Basic Information

Terpenoid ID TKC066332
Cell line 0
Protein target 9
DiseaseNCIT 0
ORDO 0
ICD 18

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC066332 P10636 Microtubule-associated protein tau MAPT 39811 nM Potency
TKC066332 Q16637 Survival motor neuron protein SMN1,SMN2 31623 nM Potency
TKC066332 Q16637 Survival motor neuron protein SMN1,SMN2 31623 nM Potency
TKC066332 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 1122 nM Potency
TKC066332 P08684 Cytochrome P450 3A4 CYP3A4 1259 nM Potency
TKC066332 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 31623 nM Potency
TKC066332 Q9UBT6 DNA polymerase kappa POLK 28184 nM Potency
TKC066332 O94782 Ubiquitin carboxyl-terminal hydrolase 1 USP1 44668 nM Potency
TKC066332 P51450 Nuclear receptor ROR-gamma Rorc 2818 nM Potency
TKC066332 O75604 Ubiquitin carboxyl-terminal hydrolase 2 USP2 10000 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]
O94782 UBP1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75604 UBP2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]