Basic Information

Terpenoid ID TKC046098
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 15

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC046098 A549 4.0 ug ml-1 ED50 C3512
TKC046098 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 7.0 ug ml-1 ED50 C7978
TKC046098 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 9.0 ug ml-1 ED50 C3224
TKC046098 XF498 XF-498; XF498 5.0 ug ml-1 ED50 C3058 Orphanet_360
TKC046098 HCT-15 HCT-15; HCT.15; HCT15 7.0 ug ml-1 ED50 C4349
TKC046098 L6 L-6; L-6 myoblast 150000.0 nM IC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC046098 P49841 Glycogen synthase kinase-3 beta GSK3B 794 nM IC50
TKC046098 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 USP7 2700 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P49841 GSK3B_HUMAN Myotonic disorder [ICD-11: 8C71]
P49841 GSK3B_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P49841 GSK3B_HUMAN Fragile X chromosome [ICD-11: LD55]
P49841 GSK3B_HUMAN Myeloproliferative neoplasm [ICD-11: 2A20]
P49841 GSK3B_HUMAN Osteosarcoma [ICD-11: 2B51]
P49841 GSK3B_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P49841 GSK3B_HUMAN Parkinsonism [ICD-11: 8A00]
P49841 GSK3B_HUMAN Allergic/hypersensitivity disorder [ICD-11: 4A80-4A8Z]
P49841 GSK3B_HUMAN Brain cancer [ICD-11: 2A00]
P49841 GSK3B_HUMAN Ovarian cancer [ICD-11: 2C73]
P49841 GSK3B_HUMAN Transplant rejection [ICD-11: NE84]
P49841 GSK3B_HUMAN Alzheimer disease [ICD-11: 8A20]
P49841 GSK3B_HUMAN Acute diabete complication [ICD-11: 5A2Y]
Q93009 UBP7_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q93009 UBP7_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]