Basic Information

Terpenoid ID TKC044763
Cell line 2
Protein target 1
DiseaseNCIT 2
ORDO 0
ICD 21

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC044763 PANC-1 Panc-1; PANC.1; Panc 1; PanC1; Panc1; PANC1; Panc-1-P 21.0 uM PC50 C9120
TKC044763 MIA PaCa-2 MIA-PaCa-2; MIA-PACA-2; MIA-Pa-Ca-2; MIA Paca2; MIA PaCa2; MiaPaCa-2; MIAPACA-2; MiaPaca.2; MiaPaCa2; Miapaca2; MIAPaCa2; MIAPACA2; Mia PACA 2; MIAPaCa-2; PaCa2; MiaPaCa 11.0 uM PC50 C9120
TKC044763 CAPAN-1 CaPan-1; CAPAN-1; Capan 1; CAPAN 1; Capan1; CAPAN1 11.0 uM PC50 C9120
TKC044763 PSN1 PSN-1 20.0 uM PC50 C8294

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC044763 P31749 RAC-alpha serine/threonine-protein kinase AKT1 100 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P31749 AKT1_HUMAN Brain cancer [ICD-11: 2A00]
P31749 AKT1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P31749 AKT1_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P31749 AKT1_HUMAN Colorectal cancer [ICD-11: 2B91]
P31749 AKT1_HUMAN Diffuse large B-cell lymphoma [ICD-11: 2A81]
P31749 AKT1_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P31749 AKT1_HUMAN Prostate cancer [ICD-11: 2C82]
P31749 AKT1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P31749 AKT1_HUMAN Stomach cancer [ICD-11: 2B72]
P31749 AKT1_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P31749 AKT1_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P31749 AKT1_HUMAN Injury [ICD-11: NA00-ND5Z]
P31749 AKT1_HUMAN Leukaemia [ICD-11: 2A60-2B33]
P31749 AKT1_HUMAN Lymphoma [ICD-11: 2A80-2A86]
P31749 AKT1_HUMAN Multiple myeloma [ICD-11: 2A83]
P31749 AKT1_HUMAN Ovarian cancer [ICD-11: 2C73]
P31749 AKT1_HUMAN Overgrowth syndrome [ICD-11: LD2C]
P31749 AKT1_HUMAN Pancreatic cancer [ICD-11: 2C10]
P31749 AKT1_HUMAN Parkinsonism [ICD-11: 8A00]
P31749 AKT1_HUMAN Renal cell carcinoma [ICD-11: 2C90]
P31749 AKT1_HUMAN Arterial occlusive disease [ICD-11: BD40]