Basic Information

Terpenoid ID TKC038268
Chirality TKC134702
Cell line 0
Protein target 17
DiseaseNCIT 0
ORDO 0
ICD 45

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC038268 HepG2 22387.0 nM Potency C3728 Orphanet_449
TKC038268 HEK293 1259.0 nM Potency
TKC038268 RAW264.7 RAW264 1100.0 nM IC50 C21604

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC038268 P11473 Vitamin D3 receptor VDR 89125 nM Potency
TKC038268 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 581 nM Potency
TKC038268 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 1836 nM Potency
TKC038268 P43220 Glucagon-like peptide 1 receptor GLP1R 355 nM Potency
TKC038268 P84022 Mothers against decapentaplegic homolog 3 SMAD3 3162 nM Potency
TKC038268 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 5805 nM Potency
TKC038268 Q99700 Ataxin-2 ATXN2 37686 nM Potency
TKC038268 Q9UNA4 DNA polymerase iota POLI 22387 nM Potency
TKC038268 O75496 Geminin GMNN 581 nM Potency
TKC038268 P01215 Glycoprotein hormones alpha chain CGA 316 nM Potency
TKC038268 P38398 Breast cancer type 1 susceptibility protein BRCA1 1259 nM Potency
TKC038268 Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G APOBEC3G 562 nM Potency
TKC038268 P49798 Regulator of G-protein signaling 4 RGS4 35481 nM Potency
TKC038268 Q9Y253 DNA polymerase eta POLH 31623 nM Potency
TKC038268 Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F APOBEC3F 562 nM Potency
TKC038268 P06492 Tegument protein VP16 UL48 10519 nM IC50
TKC038268 Q9Y5X4 Photoreceptor-specific nuclear receptor NR2E3 2737 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P11473 VDR_HUMAN Chronic kidney disease [ICD-11: GB61]
P11473 VDR_HUMAN Hair/hair growth developmental defect [ICD-11: LC30]
P11473 VDR_HUMAN Hyper-parathyroidism [ICD-11: 5A51]
P11473 VDR_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P11473 VDR_HUMAN Mineral deficiency [ICD-11: 5B5K]
P11473 VDR_HUMAN Psoriasis [ICD-11: EA90]
P11473 VDR_HUMAN Vitamin deficiency [ICD-11: 5B55-5B5F]
P11473 VDR_HUMAN Low bone mass disorder [ICD-11: FB83]
P11473 VDR_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11473 VDR_HUMAN Prostate cancer [ICD-11: 2C82]
P11473 VDR_HUMAN Prostate disease [ICD-11: GA91]
P11473 VDR_HUMAN Abnormal micturition [ICD-11: MF50]
P11473 VDR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11473 VDR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P11473 VDR_HUMAN Acne vulgaris [ICD-11: ED80]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P43220 GLP1R_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P43220 GLP1R_HUMAN Obesity [ICD-11: 5B80-5B81]
P43220 GLP1R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P43220 GLP1R_HUMAN Type-1/2 diabete [ICD-11: 5A10-5A11]
P43220 GLP1R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P43220 GLP1R_HUMAN Diabetes mellitus [ICD-11: 5A10]
P43220 GLP1R_HUMAN Dyspepsia [ICD-11: MD92]
P43220 GLP1R_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P43220 GLP1R_HUMAN Intracranial injury [ICD-11: NA07]
P43220 GLP1R_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]