Basic Information
| Terpenoid ID | TKC151761 |
|
| Chirality | TKC014820 | |
| Cell line | 0 | |
| Protein target | 20 | |
| DiseaseNCIT | 0 | |
| ORDO | 0 | |
| ICD | 21 |
| Terpenoid ID | TKC151761 |
|
| Chirality | TKC014820 | |
| Cell line | 0 | |
| Protein target | 20 | |
| DiseaseNCIT | 0 | |
| ORDO | 0 | |
| ICD | 21 |
| ID | Cell Line | Synonyms | Value | Unit | Type | NCIt | ORDO |
|---|---|---|---|---|---|---|---|
| TKC151761 | B16 | B-16; B16 melanoma; B16 subline B78; B78 | 8.0 | nM | IC50 | C21790 | |
| TKC151761 | SK-OV-3 | SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 | 5.0 | nM | IC50 | C7978 | |
| TKC151761 | HCT-116 | HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 | 1.0 | nM | IC50 | C4910 | |
| TKC151761 | M109 | Madison 109; Madison lung; Madison; MADISON LUNG TA-109; MAD109 | 166.0 | % | T/C | C21769 | |
| TKC151761 | J774.2 | J774 clone 2 | 31.0 | nM | IC50 | C134780 | |
| TKC151761 | DU-145 | DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 | 1.0 | nM | ED50 | C4863 | |
| TKC151761 | HT-29 | HT 29; HT29 | 50.0 | nM | IC50 | C4349 | |
| TKC151761 | PC-3 | PC3; PC.3 | 3.0 | nM | IC50 | C4863 | |
| TKC151761 | CCD 19Lu | CCD 19Lu; CCD-19LU; CCD19-Lu; CCD19Lu | 2.0 | ug.mL-1 | IC50 | ||
| TKC151761 | NSCLC | NSCLCN6 | 4.0 | nM | IC50 | C3493 | |
| TKC151761 | Lewis lung carcinoma cell line | 61.0 | nM | IC50 | |||
| TKC151761 | YOSHIDA | YS; YOSHIDA; Yoshida ascites sarcoma cell; Ascites sarcoma of Nagasaki strain | 8.0 | nM | IC50 | C60505 | |
| TKC151761 | WALKER | Walker256-TC | 150.0 | nM | IC50 | C64011 | |
| TKC151761 | PC-12 | PC 12; PC12 | 1.0 | ug.mL-1 | GI50 | C5650 | |
| TKC151761 | HCT-15 | HCT-15; HCT.15; HCT15 | 79.0 | nM | IC50 | C4349 | |
| TKC151761 | MDA-MB-435 | MDA-MB435; MDAMB435; MDA.MB.435; MDA-435; MDA 435; MDA435; MD Anderson-Metastatic Breast-435 | 1.0 | nM | IC50 | C3802 | |
| TKC151761 | MCF7S | 2.0 | nM | IC50 | |||
| TKC151761 | MCF7R | MCF7R | 299.0 | nM | IC50 | C4194 | |
| TKC151761 | KB | KB (HeLa derivative); HeLa-KB; Strain KB | 2.0 | nM | ED50 | C27677 | |
| TKC151761 | SF-268 | SF-268; SF.268; SF 268 | 10.0 | nM | IC50 | C60781 | Orphanet_94 |
| TKC151761 | RKO | 10.0 | nM | IC50 | C4910 | ||
| TKC151761 | LT12 tumor cell line | LT-12; IPC-81 | 6.0 | nM | IC50 | C60428 | |
| TKC151761 | P388/ADR | 30.0 | nM | IC50 | C21602 | ||
| TKC151761 | K562 | K562; K.562; K 562; KO; GM05372; GM05372E | 14.0 | nM | EC50 | C9110 | Orphanet_521 |
| TKC151761 | A121 | A121; A121(Primary) | 6.0 | nM | IC50 | C9192 | Orphanet_213512 |
| TKC151761 | EL4 | EL-4; EL 4; E.L.4 | 1.0 | ug.mL-1 | IC50 | C21925 | |
| TKC151761 | BeWo | BEWO; Be Wo; Be-Wo | 7.0 | ug.mL-1 | IC50 | C4646 | Orphanet_99926 |
| TKC151761 | A2780 | A-2780; 2780; A2780S; A2780par | 1.0 | nM | IC50 | C7979 | Orphanet_454723 |
| TKC151761 | MOLT-4 | Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D | 2.0 | nM | IC50 | C9142 | Orphanet_99861 |
| TKC151761 | SR | SR-786; SR786 | 3.0 | nM | GI50 | C37193 | Orphanet_300895 |
| TKC151761 | HOP-62 | HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 | 16.0 | nM | GI50 | C3512 | |
| TKC151761 | NCI-H522 | NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 | 3.0 | nM | GI50 | C3512 | |
| TKC151761 | COLO 205 | Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 | 3.0 | nM | GI50 | C4349 | |
| TKC151761 | HCC 2998 | HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 | 3.0 | nM | GI50 | C4349 | |
| TKC151761 | KM12 | KM-12; KM.12 | 3.0 | nM | GI50 | C4910 | |
| TKC151761 | SF-295 | SF-295; SF.295; SF 295 | 16.0 | nM | GI50 | C3058 | Orphanet_360 |
| TKC151761 | SF-539 | SF-539; SF-539 BT; SF.539; SF 539 | 3.0 | nM | GI50 | C3796 | Orphanet_251576 |
| TKC151761 | SNB-19 | SNB.19; SNB19; Surgical Neurology Branch-19 | 10.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC151761 | U-251 | U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) | 4.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC151761 | M14 | M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 | 10.0 | nM | GI50 | C3802 | |
| TKC151761 | SK-MEL-2 | SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 | 7.0 | nM | IC50 | C3224 | |
| TKC151761 | SK-MEL-5 | SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel | 4.0 | nM | GI50 | C3510 | |
| TKC151761 | UACC-62 | UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 | 4.0 | nM | GI50 | C3224 | |
| TKC151761 | OVCAR-3 | Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 | 1.0 | nM | IC50 | C105555 | |
| TKC151761 | OVCAR-8 | OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 | 5.0 | nM | GI50 | C105555 | |
| TKC151761 | 786-0 | 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT | -7.0 | nM | Log IC50 | C9385 | Orphanet_217071 |
| TKC151761 | RXF 393 | RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL | 8.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC151761 | UO-31 | UO.31; UO31; U031 | 1000.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC151761 | NCI/ADR-RES | NCI/ADR-RES; NCI.ADR.RES; NCIADR.RES; NCI/ADRRES; NCIADRRES; ADR-RES; MCF-7/ADR; MCF-7/ADR-RES; MCF-7/AdrR; MCF-7/Adr; MCF-7/adr; MCF-7ADR; MCF7-ADR; MCF7ADR; OVCAR-8/ADR; OVCAR8/ADR | 10000.0 | nM | EC50 | C105555 | |
| TKC151761 | Hs-578T | HS 578T; Hs-578T; HS-578T; Hs_578t; Hs-578-T; HS-578-T; Hs 578.T; HS578T; Hs578T; Hs578t; HS0578T; 578T; HS578; Hs578; Homo sapiens No. 578, tumor cells | -8.0 | nM | Log IC50 | C4194 | |
| TKC151761 | BT-549 | BT 549; BT.549; BT549 | 6.0 | nM | GI50 | C4194 | |
| TKC151761 | J774 | J-774 | 15.0 | nM | IC50 | C134780 | |
| TKC151761 | NCI-H1299 | H1299; H-1299; NCIH1299 | 15.0 | nM | IC50 | C4450 | |
| TKC151761 | MES-SA | MESSA | 5.0 | nM | IC50 | C6339 | Orphanet_213620 |
| TKC151761 | EMT6 | EMT-6; Experimental Mammary Tumour-6 | 9.0 | nM | IC50 | C21678 | |
| TKC151761 | OV-1063 | Ov-1063; OV 1063; OV1063; 0V-1063 | 15.0 | nM | IC50 | C5228 | |
| TKC151761 | MEXF514 | MEXF514L; MEXF 514; MEXF514 | 1030.0 | nM | IC50 | C3224 | |
| TKC151761 | RXF 944 | RXF944L; RXF 944; RXF944 | 50.0 | nM | IC50 | C9385 | Orphanet_217071 |
| TKC151761 | Coronary artery smooth muscle cell line | 1000.0 | nM | IC50 | |||
| TKC151761 | 1A9 | A2780/1A9; A2780(1A9); 1A9 | 1.0 | nM | GI50 | C7979 | Orphanet_454723 |
| TKC151761 | 1A9/ptx-10 | A2780/1A9; A2780(1A9); 1A9 | 64.0 | nM | GI50 | C7979 | Orphanet_454723 |
| TKC151761 | DLD-1 | DLD 1; DLD1; CoCL3 | 75.0 | nM | EC50 | C4349 | |
| TKC151761 | U-937 | U937; U 937 | 1.0 | nM | IC50 | C8263 | Orphanet_514 |
| TKC151761 | KB 3-1 | KB 3-1; KB3-1; KB31 | 2.0 | nM | IC50 | C27677 | |
| TKC151761 | HeLa | HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri | 8.0 | nM | IC50 | C27677 | |
| TKC151761 | SW480 | SW-480; SW 480; SW480E | 312.0 | nM | IC50 | C4349 | |
| TKC151761 | A204 | A204 | -9.0 | nM | Log IC50 | C8971 | Orphanet_99757 |
| TKC151761 | BXPC-3 | BxPc-3; BXPC-3; Bx-PC3; BXPC3; BxPC3; BxPc3; Biopsy xenograft of Pancreatic Carcinoma line-3 | -9.0 | nM | Log IC50 | C9120 | |
| TKC151761 | MIA PaCa-2 | MIA-PaCa-2; MIA-PACA-2; MIA-Pa-Ca-2; MIA Paca2; MIA PaCa2; MiaPaCa-2; MIAPACA-2; MiaPaca.2; MiaPaCa2; Miapaca2; MIAPaCa2; MIAPACA2; Mia PACA 2; MIAPaCa-2; PaCa2; MiaPaCa | -9.0 | nM | Log IC50 | C9120 | |
| TKC151761 | CFPAC-1 | CFPac-1; CF PAC-1; CF-PAC1; CF-Pac1; CF Pac1; CFPAC1; CFPac1; CFPAC | -8.0 | nM | Log IC50 | C2975 | Orphanet_586 |
| TKC151761 | PANC-1 | Panc-1; PANC.1; Panc 1; PanC1; Panc1; PANC1; Panc-1-P | -5.0 | nM | Log IC50 | C9120 | |
| TKC151761 | ZR-75-1 | Zr-75-1; ZR751; ZR75-1; ZR75.1; ZR75_1 | 308.0 | nM | IC50 | C4194 | |
| TKC151761 | SK-MEL-28 | SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 | -8.0 | nM | Log IC50 | C3510 | |
| TKC151761 | Malme-3M | MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer | -6.0 | nM | Log IC50 | C3224 | |
| TKC151761 | LoVo | LOVO | -7.0 | nM | Log IC50 | C4349 | |
| TKC151761 | T47D | 30.0 | nM | EC50 | C4194 | ||
| TKC151761 | U-87 MG | 3.0 | ug.mL-1 | IC50 | C3058 | Orphanet_360 | |
| TKC151761 | H4 | H-4 | -7.0 | nM | Log IC50 | C60781 | Orphanet_94 |
| TKC151761 | T98G | T 98 G; T-98G; T98 G; T98-G | -9.0 | nM | Log IC50 | C3058 | Orphanet_360 |
| TKC151761 | A-427 | A427; A427N | -8.0 | nM | Log IC50 | C3512 | |
| TKC151761 | T-24 | T-24; T 24 | -9.0 | nM | Log IC50 | C4912 | |
| TKC151761 | HT1197 | HT 1197; HT1197; HT 1197.T | -5.0 | nM | Log IC50 | C7899 | |
| TKC151761 | LNCaP | LNCAP; LNCap; Ln-Cap; Lymph Node Carcinoma of the prostate | 2.0 | nM | IC50 | C4863 | |
| TKC151761 | BT-20 | BT 20; BT20 | -9.0 | nM | Log IC50 | C4194 | |
| TKC151761 | A704 | A.704; A704 | -5.0 | nM | Log IC50 | C9385 | Orphanet_217071 |
| TKC151761 | ACHN | 25.0 | nM | IC50 | C6975 | Orphanet_319298 | |
| TKC151761 | CAKI-2 | CAKI-2; CaKi-2; caki-2; CAKI 2; Caki 2; Caki2; CAKI2 | -9.0 | nM | Log IC50 | C6975 | Orphanet_319298 |
| TKC151761 | FaDu | FaDU; FADU | -9.0 | nM | Log IC50 | C4043 | Orphanet_494547 |
| TKC151761 | MDA-MB-231 | MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 | -5.0 | nM | Log IC50 | C5214 | |
| TKC151761 | HT-1080 | Ht-1080; HT 1080; HT1080; HT 1080.T | -9.0 | nM | Log IC50 | C3043 | Orphanet_2030 |
| TKC151761 | LOX IMVI | LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX | 17.0 | nM | IC50 | C3802 | |
| TKC151761 | PPC-1 | Primary Prostate Carcinoma-1; Specimen P-3 | 3.0 | nM | IC50 | C4863 | |
| TKC151761 | TSU | 2.0 | nM | IC50 | C129857 | Orphanet_502363 | |
| TKC151761 | MCF7-DOX | 585.0 | nM | IC50 | C4194 | ||
| TKC151761 | A-431 | A431; A431/P | 9.0 | nM | EC50 | C4819 | |
| TKC151761 | HepG2 | 300.0 | nM | IC50 | C3728 | Orphanet_449 | |
| TKC151761 | NCI-H295R | NCI H295R; NCIH295R; H295R; H-295R; H295R-S1 | 80.0 | nM | IC50 | C9325 | Orphanet_1501 |
| TKC151761 | PT-45 | PT 45; PT-45 | 5.0 | nM | IC50 | C9120 | |
| TKC151761 | 4T1 | 4T1-A; 4T1.0; 4T1/WT | 200.0 | nM | IC50 | C21678 | |
| TKC151761 | BNL | 200.0 | nM | IC50 | |||
| TKC151761 | SiHa | Siha; SIHA | 1.0 | ug.mL-1 | IC50 | C27676 | Orphanet_213767 |
| TKC151761 | MX1 | MX1; MXI | 23.0 | nM | IC50 | C4872 | |
| TKC151761 | Panel (12 tumour cell lines) | 1.0 | nM | IC70 | |||
| TKC151761 | NCI-H630 | H630; H-630; NCIH630 | 24.0 | nM | IC50 | ||
| TKC151761 | MKN-45 | MKN-45; MKN 45 | 1.0 | nM | IC50 | C4004 | |
| TKC151761 | NIH3T3 | NIH/3T3; NIH-3T3; NIH3T3; 3T3; 3T3NIH; 3T3-Swiss; Swiss-3T3; Swiss/3T3; Swiss 3T3; Swiss3T3 | 1290.0 | nM | IC50 | ||
| TKC151761 | NCI-H69 | NCI-H-69; NCI H69; H69; H-69; NCIH69; NCI-HUT-69; H69/P; NCI-H69C; H69C; H69c | 2.0 | nM | IC50 | C4917 | Orphanet_70573 |
| TKC151761 | M21 | UCLA-SO-M21; UCLA SO M21 | 37.0 | nM | GI50 | C3224 | |
| TKC151761 | 1A9/ptx-22 | A2780/1A9; A2780(1A9); 1A9 | 51.0 | nM | GI50 | C7979 | Orphanet_454723 |
| TKC151761 | NCI-H322M | NCI.H322M; H322M; H-322M; H-322m | 13.0 | nM | GI50 | C2923 | |
| TKC151761 | RPMI-8226 | RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson | 2.0 | nM | GI50 | C3242 | Orphanet_29073 |
| TKC151761 | SNB-75 | SNB.75; SNB75; Surgical Neurology Branch-75 | 4.0 | nM | GI50 | C3058 | Orphanet_360 |
| TKC151761 | UACC-257 | UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 | 40.0 | nM | GI50 | C3224 | |
| TKC151761 | U-937/GTB | U-937-GTB; U-937/GTB; U937/GTB; U937-GTB | 6.0 | nM | IC50 | C8263 | Orphanet_514 |
| TKC151761 | RPTEC | 1.0 | nM | IC50 | |||
| TKC151761 | HEK293 | 10.0 | nM | IC50 | |||
| TKC151761 | OE19 | OE-19; JROECL 19; JROECL19; OEC19 | 400.0 | nM | IC50 | C4025 | Orphanet_99976 |
| TKC151761 | OE33 | OE-33; JROECL 33; JROECL33; OEC33 | 200.0 | nM | IC50 | C7027 | Orphanet_99976 |
| TKC151761 | SW-620 | SW-620; SW 620; SW.620 | 41.0 | % | Inhibition | C4349 | |
| TKC151761 | BGC-823 | BGC823 | 1150.0 | nM | IC50 | C27677 |
| ID | Uniport | Pref_name | Gene name | value | unit | type |
|---|---|---|---|---|---|---|
| TKC151761 | P68371 | Tubulin beta-4B chain | TUBB4B | 31 | nM | EC50 |
| TKC151761 | Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | SLCO1B3 | 260 | nM | IC50 |
| TKC151761 | Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | SLCO1B1 | 280 | nM | IC50 |
| TKC151761 | P08183 | ATP-dependent translocase ABCB1 | ABCB1 | 700 | nM | Km |
| TKC151761 | P08183 | ATP-dependent translocase ABCB1 | ABCB1 | 53900 | nM | IC50 |
| TKC151761 | P08183 | ATP-dependent translocase ABCB1 | ABCB1 | 2596 | nM | IC50 |
| TKC151761 | P08183 | ATP-dependent translocase ABCB1 | ABCB1 | 2600 | nM | IC50 |
| TKC151761 | P00533 | Epidermal growth factor receptor | EGFR | >10000 | nM | IC50 |
| TKC151761 | Q6B856 | Tubulin beta-2B chain | TUBB2B | 1 | uM | ED50 |
| TKC151761 | Q6B856 | Tubulin beta-2B chain | TUBB2B | 830 | nM | EC50 |
| TKC151761 | P10809 | 60 kDa heat shock protein, mitochondrial | HSPD1 | >100000 | nM | IC50 |
| TKC151761 | Q07817 | Bcl-2-like protein 1 | BCL2L1 | >10000 | nM | GI50 |
| TKC151761 | P12931 | Proto-oncogene tyrosine-protein kinase Src | SRC | >10000 | nM | IC50 |
| TKC151761 | O15438 | ATP-binding cassette sub-family C member 3 | ABCC3 | 133000 | nM | IC50 |
| TKC151761 | O15439 | ATP-binding cassette sub-family C member 4 | ABCC4 | 133000 | nM | IC50 |
| TKC151761 | O95342 | Bile salt export pump | ABCB11 | 15000 | nM | IC50 |
| TKC151761 | O95342 | Bile salt export pump | ABCB11 | 15000 | nM | IC50 |
| TKC151761 | O95342 | Bile salt export pump | ABCB11 | 24400 | nM | IC50 |
| TKC151761 | O95342 | Bile salt export pump | ABCB11 | 26800 | nM | IC50 |
| TKC151761 | Q92887 | ATP-binding cassette sub-family C member 2 | ABCC2 | 133000 | nM | IC50 |
| TKC151761 | P22309 | UDP-glucuronosyltransferase 1A1 | UGT1A1 | 20000 | nM | IC50 |
| TKC151761 | P22310 | UDP-glucuronosyltransferase 1A4 | UGT1A4 | 4900 | nM | IC50 |
| TKC151761 | P19224 | UDP-glucuronosyltransferase 1-6 | UGT1A6 | 74000 | nM | IC50 |
| TKC151761 | P0DPI0 | Botulinum neurotoxin type A | botA | 5200 | nM | IC50 |
| TKC151761 | P21447 | ATP-dependent translocase ABCB1 | Abcb1a | 327000 | nM | IC50 |
| TKC151761 | P05106 | Integrin beta-3 | ITGB3 | 34 | nM | IC50 |
| TKC151761 | P02554 | Tubulin beta chain | 520 | nM | EC50 | |
| TKC151761 | Q16762 | Thiosulfate sulfurtransferase | TST | >100000 | nM | IC50 |
| TKC151761 | P10415 | Apoptosis regulator Bcl-2 | BCL2 | >10000 | nM | GI50 |
| TKC151761 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | NOD2 | 7943 | nM | IC50 |
| TKC151761 | P27169 | Serum paraoxonase/arylesterase 1 | PON1 | 42000 | nM | IC50 |
| TKC151761 | P36537 | UDP-glucuronosyltransferase 2B10 | UGT2B10 | >3.00e+5 | nM | IC50 |
| TKC151761 | Q25270 | Beta-tubulin | beta-tubulin | 80 | % | Inhibition |
| TKC151761 | A3EZI9 | Genome polyprotein | NS3 | >1000 | nM | IC50 |
| TKC151761 | P00519 | Tyrosine-protein kinase ABL1 | ABL1 | >10000 | nM | IC50 |
| TKC151761 | P11362 | Fibroblast growth factor receptor 1 | FGFR1 | >10000 | nM | IC50 |
| TKC151761 | Q12866 | Tyrosine-protein kinase Mer | MERTK | 4900 | nM | IC50 |
| TKC151761 | Q13509 | Tubulin beta-3 chain | TUBB3 | 7.7 | nM | IC50 |
| Uniport ID | Uniport Name | ICD-11 |
|---|---|---|
| P08183 | MDR1_HUMAN | Lung cancer [ICD-11: 2C25] |
| P08183 | MDR1_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P08183 | MDR1_HUMAN | Bacterial infection [ICD-11: 1A00-1C4Z] |
| P08183 | MDR1_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P08183 | MDR1_HUMAN | Adrenal cancer [ICD-11: 2D11] |
| P08183 | MDR1_HUMAN | Ovarian cancer [ICD-11: 2C73] |
| P08183 | MDR1_HUMAN | Lung cancer [ICD-11: 2C25] |
| P08183 | MDR1_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P08183 | MDR1_HUMAN | Bacterial infection [ICD-11: 1A00-1C4Z] |
| P08183 | MDR1_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P08183 | MDR1_HUMAN | Adrenal cancer [ICD-11: 2D11] |
| P08183 | MDR1_HUMAN | Ovarian cancer [ICD-11: 2C73] |
| P08183 | MDR1_HUMAN | Lung cancer [ICD-11: 2C25] |
| P08183 | MDR1_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P08183 | MDR1_HUMAN | Bacterial infection [ICD-11: 1A00-1C4Z] |
| P08183 | MDR1_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P08183 | MDR1_HUMAN | Adrenal cancer [ICD-11: 2D11] |
| P08183 | MDR1_HUMAN | Ovarian cancer [ICD-11: 2C73] |
| P08183 | MDR1_HUMAN | Lung cancer [ICD-11: 2C25] |
| P08183 | MDR1_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P08183 | MDR1_HUMAN | Bacterial infection [ICD-11: 1A00-1C4Z] |
| P08183 | MDR1_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P08183 | MDR1_HUMAN | Adrenal cancer [ICD-11: 2D11] |
| P08183 | MDR1_HUMAN | Ovarian cancer [ICD-11: 2C73] |
| P00533 | EGFR_HUMAN | Non-small cell lung cancer [ICD-11: 2C25] |
| P00533 | EGFR_HUMAN | Lung cancer [ICD-11: 2C25] |
| P00533 | EGFR_HUMAN | Head and neck cancer [ICD-11: 2D42] |
| P00533 | EGFR_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P00533 | EGFR_HUMAN | Angina pectoris [ICD-11: BA40] |
| P00533 | EGFR_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| P00533 | EGFR_HUMAN | Colon cancer [ICD-11: 2B90] |
| P00533 | EGFR_HUMAN | Colorectal cancer [ICD-11: 2B91] |
| P00533 | EGFR_HUMAN | Diabetic foot ulcer [ICD-11: BD54] |
| P00533 | EGFR_HUMAN | Head and neck cancer [ICD-11: 2D42] |
| P00533 | EGFR_HUMAN | Hepatitis virus infection [ICD-11: 1E50-1E51] |
| P00533 | EGFR_HUMAN | Ischemia [ICD-11: 8B10-8B11] |
| P00533 | EGFR_HUMAN | Liver cancer [ICD-11: 2C12] |
| P00533 | EGFR_HUMAN | Lung cancer [ICD-11: 2C25] |
| P00533 | EGFR_HUMAN | Melanoma [ICD-11: 2C30] |
| P00533 | EGFR_HUMAN | Myelodysplastic syndrome [ICD-11: 2A37] |
| P00533 | EGFR_HUMAN | Pancreatic cancer [ICD-11: 2C10] |
| P00533 | EGFR_HUMAN | Renal cell carcinoma [ICD-11: 2C90] |
| P00533 | EGFR_HUMAN | Skin postprocedural disorder [ICD-11: EL8Y] |
| P00533 | EGFR_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P00533 | EGFR_HUMAN | Stomach cancer [ICD-11: 2B72] |
| P00533 | EGFR_HUMAN | Unspecific body region injury [ICD-11: ND56] |
| P00533 | EGFR_HUMAN | Urethral cancer [ICD-11: 2C93] |
| P00533 | EGFR_HUMAN | Brain cancer [ICD-11: 2A00] |
| P00533 | EGFR_HUMAN | Hypopharyngeal cancer [ICD-11: 2B6D] |
| P00533 | EGFR_HUMAN | Nasopharyngeal cancer [ICD-11: 2B6B] |
| P00533 | EGFR_HUMAN | Metastatic biliary tract neoplasms [ICD-11: 2C14-2C17] |
| P00533 | EGFR_HUMAN | Chronic pain [ICD-11: MG30] |
| P00533 | EGFR_HUMAN | Lymphoma [ICD-11: 2A80-2A86] |
| P00533 | EGFR_HUMAN | Malignant mesenchymal neoplasm [ICD-11: 2B5D-2B5Y] |
| P00533 | EGFR_HUMAN | Non-small cell lung cancer [ICD-11: 2C25] |
| P00533 | EGFR_HUMAN | Intracerebral haemorrhage [ICD-11: 8B00] |
| P00533 | EGFR_HUMAN | Mature B-cell leukaemia [ICD-11: 2A82] |
| P00533 | EGFR_HUMAN | Metastatic lymph node neoplasm [ICD-11: 2D60] |
| P00533 | EGFR_HUMAN | Spinal cord/cranial nerve neoplasm [ICD-11: 2A02] |
| P00533 | EGFR_HUMAN | Testicular cancer [ICD-11: 2C80] |
| P00533 | EGFR_HUMAN | Esophageal cancer [ICD-11: 2B70] |
| P00533 | EGFR_HUMAN | Psoriasis [ICD-11: EA90] |
| P00533 | EGFR_HUMAN | Digestive system disease [ICD-11: DE2Z] |
| P00533 | EGFR_HUMAN | Cerebral ischaemia [ICD-11: 8B1Z] |
| P00533 | EGFR_HUMAN | Cryptosporidiosis [ICD-11: 1A32] |
| P00533 | EGFR_HUMAN | Diffuse large B-cell lymphoma [ICD-11: 2A81] |
| P00533 | EGFR_HUMAN | Gram-positive bacterial infection [ICD-11: 1B74-1F40] |
| P00533 | EGFR_HUMAN | Brain cancer [ICD-11: 2A00] |
| P00533 | EGFR_HUMAN | Liver cancer [ICD-11: 2C12] |
| P00533 | EGFR_HUMAN | Lung cancer [ICD-11: 2C25] |
| P00533 | EGFR_HUMAN | Pancreatic cancer [ICD-11: 2C10] |
| P10809 | CH60_HUMAN | Diabetes mellitus [ICD-11: 5A10] |
| Q07817 | B2CL1_HUMAN | Mature B-cell leukaemia [ICD-11: 2A82] |
| Q07817 | B2CL1_HUMAN | Myeloproliferative neoplasm [ICD-11: 2A20] |
| Q07817 | B2CL1_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| Q07817 | B2CL1_HUMAN | Lung cancer [ICD-11: 2C25] |
| Q07817 | B2CL1_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| Q07817 | B2CL1_HUMAN | Mature T-cell lymphoma [ICD-11: 2A90] |
| P12931 | SRC_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| P12931 | SRC_HUMAN | Ischemia [ICD-11: 8B10-8B11] |
| P12931 | SRC_HUMAN | Multiple myeloma [ICD-11: 2A83] |
| P12931 | SRC_HUMAN | Myeloproliferative neoplasm [ICD-11: 2A20] |
| P12931 | SRC_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P12931 | SRC_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P12931 | SRC_HUMAN | BCR-ABL1-negative chronic myeloid leukaemia [ICD-11: 2A41] |
| P12931 | SRC_HUMAN | Brain cancer [ICD-11: 2A00] |
| P12931 | SRC_HUMAN | Cervical cancer [ICD-11: 2C77] |
| P12931 | SRC_HUMAN | Endometrial cancer [ICD-11: 2C76] |
| P12931 | SRC_HUMAN | Epidermal dysplasias [ICD-11: EK90] |
| P12931 | SRC_HUMAN | Fallopian tube cancer [ICD-11: 2C74] |
| P12931 | SRC_HUMAN | Gastrointestinal stromal tumour [ICD-11: 2B5B] |
| P12931 | SRC_HUMAN | Leiomyosarcoma [ICD-11: 2B58] |
| P12931 | SRC_HUMAN | Malignant digestive organ neoplasm [ICD-11: 2C11] |
| P12931 | SRC_HUMAN | Metastatic digestive system neoplasm [ICD-11: 2D8Y] |
| P12931 | SRC_HUMAN | Motor neuron disease [ICD-11: 8B60] |
| P12931 | SRC_HUMAN | Multiple sclerosis [ICD-11: 8A40] |
| P12931 | SRC_HUMAN | Ovarian cancer [ICD-11: 2C73] |
| P12931 | SRC_HUMAN | Pancreatic cancer [ICD-11: 2C10] |
| P12931 | SRC_HUMAN | Peritoneal cancer [ICD-11: 2C51] |
| P12931 | SRC_HUMAN | Sarcoma [ICD-11: 2A60-2C35] |
| P12931 | SRC_HUMAN | Synovial sarcoma [ICD-11: 2B5A] |
| P12931 | SRC_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| P12931 | SRC_HUMAN | Osteosarcoma [ICD-11: 2B51] |
| P12931 | SRC_HUMAN | Cardiovascular disease [ICD-11: BA00-BE2Z] |
| P12931 | SRC_HUMAN | Mature B-cell leukaemia [ICD-11: 2A82] |
| P12931 | SRC_HUMAN | Parkinsonism [ICD-11: 8A00] |
| P12931 | SRC_HUMAN | Postoperative inflammation [ICD-11: 1A00-CA43] |
| P12931 | SRC_HUMAN | Low bone mass disorder [ICD-11: FB83] |
| P12931 | SRC_HUMAN | Gram-positive bacterial infection [ICD-11: 1B74-1F40] |
| P12931 | SRC_HUMAN | Nasopharyngeal cancer [ICD-11: 2B6B] |
| P22309 | UD11_HUMAN | Inborn porphyrin/heme metabolism error [ICD-11: 5C58] |
| P0DPI0 | BXA1_CLOBO | Acne vulgaris [ICD-11: ED80] |
| P0DPI0 | BXA1_CLOBO | Ataxic disorder [ICD-11: 8A03] |
| P0DPI0 | BXA1_CLOBO | Clostridium difficile enterocolitis [ICD-11: 1A04] |
| P05106 | ITB3_HUMAN | Cardiovascular disease [ICD-11: BA00-BE2Z] |
| P05106 | ITB3_HUMAN | Chronic arterial occlusive disease [ICD-11: BD4Z] |
| P10415 | BCL2_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| P10415 | BCL2_HUMAN | Mature B-cell leukaemia [ICD-11: 2A82] |
| P10415 | BCL2_HUMAN | Motor neuron disease [ICD-11: 8B60] |
| P10415 | BCL2_HUMAN | Ovarian cancer [ICD-11: 2C73] |
| P10415 | BCL2_HUMAN | Pancreatic cancer [ICD-11: 2C10] |
| P10415 | BCL2_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P10415 | BCL2_HUMAN | Stomach cancer [ICD-11: 2B72] |
| P10415 | BCL2_HUMAN | Melanoma [ICD-11: 2C30] |
| P10415 | BCL2_HUMAN | Multiple myeloma [ICD-11: 2A83] |
| P10415 | BCL2_HUMAN | Myeloproliferative neoplasm [ICD-11: 2A20] |
| P10415 | BCL2_HUMAN | Ovarian dysfunction [ICD-11: 5A80] |
| P10415 | BCL2_HUMAN | Prostate cancer [ICD-11: 2C82] |
| P10415 | BCL2_HUMAN | Lung cancer [ICD-11: 2C25] |
| P10415 | BCL2_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| P10415 | BCL2_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P10415 | BCL2_HUMAN | Chronic myelomonocytic leukaemia [ICD-11: 2A40] |
| P10415 | BCL2_HUMAN | Follicular lymphoma [ICD-11: 2A80] |
| P10415 | BCL2_HUMAN | Mature B-cell lymphoma [ICD-11: 2A85] |
| P10415 | BCL2_HUMAN | Myelodysplastic syndrome [ICD-11: 2A37] |
| P10415 | BCL2_HUMAN | Psoriasis [ICD-11: EA90] |
| P10415 | BCL2_HUMAN | Diffuse large B-cell lymphoma [ICD-11: 2A81] |
| P10415 | BCL2_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P10415 | BCL2_HUMAN | Leukaemia [ICD-11: 2A60-2B33] |
| P10415 | BCL2_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| P10415 | BCL2_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P10415 | BCL2_HUMAN | Colorectal cancer [ICD-11: 2B91] |
| P10415 | BCL2_HUMAN | Lung cancer [ICD-11: 2C25] |
| P10415 | BCL2_HUMAN | Lymphoma [ICD-11: 2A80-2A86] |
| P10415 | BCL2_HUMAN | Melanoma [ICD-11: 2C30] |
| P10415 | BCL2_HUMAN | Multiple myeloma [ICD-11: 2A83] |
| Q9HC29 | NOD2_HUMAN | Diabetes mellitus [ICD-11: 5A10] |
| Q9HC29 | NOD2_HUMAN | Hepatitis virus infection [ICD-11: 1E50-1E51] |
| Q9HC29 | NOD2_HUMAN | Sepsis [ICD-11: 1G40-1G41] |
| P00519 | ABL1_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| P00519 | ABL1_HUMAN | Heart beat abnormality [ICD-11: MC81] |
| P00519 | ABL1_HUMAN | Heart disease [ICD-11: BA41-BA42] |
| P00519 | ABL1_HUMAN | Ischemia [ICD-11: 8B10-8B11] |
| P00519 | ABL1_HUMAN | Mature B-cell lymphoma [ICD-11: 2A85] |
| P00519 | ABL1_HUMAN | Nutritional deficiency [ICD-11: 5B50-5B71] |
| P00519 | ABL1_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| P00519 | ABL1_HUMAN | Myeloproliferative neoplasm [ICD-11: 2A20] |
| P00519 | ABL1_HUMAN | Osteosarcoma [ICD-11: 2B51] |
| P00519 | ABL1_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P00519 | ABL1_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P00519 | ABL1_HUMAN | Cardiovascular disease [ICD-11: BA00-BE2Z] |
| P00519 | ABL1_HUMAN | Postoperative inflammation [ICD-11: 1A00-CA43] |
| P00519 | ABL1_HUMAN | Leukaemia [ICD-11: 2A60-2B33] |
| P00519 | ABL1_HUMAN | Myeloproliferative neoplasm [ICD-11: 2A20] |
| P11362 | FGFR1_HUMAN | Bladder cancer [ICD-11: 2C94] |
| P11362 | FGFR1_HUMAN | Colorectal cancer [ICD-11: 2B91] |
| P11362 | FGFR1_HUMAN | Idiopathic interstitial pneumonitis [ICD-11: CB03] |
| P11362 | FGFR1_HUMAN | Liver cancer [ICD-11: 2C12] |
| P11362 | FGFR1_HUMAN | Lung cancer [ICD-11: 2C25] |
| P11362 | FGFR1_HUMAN | Multiple myeloma [ICD-11: 2A83] |
| P11362 | FGFR1_HUMAN | Myelodysplastic syndrome [ICD-11: 2A37] |
| P11362 | FGFR1_HUMAN | Myeloproliferative neoplasm [ICD-11: 2A20] |
| P11362 | FGFR1_HUMAN | Ovarian cancer [ICD-11: 2C73] |
| P11362 | FGFR1_HUMAN | Peritoneal cancer [ICD-11: 2C51] |
| P11362 | FGFR1_HUMAN | Thrombocytopenia [ICD-11: 3B64] |
| P11362 | FGFR1_HUMAN | Acute diabete complication [ICD-11: 5A2Y] |
| P11362 | FGFR1_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P11362 | FGFR1_HUMAN | Stomach cancer [ICD-11: 2B72] |
| P11362 | FGFR1_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| P11362 | FGFR1_HUMAN | Coronary atherosclerosis [ICD-11: BA80] |
| P11362 | FGFR1_HUMAN | Endometrial cancer [ICD-11: 2C76] |
| P11362 | FGFR1_HUMAN | Epidermal dysplasias [ICD-11: EK90] |
| P11362 | FGFR1_HUMAN | Oesophagitis [ICD-11: DA24] |
| P11362 | FGFR1_HUMAN | Alzheimer disease [ICD-11: 8A20] |
| P11362 | FGFR1_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P11362 | FGFR1_HUMAN | Type 2 diabetes mellitus [ICD-11: 5A11] |
| P11362 | FGFR1_HUMAN | Retina cancer [ICD-11: 2D02] |
| P11362 | FGFR1_HUMAN | Chronic arterial occlusive disease [ICD-11: BD4Z] |
| P11362 | FGFR1_HUMAN | Gram-positive bacterial infection [ICD-11: 1B74-1F40] |
| Q12866 | MERTK_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| Q12866 | MERTK_HUMAN | Alzheimer disease [ICD-11: 8A20] |
| Q12866 | MERTK_HUMAN | Myelodysplastic syndrome [ICD-11: 2A37] |
| Q12866 | MERTK_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| Q12866 | MERTK_HUMAN | Brain cancer [ICD-11: 2A00] |
| Q12866 | MERTK_HUMAN | Mature B-cell lymphoma [ICD-11: 2A85] |