Basic Information

Terpenoid ID TKC056469
Cell line 0
Protein target 7
DiseaseNCIT 0
ORDO 0
ICD 6

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC056469 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 10000.0 nM IC50 C27677
TKC056469 BGC-823 BGC823 19360.0 nM IC50 C27677
TKC056469 ASPC1 AsPc-1; Aspc-1; ASPC-1; As-PC1; ASPC1; AsPC1; Aspc1; AsPc1 71000.0 nM IC50 C9120
TKC056469 HT-29 HT 29; HT29 23890.0 nM IC50 C4349
TKC056469 HepG2 37670.0 nM IC50 C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC056469 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 19953 nM Potency
TKC056469 P11511 Aromatase CYP19A1 43 ug.mL-1 IC50
TKC056469 P46063 ATP-dependent DNA helicase Q1 RECQL 562 nM Potency
TKC056469 P06746 DNA polymerase beta POLB 39811 nM Potency
TKC056469 P10520 Streptokinase A ska 2828 nM EC50
TKC056469 P51450 Nuclear receptor ROR-gamma Rorc 355 nM Potency
TKC056469 Q194T2 Non-structural protein 1 NS1 3981 nM Potency
TKC056469 P00489 Glycogen phosphorylase, muscle form PYGM 131000 nM IC50
TKC056469 P05227 Histidine-rich protein PFHRP-II 0 % Inhibition
TKC056469 P09810 Tryptophan 5-hydroxylase 1 Tph1 1 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]
P11511 CP19A_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P11511 CP19A_HUMAN Cushing syndrome [ICD-11: 5A70]
P11511 CP19A_HUMAN Oesophagitis [ICD-11: DA24]
P11511 CP19A_HUMAN Endometriosis [ICD-11: GA10]
P11511 CP19A_HUMAN Neuropathy [ICD-11: 8C0Z]
P11511 CP19A_HUMAN Bladder cancer [ICD-11: 2C94]
P11511 CP19A_HUMAN Prostate disease [ICD-11: GA91]
P06746 DPOLB_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]