Basic Information

Terpenoid ID TKC026309
Cell line 0
Protein target 5
DiseaseNCIT 0
ORDO 0
ICD 37

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC026309 P388 P-388 1.0 ug.mL-1 IC50 C21602
TKC026309 HCT-8 HCT-8; HCT8 1.0 ug.mL-1 IC50 C4349
TKC026309 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 27000.0 nM IC50 C9154 Orphanet_519
TKC026309 KB KB (HeLa derivative); HeLa-KB; Strain KB 1.0 ug.mL-1 IC50 C27677
TKC026309 786-0 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT 17700.0 nM IC50 C9385 Orphanet_217071

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC026309 P11597 Cholesteryl ester transfer protein CETP 6000 nM IC50
TKC026309 P16050 Polyunsaturated fatty acid lipoxygenase ALOX15 ALOX15 760 nM IC50
TKC026309 P18054 Polyunsaturated fatty acid lipoxygenase ALOX12 ALOX12 2400 nM IC50
TKC026309 Q99814 Endothelial PAS domain-containing protein 1 EPAS1 3300 nM EC50
TKC026309 P09917 Polyunsaturated fatty acid 5-lipoxygenase ALOX5 680 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P11597 CETP_HUMAN Arterial occlusive disease [ICD-11: BD40]
P11597 CETP_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P11597 CETP_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P11597 CETP_HUMAN Myocardial infarction [ICD-11: BA41-BA43]
P11597 CETP_HUMAN Inborn lipid metabolism error [ICD-11: 5C52]
P11597 CETP_HUMAN Chronic arterial occlusive disease [ICD-11: BD4Z]
P11597 CETP_HUMAN Dyslipidemia [ICD-11: 5C80-5C81]
Q99814 EPAS1_HUMAN Adrenomedullary hyperfunction [ICD-11: 5A75]
Q99814 EPAS1_HUMAN Renal cell carcinoma [ICD-11: 2C90]
Q99814 EPAS1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q99814 EPAS1_HUMAN Brain cancer [ICD-11: 2A00]
Q99814 EPAS1_HUMAN Adrenomedullary hyperfunction [ICD-11: 5A75]
Q99814 EPAS1_HUMAN Brain cancer [ICD-11: 2A00]
Q99814 EPAS1_HUMAN Renal cell carcinoma [ICD-11: 2C90]
P09917 LOX5_HUMAN Asthma [ICD-11: CA23]
P09917 LOX5_HUMAN Filariasis [ICD-11: 1F66]
P09917 LOX5_HUMAN Thrombocytopenia [ICD-11: 3B64]
P09917 LOX5_HUMAN Lung cancer [ICD-11: 2C25]
P09917 LOX5_HUMAN Nasopharyngeal cancer [ICD-11: 2B6B]
P09917 LOX5_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P09917 LOX5_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P09917 LOX5_HUMAN Atopic eczema [ICD-11: EA80]
P09917 LOX5_HUMAN Carcinoid syndrome [ICD-11: 5B10]
P09917 LOX5_HUMAN Fungal infection [ICD-11: 1F29-1F2F]
P09917 LOX5_HUMAN Idiopathic interstitial pneumonitis [ICD-11: CB03]
P09917 LOX5_HUMAN Influenza [ICD-11: 1E30-1E32]
P09917 LOX5_HUMAN Pituitary gland disorder [ICD-11: 5A60-5A61]
P09917 LOX5_HUMAN Psoriasis [ICD-11: EA90]
P09917 LOX5_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P09917 LOX5_HUMAN Pain [ICD-11: MG30-MG3Z]
P09917 LOX5_HUMAN Respiratory system disease [ICD-11: CB40-CB7Z]
P09917 LOX5_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P09917 LOX5_HUMAN Chronic obstructive pulmonary disease [ICD-11: CA22]
P09917 LOX5_HUMAN Eczema [ICD-11: EA80-EA89]
P09917 LOX5_HUMAN Pruritus [ICD-11: EC90]
P09917 LOX5_HUMAN Thrombosis [ICD-11: DB61-GB90]
P09917 LOX5_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
P09917 LOX5_HUMAN Allergic/hypersensitivity disorder [ICD-11: 4A80-4A8Z]
P09917 LOX5_HUMAN Arterial occlusive disease [ICD-11: BD40]
P09917 LOX5_HUMAN Malaria [ICD-11: 1F40-1F45]
P09917 LOX5_HUMAN Asthma [ICD-11: CA23]
P09917 LOX5_HUMAN Pain [ICD-11: MG30-MG3Z]
P09917 LOX5_HUMAN Rheumatoid arthritis [ICD-11: FA20]