Basic Information

Terpenoid ID TKC108267
Chirality TKC139366
Cell line 3
Protein target 1
DiseaseNCIT 3
ORDO 0
ICD 27

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC108267 MCF7 16.0 % Inhibition C4194
TKC108267 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 3.0 % Inhibition C4863
TKC108267 SW-620 SW-620; SW 620; SW.620 1.0 % Inhibition C4349
TKC108267 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 49.0 % GI C4349
TKC108267 HEp-2 Hep-2; HEP-2; Hep2 (HeLa derivative); HEp-2/HeLa; Hep 2; Hep2; HEp2; HEP2; H.Ep.-2; H.Ep. #2; H.Ep. No. 2; Hep II; Human Epidermoid carcinoma #2; Human Epithelioma-2 51.0 % GI C27677
TKC108267 PC-3 PC3; PC.3 70.0 % GI C4863
TKC108267 HUVEC HUV-EC-C; HUVEC 27230.0 nM IC50
TKC108267 PBMC 50.0 % Inhibition

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC108267 P35968 Vascular endothelial growth factor receptor 2 KDR 0 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P35968 VGFR2_HUMAN Degenerative high myopia [ICD-11: 9B76]
P35968 VGFR2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P35968 VGFR2_HUMAN Colorectal cancer [ICD-11: 2B91]
P35968 VGFR2_HUMAN Gastrointestinal stromal tumour [ICD-11: 2B5B]
P35968 VGFR2_HUMAN Liver cancer [ICD-11: 2C12]
P35968 VGFR2_HUMAN Lung cancer [ICD-11: 2C25]
P35968 VGFR2_HUMAN Malignant digestive organ neoplasm [ICD-11: 2C11]
P35968 VGFR2_HUMAN Melanoma [ICD-11: 2C30]
P35968 VGFR2_HUMAN Multiple myeloma [ICD-11: 2A83]
P35968 VGFR2_HUMAN Myelodysplastic syndrome [ICD-11: 2A37]
P35968 VGFR2_HUMAN Ovarian cancer [ICD-11: 2C73]
P35968 VGFR2_HUMAN Renal cell carcinoma [ICD-11: 2C90]
P35968 VGFR2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P35968 VGFR2_HUMAN Stomach cancer [ICD-11: 2B72]
P35968 VGFR2_HUMAN Thrombocytopenia [ICD-11: 3B64]
P35968 VGFR2_HUMAN Thyroid cancer [ICD-11: 2D10]
P35968 VGFR2_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P35968 VGFR2_HUMAN Peritoneal cancer [ICD-11: 2C51]
P35968 VGFR2_HUMAN Sarcoma [ICD-11: 2A60-2C35]
P35968 VGFR2_HUMAN Brain cancer [ICD-11: 2A00]
P35968 VGFR2_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P35968 VGFR2_HUMAN Chronic pain [ICD-11: MG30]
P35968 VGFR2_HUMAN Metastatic lymph node neoplasm [ICD-11: 2D60]
P35968 VGFR2_HUMAN Non-small cell lung cancer [ICD-11: 2C25]
P35968 VGFR2_HUMAN Alzheimer disease [ICD-11: 8A20]
P35968 VGFR2_HUMAN Digestive organ benign neoplasm [ICD-11: 2E92]
P35968 VGFR2_HUMAN Head and neck cancer [ICD-11: 2D42]
P35968 VGFR2_HUMAN Circulatory system disease [ICD-11: BE2Z]