-1; ZR751; ZR75-1; ZR75.1; ZR75_1 | 700.0 | nM | IC50 | C4194 | |
| TKC134702 | HL-60 | HL 60; HL.60 HL60; Human Leukemia-60 | 320.0 | nM | IC50 | C9154 | Orphanet_519 |
| TKC134702 | HepG2 | 11220.0 | nM | Potency | C3728 | Orphanet_449 | |
| TKC134702 | INS1 | INS1 | 2268.0 | nM | AC50 | C121566 | |
| TKC134702 | SN12C | SN-12C | 1355.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC134702 | MDA-N | MDAN | 2084.0 | nM | GI50 | C3802 | |
| TKC134702 | NCI-H23 | NCI.H23; NCI H23; H-23; H23; NCIH23 | 1660.0 | nM | GI50 | C3512 | |
| TKC134702 | ACHN | 1660.0 | nM | GI50 | C6975 | Orphanet_319298 | |
| TKC134702 | UO-31 | UO.31; UO31; U031 | 1679.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC134702 | SF-539 | SF-539; SF-539 BT; SF.539; SF 539 | 1986.0 | nM | GI50 | C3796 | Orphanet_251576 |
| TKC134702 | DU-145 | DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 | 3793.0 | nM | GI50 | C4863 | |
| TKC134702 | Malme-3M | MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer | 1687.0 | nM | GI50 | C3224 | |
| TKC134702 | A498 | A498 | 1858.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC134702 | K562 | K562; K.562; K 562; KO; GM05372; GM05372E | 280.0 | nM | IC50 | C9110 | Orphanet_521 |
| TKC134702 | MOLT-4 | Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D | 851.0 | nM | GI50 | C9142 | Orphanet_99861 |
| TKC134702 | HOP-62 | HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 | 5888.0 | nM | GI50 | C3512 | |
| TKC134702 | U-251 | U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) | 769.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC134702 | OVCAR-8 | OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 | 1483.0 | nM | GI50 | C105555 | |
| TKC134702 | OVCAR-5 | OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 | 1714.0 | nM | GI50 | C105555 | |
| TKC134702 | SNB-19 | SNB.19; SNB19; Surgical Neurology Branch-19 | 2582.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC134702 | MDA-MB-231 | MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 | 3954.0 | nM | GI50 | C5214 | |
| TKC134702 | DMS-273 | DMS-273; DMS273; Darmouth Medical School 273 | 1531.0 | nM | GI50 | C4917 | Orphanet_70573 |
| TKC134702 | TK-10 | TK.10; TK 10; TK10 | 4046.0 | nM | GI50 | C4033 | Orphanet_319276 |
| TKC134702 | SR | SR-786; SR786 | 594.0 | nM | GI50 | C37193 | Orphanet_300895 |
| TKC134702 | M19-MEL | M-19; M19 | 2818.0 | nM | GI50 | C3802 | |
| TKC134702 | SW-620 | SW-620; SW 620; SW.620 | 719.0 | nM | GI50 | C4349 | |
| TKC134702 | NCI-H522 | NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 | 242.0 | nM | GI50 | C3512 | |
| TKC134702 | KM12 | KM-12; KM.12 | 1535.0 | nM | GI50 | C4910 | |
| TKC134702 | M14 | M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 | 1977.0 | nM | GI50 | C3802 | |
| TKC134702 | NCI-H322M | NCI.H322M; H322M; H-322M; H-322m | 2333.0 | nM | GI50 | C2923 | |
| TKC134702 | RPMI-8226 | RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson | 532.0 | nM | GI50 | C3242 | Orphanet_29073 |
| TKC134702 | OVCAR-4 | OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 | 2767.0 | nM | GI50 | C105555 | |
| TKC134702 | LOX IMVI | LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX | 574.0 | nM | GI50 | C3802 | |
| TKC134702 | BT-549 | BT 549; BT.549; BT549 | 1040.0 | nM | GI50 | C4194 | |
| TKC134702 | SK-MEL-2 | SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 | 1862.0 | nM | GI50 | C3224 | |
| TKC134702 | A549 | 2904.0 | nM | GI50 | C3512 | ||
| TKC134702 | KM-20L2 | KM-20L2; KM 20L2; KM 2012 | 1730.0 | nM | GI50 | C4349 | |
| TKC134702 | HCC 2998 | HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 | 1514.0 | nM | GI50 | C4349 | |
| TKC134702 | SNB-75 | SNB.75; SNB75; Surgical Neurology Branch-75 | 35.0 | nM | GI50 | C3058 | Orphanet_360 |
| TKC134702 | HCT-116 | HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 | 511.0 | nM | GI50 | C4910 | |
| TKC134702 | HCT-15 | HCT-15; HCT.15; HCT15 | 290.0 | nM | IC50 | C4349 | |
| TKC134702 | SF-268 | SF-268; SF.268; SF 268 | 3499.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC134702 | EKVX | 3133.0 | nM | GI50 | C3512 | ||
| TKC134702 | LXFL 529 | LXFL-529L; LXFL529L; LXF 529 L; LXFL-529; LXFL 529; LXFL529; LXF 529 | 493.0 | nM | GI50 | C2926 | |
| TKC134702 | DMS-114 | DMS-114; DMS114; Darmouth Medical School 114 | 1452.0 | nM | GI50 | C4917 | Orphanet_70573 |
| TKC134702 | PC-3 | PC3; PC.3 | 1919.0 | nM | GI50 | C4863 | |
| TKC134702 | NCI-H460 | NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 | 1726.0 | nM | GI50 | C4450 | |
| TKC134702 | T47D | 2951.0 | nM | GI50 | C4194 | ||
| TKC134702 | UACC-62 | UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 | 1390.0 | nM | GI50 | C3224 | |
| TKC134702 | MDA-MB-435 | MDA-MB435; MDAMB435; MDA.MB.435; MDA-435; MDA 435; MDA435; MD Anderson-Metastatic Breast-435 | 1578.0 | nM | GI50 | C3802 | |
| TKC134702 | CAKI-1 | CAL 1; Centre Antoine Lacassagne-1 | 377.0 | nM | GI50 | C3224 | |
| TKC134702 | IGROV-1 | Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P | 2203.0 | nM | GI50 | C7979 | Orphanet_454723 |
| TKC134702 | SF-295 | SF-295; SF.295; SF 295 | 2773.0 | nM | GI50 | C3058 | Orphanet_360 |
| TKC134702 | 786-0 | 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT | 1253.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC134702 | UACC-257 | UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 | 1589.0 | nM | GI50 | C3224 | |
| TKC134702 | DLD-1 | DLD 1; DLD1; CoCL3 | 557.0 | nM | GI50 | C4349 | |
| TKC134702 | CCRF-CEM | CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C | 313.0 | nM | GI50 | C7953 | Orphanet_99861 |
| TKC134702 | NCI-H226 | NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 | 1629.0 | nM | GI50 | C45662 | Orphanet_50251 |
| TKC134702 | HT-29 | HT 29; HT29 | 1714.0 | nM | GI50 | C4349 | |
| TKC134702 | SK-MEL-28 | SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 | 1762.0 | nM | GI50 | C3510 | |
| TKC134702 | COLO 205 | Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 | 1560.0 | nM | GI50 | C4349 | |
| TKC134702 | RXF 393 | RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL | 466.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC134702 | HOP-18 | HOP 18; Hop 18; HOP18; Hop18; Hopkins-18 | 2018.0 | nM | GI50 | C4450 | |
| TKC134702 | SK-LU-1 | SK-Lu-1; SK LU 1; SK-Lu1; SK-LU1; SKLU-1; SKLU1; SKLU01 | 210.0 | nM | IC50 | C3512 | |
| TKC134702 | W256 | LLC-WRC256; Walker/LLC-WRC 256; Walker-256; Walker-Ca.256; Walker 256; W256; Lilly Laboratories Culture-Walker Rat Culture 256 | 316.0 | % | T/C | C64011 | |
| TKC134702 | Ehrlich | Ehrlich-Lettre; Ehrlich Lettre; E-La; EAT; EAT strain E; Ehrlich ascites; Ehrlich | 12.0 | % | Activity | C21678 | |
| TKC134702 | HeLa | HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri | 700.0 | nM | EC50 | C27677 |
| ID | Uniport | Pref_name | Gene name | value | unit | type |
|---|---|---|---|---|---|---|
| TKC134702 | P00352 | Retinal dehydrogenase 1 | ALDH1A1 | 25119 | nM | Potency |
| TKC134702 | P04062 | Lysosomal acid glucosylceramidase | GBA1 | 1585 | nM | Potency |
| TKC134702 | P10636 | Microtubule-associated protein tau | MAPT | 3548 | nM | Potency |
| TKC134702 | P11473 | Vitamin D3 receptor | VDR | 31623 | nM | Potency |
| TKC134702 | Q16637 | Survival motor neuron protein | SMN1,SMN2 | 6 | nM | Potency |
| TKC134702 | Q16637 | Survival motor neuron protein | SMN1,SMN2 | 6 | nM | Potency |
| TKC134702 | Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | TDP1 | 820 | nM | Potency |
| TKC134702 | Q00653 | Nuclear factor NF-kappa-B p100 subunit | NFKB2 | 10 | uM | IC100 |
| TKC134702 | O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | IDH1 | 1458 | nM | Potency |
| TKC134702 | P43220 | Glucagon-like peptide 1 receptor | GLP1R | 2512 | nM | Potency |
| TKC134702 | P84022 | Mothers against decapentaplegic homolog 3 | SMAD3 | 3981 | nM | Potency |
| TKC134702 | Q03431 | Parathyroid hormone/parathyroid hormone-related peptide receptor | PTH1R | 7943 | nM | Potency |
| TKC134702 | Q16236 | Nuclear factor erythroid 2-related factor 2 | NFE2L2 | 3663 | nM | Potency |
| TKC134702 | Q99700 | Ataxin-2 | ATXN2 | 19953 | nM | Potency |
| TKC134702 | Q04206 | Transcription factor p65 | RELA | 10 | uM | IC100 |
| TKC134702 | Q962Y6 | Thioredoxin glutathione reductase | TGR | 25119 | nM | Potency |
| TKC134702 | Q9UNA4 | DNA polymerase iota | POLI | 14125 | nM | Potency |
| TKC134702 | O75496 | Geminin | GMNN | 146 | nM | Potency |
| TKC134702 | O89049 | Thioredoxin reductase 1, cytoplasmic | Txnrd1 | 56234 | nM | Potency |
| TKC134702 | Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | APOBEC3G | 562 | nM | Potency |
| TKC134702 | O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | USP1 | 8913 | nM | Potency |
| TKC134702 | P28482 | Mitogen-activated protein kinase 1 | MAPK1 | 31623 | nM | Potency |
| TKC134702 | P83916 | Chromobox protein homolog 1 | CBX1 | 79433 | nM | Potency |
| TKC134702 | Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | EHMT2 | 11220 | nM | Potency |
| TKC134702 | Q96QE3 | ATPase family AAA domain-containing protein 5 | ATAD5 | 5 | nM | Potency |
| TKC134702 | Q92830 | Histone acetyltransferase KAT2A | KAT2A | 25119 | nM | Potency |
| TKC134702 | Q9F4F7 | 4'-phosphopantetheinyl transferase ffp | ffp | 79433 | nM | Potency |
| TKC134702 | O14746 | Telomerase reverse transcriptase | TERT | 4000 | nM | IC50 |
| TKC134702 | P06746 | DNA polymerase beta | POLB | 100000 | nM | Potency |
| TKC134702 | P49798 | Regulator of G-protein signaling 4 | RGS4 | 21192 | nM | Potency |
| TKC134702 | Q9Y253 | DNA polymerase eta | POLH | 89125 | nM | Potency |
| TKC134702 | P51450 | Nuclear receptor ROR-gamma | Rorc | 3162 | nM | Potency |
| TKC134702 | P52333 | Tyrosine-protein kinase JAK3 | JAK3 | 25 | % | Inhibition |
| TKC134702 | P42858 | Huntingtin | HTT | 2239 | nM | Potency |
| TKC134702 | O15118 | NPC intracellular cholesterol transporter 1 | NPC1 | 794 | nM | Potency |
| TKC134702 | P51151 | Ras-related protein Rab-9A | RAB9A | 1000 | nM | Potency |
| TKC134702 | O15264 | Mitogen-activated protein kinase 13 | MAPK13 | 25 | % | Inhibition |
| TKC134702 | Q194T2 | Non-structural protein 1 | NS1 | 4467 | nM | Potency |
| TKC134702 | P17861 | X-box-binding protein 1 | XBP1 | 2430 | nM | IC50 |
| TKC134702 | P35639 | DNA damage-inducible transcript 3 protein | Ddit3 | 2610 | nM | IC50 |
| TKC134702 | P35639 | DNA damage-inducible transcript 3 protein | Ddit3 | 2450 | nM | IC50 |
| TKC134702 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | MDM2 | 420 | nM | EC50 |
| TKC134702 | P06280 | Alpha-galactosidase A | GLA | 39811 | nM | Potency |
| TKC134702 | Q9Y2T6 | G-protein coupled receptor 55 | GPR55 | 2642 | nM | IC50 |
| TKC134702 | P01103 | Transcriptional activator Myb | MYB | 2370 | nM | IC50 |
| TKC134702 | P06492 | Tegument protein VP16 | UL48 | 4374 | nM | IC50 |
| TKC134702 | Q9Y5X4 | Photoreceptor-specific nuclear receptor | NR2E3 | 1921 | nM | IC50 |
| TKC134702 | P30556 | Type-1 angiotensin II receptor | AGTR1 | 18639 | nM | IC50 |
| TKC134702 | P30556 | Type-1 angiotensin II receptor | AGTR1 | 18639 | nM | IC50 |
| TKC134702 | Q8VNN2 | Beta-galactosidase | lacZ | >40000 | nM | EC50 |
| TKC134702 | P35414 | Apelin receptor | APLNR | 21300 | nM | IC50 |
| Uniport ID | Uniport Name | ICD-11 |
|---|---|---|
| P10636 | TAU_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P10636 | TAU_HUMAN | Alzheimer disease [ICD-11: 8A20] |
| P10636 | TAU_HUMAN | Mild neurocognitive disorder [ICD-11: 6D71] |
| P10636 | TAU_HUMAN | Choreiform disorder [ICD-11: 8A01] |
| P10636 | TAU_HUMAN | Parkinsonism [ICD-11: 8A00] |
| P10636 | TAU_HUMAN | Central nervous system disease [ICD-11: 8A04-8D87] |
| P10636 | TAU_HUMAN | Neurodegenerative disorder [ICD-11: 8A20-8A23] |
| P11473 | VDR_HUMAN | Chronic kidney disease [ICD-11: GB61] |
| P11473 | VDR_HUMAN | Hair/hair growth developmental defect [ICD-11: LC30] |
| P11473 | VDR_HUMAN | Hyper-parathyroidism [ICD-11: 5A51] |
| P11473 | VDR_HUMAN | Hypo-parathyroidism [ICD-11: 5A50] |
| P11473 | VDR_HUMAN | Mineral deficiency [ICD-11: 5B5K] |
| P11473 | VDR_HUMAN | Psoriasis [ICD-11: EA90] |
| P11473 | VDR_HUMAN | Vitamin deficiency [ICD-11: 5B55-5B5F] |
| P11473 | VDR_HUMAN | Low bone mass disorder [ICD-11: FB83] |
| P11473 | VDR_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P11473 | VDR_HUMAN | Prostate cancer [ICD-11: 2C82] |
| P11473 | VDR_HUMAN | Prostate disease [ICD-11: GA91] |
| P11473 | VDR_HUMAN | Abnormal micturition [ICD-11: MF50] |
| P11473 | VDR_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P11473 | VDR_HUMAN | Postoperative inflammation [ICD-11: 1A00-CA43] |
| P11473 | VDR_HUMAN | Acne vulgaris [ICD-11: ED80] |
| Q16637 | SMN_HUMAN | Muscular atrophy [ICD-11: 8B61] |
| Q16637 | SMN_HUMAN | Muscular atrophy [ICD-11: 8B61] |
| Q16637 | SMN_HUMAN | Muscular atrophy [ICD-11: 8B61] |
| Q16637 | SMN_HUMAN | Muscular atrophy [ICD-11: 8B61] |
| Q00653 | NFKB2_HUMAN | Ulcerative colitis [ICD-11: DD71] |
| O75874 | IDHC_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| O75874 | IDHC_HUMAN | Liver cancer [ICD-11: 2C12] |
| O75874 | IDHC_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| O75874 | IDHC_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| O75874 | IDHC_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| O75874 | IDHC_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P43220 | GLP1R_HUMAN | Cardiovascular disease [ICD-11: BA00-BE2Z] |
| P43220 | GLP1R_HUMAN | Obesity [ICD-11: 5B80-5B81] |
| P43220 | GLP1R_HUMAN | Type 2 diabetes mellitus [ICD-11: 5A11] |
| P43220 | GLP1R_HUMAN | Type-1/2 diabete [ICD-11: 5A10-5A11] |
| P43220 | GLP1R_HUMAN | Acute diabete complication [ICD-11: 5A2Y] |
| P43220 | GLP1R_HUMAN | Diabetes mellitus [ICD-11: 5A10] |
| P43220 | GLP1R_HUMAN | Dyspepsia [ICD-11: MD92] |
| P43220 | GLP1R_HUMAN | Irritable bowel syndrome [ICD-11: DD91] |
| P43220 | GLP1R_HUMAN | Intracranial injury [ICD-11: NA07] |
| P43220 | GLP1R_HUMAN | Non-alcoholic fatty liver disease [ICD-11: DB92] |
| P84022 | SMAD3_HUMAN | Herpes simplex infection [ICD-11: 1F00] |
| P84022 | SMAD3_HUMAN | Kidney fibrosis [ICD-11: GC01] |
| Q03431 | PTH1R_HUMAN | Low bone mass disorder [ICD-11: FB83] |
| Q03431 | PTH1R_HUMAN | Hypo-parathyroidism [ICD-11: 5A50] |
| Q16236 | NF2L2_HUMAN | Ataxic disorder [ICD-11: 8A03] |
| Q16236 | NF2L2_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| Q16236 | NF2L2_HUMAN | Glaucoma [ICD-11: 9C61] |
| Q16236 | NF2L2_HUMAN | Lung cancer [ICD-11: 2C25] |
| Q16236 | NF2L2_HUMAN | Macular degeneration [ICD-11: 9B75] |
| Q16236 | NF2L2_HUMAN | Melanoma [ICD-11: 2C30] |
| Q16236 | NF2L2_HUMAN | Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z] |
| Q16236 | NF2L2_HUMAN | Pulmonary hypertension [ICD-11: BB01] |
| Q16236 | NF2L2_HUMAN | Subarachnoid haemorrhage [ICD-11: 8B01] |
| Q16236 | NF2L2_HUMAN | Urinary system clinical sympton [ICD-11: MF8Y] |
| Q16236 | NF2L2_HUMAN | Non-alcoholic fatty liver disease [ICD-11: DB92] |
| Q16236 | NF2L2_HUMAN | Alpha-1-antitrypsin deficiency [ICD-11: 5C5A] |
| Q16236 | NF2L2_HUMAN | Motor neuron disease [ICD-11: 8B60] |
| Q16236 | NF2L2_HUMAN | Multiple sclerosis [ICD-11: 8A40] |
| O94782 | UBP1_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P28482 | MK01_HUMAN | Melanoma [ICD-11: 2C30] |
| P28482 | MK01_HUMAN | Pancreatic cancer [ICD-11: 2C10] |
| P28482 | MK01_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P28482 | MK01_HUMAN | Arteries/arterioles disorder [ICD-11: BD52] |
| P28482 | MK01_HUMAN | Allergic/hypersensitivity disorder [ICD-11: 4A80-4A8Z] |
| P28482 | MK01_HUMAN | Transplant rejection [ICD-11: NE84] |
| P28482 | MK01_HUMAN | Mature T-cell lymphoma [ICD-11: 2A90] |
| P28482 | MK01_HUMAN | Rheumatoid arthritis [ICD-11: FA20] |
| Q96KQ7 | EHMT2_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| Q96KQ7 | EHMT2_HUMAN | Postoperative inflammation [ICD-11: 1A00-CA43] |
| Q96KQ7 | EHMT2_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| O14746 | TERT_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| O14746 | TERT_HUMAN | Colorectal cancer [ICD-11: 2B91] |
| O14746 | TERT_HUMAN | Liver cancer [ICD-11: 2C12] |
| O14746 | TERT_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| O14746 | TERT_HUMAN | Pancreatic cancer [ICD-11: 2C10] |
| O14746 | TERT_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| O14746 | TERT_HUMAN | Lung cancer [ICD-11: 2C25] |
| O14746 | TERT_HUMAN | Multiple myeloma [ICD-11: 2A83] |
| O14746 | TERT_HUMAN | Myelodysplastic syndrome [ICD-11: 2A37] |
| O14746 | TERT_HUMAN | Myeloproliferative neoplasm [ICD-11: 2A20] |
| O14746 | TERT_HUMAN | Thrombocytosis [ICD-11: 3B63] |
| O14746 | TERT_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| O14746 | TERT_HUMAN | Melanoma [ICD-11: 2C30] |
| O14746 | TERT_HUMAN | Ovarian cancer [ICD-11: 2C73] |
| O14746 | TERT_HUMAN | Glaucoma [ICD-11: 9C61] |
| O14746 | TERT_HUMAN | Head and neck cancer [ICD-11: 2D42] |
| O14746 | TERT_HUMAN | Liver cancer [ICD-11: 2C12] |
| O14746 | TERT_HUMAN | Brain cancer [ICD-11: 2A00] |
| O14746 | TERT_HUMAN | Prostate cancer [ICD-11: 2C82] |
| O14746 | TERT_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P06746 | DPOLB_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P52333 | JAK3_HUMAN | Rheumatoid arthritis [ICD-11: FA20] |
| P52333 | JAK3_HUMAN | Psoriasis [ICD-11: EA90] |
| P52333 | JAK3_HUMAN | Alopecia [ICD-11: ED70] |
| P52333 | JAK3_HUMAN | Asthma [ICD-11: CA23] |
| P52333 | JAK3_HUMAN | Crohn disease [ICD-11: DD70] |
| P52333 | JAK3_HUMAN | Acquired hypomelanotic disorder [ICD-11: ED63] |
| P52333 | JAK3_HUMAN | Atopic eczema [ICD-11: EA80] |
| P52333 | JAK3_HUMAN | B-cell lymphoma [ICD-11: 2A86] |
| P52333 | JAK3_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| P52333 | JAK3_HUMAN | Pruritus [ICD-11: EC90] |
| P52333 | JAK3_HUMAN | Multiple myeloma [ICD-11: 2A83] |
| P52333 | JAK3_HUMAN | Transplant rejection [ICD-11: NE84] |
| P52333 | JAK3_HUMAN | Diabetes mellitus [ICD-11: 5A10] |
| P52333 | JAK3_HUMAN | Diffuse large B-cell lymphoma [ICD-11: 2A81] |
| P52333 | JAK3_HUMAN | Postoperative inflammation [ICD-11: 1A00-CA43] |
| P42858 | HD_HUMAN | Choreiform disorder [ICD-11: 8A01] |
| P51151 | RAB9A_HUMAN | Fungal infection [ICD-11: 1F29-1F2F] |
| Q00987 | MDM2_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| Q00987 | MDM2_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| Q00987 | MDM2_HUMAN | Myeloproliferative neoplasm [ICD-11: 2A20] |
| Q00987 | MDM2_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| Q00987 | MDM2_HUMAN | Mature B-cell leukaemia [ICD-11: 2A82] |
| Q00987 | MDM2_HUMAN | Myelodysplastic syndrome [ICD-11: 2A37] |
| Q00987 | MDM2_HUMAN | Neuroendocrine carcinoma [ICD-11: 2C34] |
| Q00987 | MDM2_HUMAN | Liposarcoma [ICD-11: 2B59] |
| Q00987 | MDM2_HUMAN | Lung cancer [ICD-11: 2C25] |
| Q00987 | MDM2_HUMAN | Prostate cancer [ICD-11: 2C82] |
| Q00987 | MDM2_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| Q00987 | MDM2_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P06280 | AGAL_HUMAN | Lysosomal disease [ICD-11: 5C56] |
| Q9Y2T6 | GPR55_HUMAN | Attention deficit hyperactivity disorder [ICD-11: 6A05] |
| P30556 | AGTR1_HUMAN | Essential hypertension [ICD-11: BA00] |
| P30556 | AGTR1_HUMAN | Hypertension [ICD-11: BA00-BA04] |
| P30556 | AGTR1_HUMAN | Secondary hypertension [ICD-11: BA04] |
| P30556 | AGTR1_HUMAN | Metabolic disorder [ICD-11: 5C50-5D2Z] |
| P30556 | AGTR1_HUMAN | Myocardial infarction [ICD-11: BA41-BA43] |
| P30556 | AGTR1_HUMAN | Urinary system clinical sympton [ICD-11: MF8Y] |
| P30556 | AGTR1_HUMAN | Heart failure [ICD-11: BD10-BD1Z] |
| P30556 | AGTR1_HUMAN | Hypotension [ICD-11: BA20-BA21] |
| P30556 | AGTR1_HUMAN | Alzheimer disease [ICD-11: 8A20] |
| P30556 | AGTR1_HUMAN | Arteries/arterioles disorder [ICD-11: BD52] |
| P30556 | AGTR1_HUMAN | Essential hypertension [ICD-11: BA00] |
| P30556 | AGTR1_HUMAN | Hypertension [ICD-11: BA00-BA04] |
| P30556 | AGTR1_HUMAN | Secondary hypertension [ICD-11: BA04] |
| P30556 | AGTR1_HUMAN | Metabolic disorder [ICD-11: 5C50-5D2Z] |
| P30556 | AGTR1_HUMAN | Myocardial infarction [ICD-11: BA41-BA43] |
| P30556 | AGTR1_HUMAN | Urinary system clinical sympton [ICD-11: MF8Y] |
| P30556 | AGTR1_HUMAN | Heart failure [ICD-11: BD10-BD1Z] |
| P30556 | AGTR1_HUMAN | Hypotension [ICD-11: BA20-BA21] |
| P30556 | AGTR1_HUMAN | Alzheimer disease [ICD-11: 8A20] |
| P30556 | AGTR1_HUMAN | Arteries/arterioles disorder [ICD-11: BD52] |
| P35414 | APJ_HUMAN | Heart failure [ICD-11: BD10-BD1Z] |