Basic Information

Terpenoid ID TKC055602
Cell line 0
Protein target 3
DiseaseNCIT 0
ORDO 0
ICD 14

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC055602 H9 HT clone H9; HT(H9); H 9; H-9 90000.0 nM IC50 C3366 Orphanet_3162
TKC055602 A2780 A-2780; 2780; A2780S; A2780par 30000.0 nM EC50 C7979 Orphanet_454723
TKC055602 8505C 8505c 1570.0 nM EC50 C3878 Orphanet_142
TKC055602 MCF7 1550.0 nM EC50 C4194
TKC055602 A549 1540.0 nM EC50 C3512
TKC055602 HT-29 HT 29; HT29 1690.0 nM EC50 C4349
TKC055602 NIH3T3 NIH/3T3; NIH-3T3; NIH3T3; 3T3; 3T3NIH; 3T3-Swiss; Swiss-3T3; Swiss/3T3; Swiss 3T3; Swiss3T3 35400.0 nM EC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC055602 O42275 Acetylcholinesterase ache 31640 nM Ki
TKC055602 P05771 Protein kinase C beta type PRKCB >150000 nM IC50
TKC055602 Q02156 Protein kinase C epsilon type PRKCE >150000 nM IC50
TKC055602 Q96RI1 Bile acid receptor NR1H4 0 nM EC50
TKC055602 Q8TDU6 G-protein coupled bile acid receptor 1 GPBAR1 3110 nM EC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P05771 KPCB_HUMAN Brain cancer [ICD-11: 2A00]
P05771 KPCB_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P05771 KPCB_HUMAN Diffuse large B-cell lymphoma [ICD-11: 2A81]
P05771 KPCB_HUMAN Lymphoma [ICD-11: 2A80-2A86]
P05771 KPCB_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P05771 KPCB_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P05771 KPCB_HUMAN Transplant rejection [ICD-11: NE84]
P05771 KPCB_HUMAN Mature B-cell leukaemia [ICD-11: 2A82]
P05771 KPCB_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P05771 KPCB_HUMAN Human immunodeficiency virus disease [ICD-11: 1C60-1C62]
Q02156 KPCE_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
Q02156 KPCE_HUMAN Liver vascular disorder [ICD-11: DB98]
Q02156 KPCE_HUMAN Malaria [ICD-11: 1F40-1F45]
Q02156 KPCE_HUMAN Alzheimer disease [ICD-11: 8A20]
Q02156 KPCE_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q02156 KPCE_HUMAN Human immunodeficiency virus disease [ICD-11: 1C60-1C62]
Q96RI1 NR1H4_HUMAN Autoimmune liver disease [ICD-11: DB96]
Q96RI1 NR1H4_HUMAN Cholelithiasis [ICD-11: DC11]
Q96RI1 NR1H4_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
Q96RI1 NR1H4_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
Q96RI1 NR1H4_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96RI1 NR1H4_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q96RI1 NR1H4_HUMAN Chronic kidney disease [ICD-11: GB61]
Q96RI1 NR1H4_HUMAN Skeletal anomaly [ICD-11: LD24]
Q96RI1 NR1H4_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
Q96RI1 NR1H4_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
Q96RI1 NR1H4_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
Q8TDU6 GPBAR_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
Q8TDU6 GPBAR_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
Q8TDU6 GPBAR_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]