Basic Information
| Terpenoid ID | TKC022945 |
|
| Chirality | TKC101617 | |
| Cell line | 0 | |
| Protein target | 39 | |
| DiseaseNCIT | 0 | |
| ORDO | 0 | |
| ICD | 129 |
| Terpenoid ID | TKC022945 |
|
| Chirality | TKC101617 | |
| Cell line | 0 | |
| Protein target | 39 | |
| DiseaseNCIT | 0 | |
| ORDO | 0 | |
| ICD | 129 |
| ID | Cell Line | Synonyms | Value | Unit | Type | NCIt | ORDO |
|---|---|---|---|---|---|---|---|
| TKC022945 | HepG2 | 1122.0 | nM | Potency | C3728 | Orphanet_449 | |
| TKC022945 | A2780 | A-2780; 2780; A2780S; A2780par | 4400.0 | nM | GI50 | C7979 | Orphanet_454723 |
| TKC022945 | ADDP cell line | A2780 ADDP; ADDP | 11000.0 | nM | IC50 | C7979 | Orphanet_454723 |
| TKC022945 | 143B | 143b; 143 B; 143B TK-; 143B.TK-; 143BTK-; 143TK-; HOS-143B; HOS-143b; GM05887; GM05887A | 10000.0 | nM | IC50 | C9145 | Orphanet_668 |
| TKC022945 | HCT-116 | HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 | 1977.0 | nM | GI50 | C4910 | |
| TKC022945 | HT-29 | HT 29; HT29 | 1656.0 | nM | GI50 | C4349 | |
| TKC022945 | G-401 | G401; G 401 | 3500.0 | nM | GI50 | C8715 | Orphanet_69077 |
| TKC022945 | NCI-H460 | NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 | 2723.0 | nM | GI50 | C4450 | |
| TKC022945 | L1210 | L 1210; L-1210; Leukemic 1210; Leukemia 1210; Leukemia L1210 | 15000.0 | nM | GI50 | C21604 | |
| TKC022945 | SW480 | SW-480; SW 480; SW480E | 4500.0 | nM | GI50 | C4349 | |
| TKC022945 | MCF7 | 7000.0 | nM | GI50 | C4194 | ||
| TKC022945 | A-431 | A431; A431/P | 2900.0 | nM | GI50 | C4819 | |
| TKC022945 | DU-145 | DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 | 1021.0 | nM | GI50 | C4863 | |
| TKC022945 | H4 | H-4 | 24.0 | % | Activity | C60781 | Orphanet_94 |
| TKC022945 | HepG2 | 11000.0 | nM | IC50 | C3728 | Orphanet_449 | |
| TKC022945 | SK-HEP1 | SK-Hep-1; SK HEP-1; SK HEP 01; SK-Hep1; Sk-Hep1; SK Hep1; SKHEP-1; SKHEP1; SKHep1; SK_HEP1 | 34000.0 | nM | IC50 | C7106 | |
| TKC022945 | Hepatocyte | 21000.0 | nM | IC50 | |||
| TKC022945 | MDA-N | MDAN | 2911.0 | nM | GI50 | C3802 | |
| TKC022945 | SN12C | SN-12C | 2009.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC022945 | ACHN | 1183.0 | nM | GI50 | C6975 | Orphanet_319298 | |
| TKC022945 | NCI-H23 | NCI.H23; NCI H23; H-23; H23; NCIH23 | 5070.0 | nM | GI50 | C3512 | |
| TKC022945 | HOP-92 | HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 | 610.0 | nM | GI50 | C2926 | |
| TKC022945 | UO-31 | UO.31; UO31; U031 | 2636.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC022945 | HL-60 | HL 60; HL.60 HL60; Human Leukemia-60 | 1633.0 | nM | GI50 | C9154 | Orphanet_519 |
| TKC022945 | SK-MEL-5 | SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel | 973.0 | nM | GI50 | C3510 | |
| TKC022945 | SF-539 | SF-539; SF-539 BT; SF.539; SF 539 | 2042.0 | nM | GI50 | C3796 | Orphanet_251576 |
| TKC022945 | K562 | K562; K.562; K 562; KO; GM05372; GM05372E | 2301.0 | nM | GI50 | C9110 | Orphanet_521 |
| TKC022945 | Malme-3M | MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer | 1337.0 | nM | GI50 | C3224 | |
| TKC022945 | A498 | A498 | 1125.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC022945 | MOLT-4 | Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D | 9795.0 | nM | GI50 | C9142 | Orphanet_99861 |
| TKC022945 | OVCAR-3 | Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 | 759.0 | nM | GI50 | C105555 | |
| TKC022945 | NCI/ADR-RES | NCI/ADR-RES; NCI.ADR.RES; NCIADR.RES; NCI/ADRRES; NCIADRRES; ADR-RES; MCF-7/ADR; MCF-7/ADR-RES; MCF-7/AdrR; MCF-7/Adr; MCF-7/adr; MCF-7ADR; MCF7-ADR; MCF7ADR; OVCAR-8/ADR; OVCAR8/ADR | 6501.0 | nM | GI50 | C105555 | |
| TKC022945 | HOP-62 | HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 | 2443.0 | nM | GI50 | C3512 | |
| TKC022945 | OVCAR-8 | OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 | 5984.0 | nM | GI50 | C105555 | |
| TKC022945 | U-251 | U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) | 1413.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC022945 | SNB-19 | SNB.19; SNB19; Surgical Neurology Branch-19 | 1099.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC022945 | OVCAR-5 | OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 | 2455.0 | nM | GI50 | C105555 | |
| TKC022945 | MDA-MB-231 | MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 | 1330.0 | nM | GI50 | C5214 | |
| TKC022945 | TK-10 | TK.10; TK 10; TK10 | 313.0 | nM | GI50 | C4033 | Orphanet_319276 |
| TKC022945 | SR | SR-786; SR786 | 2606.0 | nM | GI50 | C37193 | Orphanet_300895 |
| TKC022945 | SW-620 | SW-620; SW 620; SW.620 | 3837.0 | nM | GI50 | C4349 | |
| TKC022945 | KM12 | KM-12; KM.12 | 5420.0 | nM | GI50 | C4910 | |
| TKC022945 | NCI-H522 | NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 | 935.0 | nM | GI50 | C3512 | |
| TKC022945 | M14 | M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 | 1702.0 | nM | GI50 | C3802 | |
| TKC022945 | NCI-H322M | NCI.H322M; H322M; H-322M; H-322m | 2018.0 | nM | GI50 | C2923 | |
| TKC022945 | RPMI-8226 | RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson | 2084.0 | nM | GI50 | C3242 | Orphanet_29073 |
| TKC022945 | OVCAR-4 | OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 | 2582.0 | nM | GI50 | C105555 | |
| TKC022945 | LOX IMVI | LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX | 2234.0 | nM | GI50 | C3802 | |
| TKC022945 | BT-549 | BT 549; BT.549; BT549 | 1698.0 | nM | GI50 | C4194 | |
| TKC022945 | SK-MEL-2 | SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 | 1452.0 | nM | GI50 | C3224 | |
| TKC022945 | HCC 2998 | HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 | 1531.0 | nM | GI50 | C4349 | |
| TKC022945 | A549 | 918.0 | nM | GI50 | C3512 | ||
| TKC022945 | SNB-75 | SNB.75; SNB75; Surgical Neurology Branch-75 | 472.0 | nM | GI50 | C3058 | Orphanet_360 |
| TKC022945 | HCT-15 | HCT-15; HCT.15; HCT15 | 4055.0 | nM | GI50 | C4349 | |
| TKC022945 | EKVX | 450.0 | nM | GI50 | C3512 | ||
| TKC022945 | SF-268 | SF-268; SF.268; SF 268 | 1766.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC022945 | PC-3 | PC3; PC.3 | 279.0 | nM | GI50 | C4863 | |
| TKC022945 | SK-OV-3 | SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 | 2168.0 | nM | GI50 | C7978 | |
| TKC022945 | T47D | 1683.0 | nM | GI50 | C4194 | ||
| TKC022945 | UACC-62 | UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 | 2118.0 | nM | GI50 | C3224 | |
| TKC022945 | CAKI-1 | CAL 1; Centre Antoine Lacassagne-1 | 791.0 | nM | GI50 | C3224 | |
| TKC022945 | SF-295 | SF-295; SF.295; SF 295 | 1368.0 | nM | GI50 | C3058 | Orphanet_360 |
| TKC022945 | MDA-MB-435 | MDA-MB435; MDAMB435; MDA.MB.435; MDA-435; MDA 435; MDA435; MD Anderson-Metastatic Breast-435 | 1892.0 | nM | GI50 | C3802 | |
| TKC022945 | IGROV-1 | Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P | 2158.0 | nM | GI50 | C7979 | Orphanet_454723 |
| TKC022945 | Hs-578T | HS 578T; Hs-578T; HS-578T; Hs_578t; Hs-578-T; HS-578-T; Hs 578.T; HS578T; Hs578T; Hs578t; HS0578T; 578T; HS578; Hs578; Homo sapiens No. 578, tumor cells | 1033.0 | nM | GI50 | C4194 | |
| TKC022945 | 786-0 | 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT | 1738.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC022945 | UACC-257 | UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 | 2655.0 | nM | GI50 | C3224 | |
| TKC022945 | CCRF-CEM | CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C | 1194.0 | nM | GI50 | C7953 | Orphanet_99861 |
| TKC022945 | NCI-H226 | NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 | 1062.0 | nM | GI50 | C45662 | Orphanet_50251 |
| TKC022945 | RXF 393 | RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL | 484.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC022945 | SK-MEL-28 | SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 | 3483.0 | nM | GI50 | C3510 | |
| TKC022945 | COLO 205 | Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 | 427.0 | nM | GI50 | C4349 | |
| TKC022945 | HEK293 | 2908.0 | nM | Potency | |||
| TKC022945 | SH-SY5Y | SH-Sy5y; SHSY5Y; SHSY-5Y; SK-SH-SY5Y; SY5Y; SH-SY5Y Parental | 3548.0 | nM | Potency | C3270 | Orphanet_635 |
| ID | Uniport | Pref_name | Gene name | value | unit | type |
|---|---|---|---|---|---|---|
| TKC022945 | Q16637 | Survival motor neuron protein | SMN1,SMN2 | 10000 | nM | Potency |
| TKC022945 | Q16637 | Survival motor neuron protein | SMN1,SMN2 | 10000 | nM | Potency |
| TKC022945 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | PTPN1 | 3600 | nM | IC50 |
| TKC022945 | Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | SLCO1B3 | 106 | % | Inhibition |
| TKC022945 | Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | SLCO1B1 | 102 | % | Inhibition |
| TKC022945 | O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | IDH1 | 1458 | nM | Potency |
| TKC022945 | P43220 | Glucagon-like peptide 1 receptor | GLP1R | 1778 | nM | Potency |
| TKC022945 | P84022 | Mothers against decapentaplegic homolog 3 | SMAD3 | 1585 | nM | Potency |
| TKC022945 | Q03431 | Parathyroid hormone/parathyroid hormone-related peptide receptor | PTH1R | 4467 | nM | Potency |
| TKC022945 | Q16236 | Nuclear factor erythroid 2-related factor 2 | NFE2L2 | 7308 | nM | Potency |
| TKC022945 | Q99700 | Ataxin-2 | ATXN2 | 3162 | nM | Potency |
| TKC022945 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | APEX1 | 50 | nM | Potency |
| TKC022945 | O75496 | Geminin | GMNN | 6513 | nM | Potency |
| TKC022945 | P37840 | Alpha-synuclein | SNCA | 5623 | nM | Potency |
| TKC022945 | P39748 | Flap endonuclease 1 | FEN1 | 37686 | nM | Potency |
| TKC022945 | O42275 | Acetylcholinesterase | ache | -8 | % | Inhibition |
| TKC022945 | P0DTD1 | Replicase polyprotein 1ab | rep | 0 | % | Inhibition |
| TKC022945 | P28482 | Mitogen-activated protein kinase 1 | MAPK1 | 5012 | nM | Potency |
| TKC022945 | P81908 | Cholinesterase | BCHE | -2 | % | Inhibition |
| TKC022945 | P00811 | Beta-lactamase | ampC | 6310 | nM | Potency |
| TKC022945 | Q96QE3 | ATPase family AAA domain-containing protein 5 | ATAD5 | 2592 | nM | Potency |
| TKC022945 | P54132 | Bloom syndrome protein | BLM | 45 | nM | Potency |
| TKC022945 | Q01453 | Peripheral myelin protein 22 | PMP22 | 21331 | nM | Potency |
| TKC022945 | B2RXH2 | Lysine-specific demethylase 4E | KDM4E | 39811 | nM | Potency |
| TKC022945 | Q92830 | Histone acetyltransferase KAT2A | KAT2A | 15849 | nM | Potency |
| TKC022945 | Q16665 | Hypoxia-inducible factor 1-alpha | HIF1A | 2512 | nM | Potency |
| TKC022945 | P51450 | Nuclear receptor ROR-gamma | Rorc | 5012 | nM | Potency |
| TKC022945 | P02545 | Prelamin-A/C | LMNA | 1122 | nM | Potency |
| TKC022945 | O15118 | NPC intracellular cholesterol transporter 1 | NPC1 | 316 | nM | Potency |
| TKC022945 | P51151 | Ras-related protein Rab-9A | RAB9A | 562 | nM | Potency |
| TKC022945 | P42345 | Serine/threonine-protein kinase mTOR | MTOR | 4645 | nM | Potency |
| TKC022945 | P04637 | Cellular tumor antigen p53 | TP53 | 10000 | nM | Potency |
| TKC022945 | Q194T2 | Non-structural protein 1 | NS1 | 5623 | nM | Potency |
| TKC022945 | P15289 | Arylsulfatase A | ARSA | 849 | nM | Potency |
| TKC022945 | P25094 | Peripheral myelin protein 22 | Pmp22 | 616 | nM | Potency |
| TKC022945 | P62136 | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | PPP1CA | 272 | nM | IC50 |
| TKC022945 | Q9BPW0 | Serine/threonine-protein phosphatase | PPP5C | 239 | nM | IC50 |
| TKC022945 | O75688 | Protein phosphatase 1B | PPM1B | 430 | nM | IC50 |
| TKC022945 | O75688 | Protein phosphatase 1B | PPM1B | 1780 | nM | IC50 |
| TKC022945 | P36873 | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | PPP1CC | 1780 | nM | IC50 |
| TKC022945 | Q8AWE3 | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B | 200 | nM | IC50 | |
| TKC022945 | O15648 | ATP-dependent 6-phosphofructokinase | pfk | 757 | nM | Potency |
| TKC022945 | P05067 | Amyloid-beta precursor protein | APP | 23109 | nM | Potency |
| TKC022945 | P97697 | Inositol monophosphatase 1 | Impa1 | 10000 | nM | Potency |
| TKC022945 | Q76MZ3 | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | Ppp2r1a | 8000 | nM | IC50 |
| TKC022945 | O43521 | Bcl-2-like protein 11 | BCL2L11 | >350000 | nM | EC50 |
| TKC022945 | P03206 | Trans-activator protein BZLF1 | BZLF1 | 239.16 | nM | IC50 |
| Uniport ID | Uniport Name | ICD-11 |
|---|---|---|
| Q16637 | SMN_HUMAN | Muscular atrophy [ICD-11: 8B61] |
| Q16637 | SMN_HUMAN | Muscular atrophy [ICD-11: 8B61] |
| Q16637 | SMN_HUMAN | Muscular atrophy [ICD-11: 8B61] |
| Q16637 | SMN_HUMAN | Muscular atrophy [ICD-11: 8B61] |
| P18031 | PTN1_HUMAN | Type 2 diabetes mellitus [ICD-11: 5A11] |
| P18031 | PTN1_HUMAN | Acute diabete complication [ICD-11: 5A2Y] |
| P18031 | PTN1_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| P18031 | PTN1_HUMAN | Obesity [ICD-11: 5B80-5B81] |
| P18031 | PTN1_HUMAN | Ophthalmic devices/implants/grafts injury [ICD-11: PK97] |
| P18031 | PTN1_HUMAN | Postoperative inflammation [ICD-11: 1A00-CA43] |
| P18031 | PTN1_HUMAN | Metabolic disorder [ICD-11: 5C50-5D2Z] |
| P18031 | PTN1_HUMAN | Type 2 diabetes mellitus [ICD-11: 5A11] |
| O75874 | IDHC_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| O75874 | IDHC_HUMAN | Liver cancer [ICD-11: 2C12] |
| O75874 | IDHC_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| O75874 | IDHC_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| O75874 | IDHC_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| O75874 | IDHC_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P43220 | GLP1R_HUMAN | Cardiovascular disease [ICD-11: BA00-BE2Z] |
| P43220 | GLP1R_HUMAN | Obesity [ICD-11: 5B80-5B81] |
| P43220 | GLP1R_HUMAN | Type 2 diabetes mellitus [ICD-11: 5A11] |
| P43220 | GLP1R_HUMAN | Type-1/2 diabete [ICD-11: 5A10-5A11] |
| P43220 | GLP1R_HUMAN | Acute diabete complication [ICD-11: 5A2Y] |
| P43220 | GLP1R_HUMAN | Diabetes mellitus [ICD-11: 5A10] |
| P43220 | GLP1R_HUMAN | Dyspepsia [ICD-11: MD92] |
| P43220 | GLP1R_HUMAN | Irritable bowel syndrome [ICD-11: DD91] |
| P43220 | GLP1R_HUMAN | Intracranial injury [ICD-11: NA07] |
| P43220 | GLP1R_HUMAN | Non-alcoholic fatty liver disease [ICD-11: DB92] |
| P84022 | SMAD3_HUMAN | Herpes simplex infection [ICD-11: 1F00] |
| P84022 | SMAD3_HUMAN | Kidney fibrosis [ICD-11: GC01] |
| Q03431 | PTH1R_HUMAN | Low bone mass disorder [ICD-11: FB83] |
| Q03431 | PTH1R_HUMAN | Hypo-parathyroidism [ICD-11: 5A50] |
| Q16236 | NF2L2_HUMAN | Ataxic disorder [ICD-11: 8A03] |
| Q16236 | NF2L2_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| Q16236 | NF2L2_HUMAN | Glaucoma [ICD-11: 9C61] |
| Q16236 | NF2L2_HUMAN | Lung cancer [ICD-11: 2C25] |
| Q16236 | NF2L2_HUMAN | Macular degeneration [ICD-11: 9B75] |
| Q16236 | NF2L2_HUMAN | Melanoma [ICD-11: 2C30] |
| Q16236 | NF2L2_HUMAN | Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z] |
| Q16236 | NF2L2_HUMAN | Pulmonary hypertension [ICD-11: BB01] |
| Q16236 | NF2L2_HUMAN | Subarachnoid haemorrhage [ICD-11: 8B01] |
| Q16236 | NF2L2_HUMAN | Urinary system clinical sympton [ICD-11: MF8Y] |
| Q16236 | NF2L2_HUMAN | Non-alcoholic fatty liver disease [ICD-11: DB92] |
| Q16236 | NF2L2_HUMAN | Alpha-1-antitrypsin deficiency [ICD-11: 5C5A] |
| Q16236 | NF2L2_HUMAN | Motor neuron disease [ICD-11: 8B60] |
| Q16236 | NF2L2_HUMAN | Multiple sclerosis [ICD-11: 8A40] |
| P27695 | APEX1_HUMAN | Retinopathy [ICD-11: 9B71] |
| P27695 | APEX1_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P27695 | APEX1_HUMAN | Ocular cancer [ICD-11: 2D00-2D07] |
| P27695 | APEX1_HUMAN | Brain cancer [ICD-11: 2A00] |
| P27695 | APEX1_HUMAN | Melanoma [ICD-11: 2C30] |
| P37840 | SYUA_HUMAN | Parkinsonism [ICD-11: 8A00] |
| P37840 | SYUA_HUMAN | Alzheimer disease [ICD-11: 8A20] |
| P37840 | SYUA_HUMAN | Autonomic nervous system disorder [ICD-11: 8D87] |
| P28482 | MK01_HUMAN | Melanoma [ICD-11: 2C30] |
| P28482 | MK01_HUMAN | Pancreatic cancer [ICD-11: 2C10] |
| P28482 | MK01_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P28482 | MK01_HUMAN | Arteries/arterioles disorder [ICD-11: BD52] |
| P28482 | MK01_HUMAN | Allergic/hypersensitivity disorder [ICD-11: 4A80-4A8Z] |
| P28482 | MK01_HUMAN | Transplant rejection [ICD-11: NE84] |
| P28482 | MK01_HUMAN | Mature T-cell lymphoma [ICD-11: 2A90] |
| P28482 | MK01_HUMAN | Rheumatoid arthritis [ICD-11: FA20] |
| Q16665 | HIF1A_HUMAN | Adrenomedullary hyperfunction [ICD-11: 5A75] |
| Q16665 | HIF1A_HUMAN | Brain cancer [ICD-11: 2A00] |
| Q16665 | HIF1A_HUMAN | Lymphoma [ICD-11: 2A80-2A86] |
| Q16665 | HIF1A_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| Q16665 | HIF1A_HUMAN | Pulmonary hypertension [ICD-11: BB01] |
| P51151 | RAB9A_HUMAN | Fungal infection [ICD-11: 1F29-1F2F] |
| P42345 | MTOR_HUMAN | Arteries/arterioles disorder [ICD-11: BD52] |
| P42345 | MTOR_HUMAN | Chronic myelomonocytic leukaemia [ICD-11: 2A40] |
| P42345 | MTOR_HUMAN | Hydrocephalus [ICD-11: 8D64] |
| P42345 | MTOR_HUMAN | Multiple myeloma [ICD-11: 2A83] |
| P42345 | MTOR_HUMAN | Renal cell carcinoma [ICD-11: 2C90] |
| P42345 | MTOR_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P42345 | MTOR_HUMAN | Transplant rejection [ICD-11: NE84] |
| P42345 | MTOR_HUMAN | Sarcoma [ICD-11: 2A60-2C35] |
| P42345 | MTOR_HUMAN | Bladder cancer [ICD-11: 2C94] |
| P42345 | MTOR_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| P42345 | MTOR_HUMAN | Endometrial cancer [ICD-11: 2C76] |
| P42345 | MTOR_HUMAN | Head and neck cancer [ICD-11: 2D42] |
| P42345 | MTOR_HUMAN | Liver cancer [ICD-11: 2C12] |
| P42345 | MTOR_HUMAN | Lung cancer [ICD-11: 2C25] |
| P42345 | MTOR_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| P42345 | MTOR_HUMAN | Malignant mesenchymal neoplasm [ICD-11: 2B5D-2B5Y] |
| P42345 | MTOR_HUMAN | Metastatic lymph node neoplasm [ICD-11: 2D60] |
| P42345 | MTOR_HUMAN | Pain [ICD-11: MG30-MG3Z] |
| P42345 | MTOR_HUMAN | Pancreatic cancer [ICD-11: 2C10] |
| P42345 | MTOR_HUMAN | Prostate cancer [ICD-11: 2C82] |
| P42345 | MTOR_HUMAN | Pulmonary hypertension [ICD-11: BB01] |
| P42345 | MTOR_HUMAN | Lymphangioleiomyomatosis [ICD-11: CB07] |
| P42345 | MTOR_HUMAN | Lymphoma [ICD-11: 2A80-2A86] |
| P42345 | MTOR_HUMAN | Pleural mesothelioma [ICD-11: 2C26] |
| P42345 | MTOR_HUMAN | Mature T-cell lymphoma [ICD-11: 2A90] |
| P42345 | MTOR_HUMAN | Postoperative inflammation [ICD-11: 1A00-CA43] |
| P42345 | MTOR_HUMAN | Ulcerative colitis [ICD-11: DD71] |
| P04637 | P53_HUMAN | Arterial occlusive disease [ICD-11: BD40] |
| P04637 | P53_HUMAN | Lip/oral cavity/pharynx neoplasm [ICD-11: 2B6E] |
| P04637 | P53_HUMAN | Metastatic liver/bile duct neoplasm [ICD-11: 2D80] |
| P04637 | P53_HUMAN | Transplant rejection [ICD-11: NE84] |
| P04637 | P53_HUMAN | Ovarian dysfunction [ICD-11: 5A80] |
| P04637 | P53_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P04637 | P53_HUMAN | Bladder cancer [ICD-11: 2C94] |
| P04637 | P53_HUMAN | Brain cancer [ICD-11: 2A00] |
| P04637 | P53_HUMAN | Colorectal cancer [ICD-11: 2B91] |
| P04637 | P53_HUMAN | Esophageal cancer [ICD-11: 2B70] |
| P04637 | P53_HUMAN | Head and neck cancer [ICD-11: 2D42] |
| P04637 | P53_HUMAN | Mature B-cell leukaemia [ICD-11: 2A82] |
| P04637 | P53_HUMAN | Myelodysplastic syndrome [ICD-11: 2A37] |
| P04637 | P53_HUMAN | Ovarian cancer [ICD-11: 2C73] |
| P04637 | P53_HUMAN | Pancreatic cancer [ICD-11: 2C10] |
| P04637 | P53_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P04637 | P53_HUMAN | Stomach cancer [ICD-11: 2B72] |
| P04637 | P53_HUMAN | Cervical cancer [ICD-11: 2C77] |
| P04637 | P53_HUMAN | Endometrial cancer [ICD-11: 2C76] |
| P04637 | P53_HUMAN | Fallopian tube cancer [ICD-11: 2C74] |
| P04637 | P53_HUMAN | Liposarcoma [ICD-11: 2B59] |
| P04637 | P53_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| P04637 | P53_HUMAN | Peritoneal cancer [ICD-11: 2C51] |
| P04637 | P53_HUMAN | Toxicity [ICD-11: N.A.] |
| P04637 | P53_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P04637 | P53_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P04637 | P53_HUMAN | Kidney failure [ICD-11: GB60-GB6Z] |
| P04637 | P53_HUMAN | Hearing disorder [ICD-11: AB50-AB57] |
| P15289 | ARSA_HUMAN | Lysosomal disease [ICD-11: 5C56] |
| P62136 | PP1A_HUMAN | Molluscum contagiosum [ICD-11: 1E76] |
| P05067 | A4_HUMAN | Diagnostic imaging [ICD-11: N.A.] |
| P05067 | A4_HUMAN | Alzheimer disease [ICD-11: 8A20] |
| P05067 | A4_HUMAN | Desmoid tumour [ICD-11: 2F7C] |
| P05067 | A4_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P05067 | A4_HUMAN | Retinopathy [ICD-11: 9B71] |
| P05067 | A4_HUMAN | Dystrophic epidermolysis bullosa [ICD-11: EC32] |
| P05067 | A4_HUMAN | Amyloidosis [ICD-11: 5D00] |
| P05067 | A4_HUMAN | Macular degeneration [ICD-11: 9B75] |
| P05067 | A4_HUMAN | Intracranial injury [ICD-11: NA07] |
| P05067 | A4_HUMAN | Brain cancer [ICD-11: 2A00] |
| P05067 | A4_HUMAN | Dissociative neurological symptom disorder [ICD-11: 6B60] |
| P05067 | A4_HUMAN | Mild neurocognitive disorder [ICD-11: 6D71] |