Basic Information

Terpenoid ID TKC113582
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 0

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC113582 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 3000.0 nM EC50 C7953 Orphanet_99861
TKC113582 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 3000.0 nM EC50 C7953 Orphanet_99861

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC113582 P25099 Adenosine receptor A1 Adora1 1 nM Kd
TKC113582 P11802 Cyclin-dependent kinase 4 CDK4 10 ug.mL-1 IC50
TKC113582 P50281 Matrix metalloproteinase-14 MMP14 19 ug.mL-1 IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P11802 CDK4_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P11802 CDK4_HUMAN Lung cancer [ICD-11: 2C25]
P11802 CDK4_HUMAN Psoriasis [ICD-11: EA90]
P11802 CDK4_HUMAN Schizophrenia [ICD-11: 6A20]
P11802 CDK4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11802 CDK4_HUMAN Mature B-cell lymphoma [ICD-11: 2A85]
P11802 CDK4_HUMAN Brain cancer [ICD-11: 2A00]
P11802 CDK4_HUMAN Liposarcoma [ICD-11: 2B59]
P11802 CDK4_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P11802 CDK4_HUMAN Prostate cancer [ICD-11: 2C82]
P11802 CDK4_HUMAN Retina cancer [ICD-11: 2D02]
P50281 MMP14_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
P50281 MMP14_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P50281 MMP14_HUMAN Corneal disease [ICD-11: 9A76-9A78]