Basic Information

Terpenoid ID TKC101617
Chirality TKC022945
Cell line 0
Protein target 7
DiseaseNCIT 0
ORDO 0
ICD 12

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC101617 P10636 Microtubule-associated protein tau MAPT 25119 nM Potency
TKC101617 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 22387 nM Potency
TKC101617 P08684 Cytochrome P450 3A4 CYP3A4 7943 nM AC50
TKC101617 P05177 Cytochrome P450 1A2 CYP1A2 31623 nM AC50
TKC101617 O00255 Menin MEN1 39811 nM Potency
TKC101617 Q9F4F7 4'-phosphopantetheinyl transferase ffp ffp 70795 nM Potency
TKC101617 P16473 Thyrotropin receptor TSHR 31623 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
P16473 TSHR_HUMAN Hypo-thyroidism [ICD-11: 5A00]
P16473 TSHR_HUMAN Thyroid cancer [ICD-11: 2D10]