Basic Information

Terpenoid ID TKC022961
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 0

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC022961 HepG2 69.0 % Survival C3728 Orphanet_449
TKC022961 BV-2 BV2 7300.0 nM IC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC022961 P23219 Prostaglandin G/H synthase 1 PTGS1 44 % Inhibition
TKC022961 O42275 Acetylcholinesterase ache 11 % Inhibition
TKC022961 P03372 Estrogen receptor ESR1 54 % Activity
TKC022961 P35354 Prostaglandin G/H synthase 2 PTGS2 <30 % Inhibition
TKC022961 P81908 Cholinesterase BCHE -5 % Inhibition
TKC022961 Q92830 Histone acetyltransferase KAT2A KAT2A 39811 nM Potency
TKC022961 P19821 DNA polymerase I, thermostable polA 47800 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P23219 PGH1_HUMAN Alzheimer disease [ICD-11: 8A20]
P23219 PGH1_HUMAN Endometriosis [ICD-11: GA10]
P23219 PGH1_HUMAN Eye anterior segment structural developmental anomaly [ICD-11: LA11]
P23219 PGH1_HUMAN Female pelvic pain [ICD-11: GA34]
P23219 PGH1_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P23219 PGH1_HUMAN Indeterminate colitis [ICD-11: DD72]
P23219 PGH1_HUMAN Nutritional deficiency [ICD-11: 5B50-5B71]
P23219 PGH1_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
P23219 PGH1_HUMAN Pain [ICD-11: MG30-MG3Z]
P23219 PGH1_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P23219 PGH1_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P23219 PGH1_HUMAN Seborrhoeic dermatitis [ICD-11: EA81]
P23219 PGH1_HUMAN Tuberculosis [ICD-11: 1B10-1B12]
P23219 PGH1_HUMAN Ulcerative colitis [ICD-11: DD71]
P23219 PGH1_HUMAN Shoulder lesion [ICD-11: FB53]
P23219 PGH1_HUMAN Soft tissue disorder [ICD-11: FB56]
P23219 PGH1_HUMAN Colorectal cancer [ICD-11: 2B91]
P23219 PGH1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P23219 PGH1_HUMAN Systemic sclerosis [ICD-11: 4A42]
P23219 PGH1_HUMAN Vasculitis [ICD-11: 4A44]
P23219 PGH1_HUMAN Ataxic disorder [ICD-11: 8A03]
P23219 PGH1_HUMAN Muscular dystrophy [ICD-11: 8C70]
P23219 PGH1_HUMAN Neuropathy [ICD-11: 8C0Z]
P23219 PGH1_HUMAN Fever [ICD-11: MG26]
P23219 PGH1_HUMAN Gout [ICD-11: FA25]
P23219 PGH1_HUMAN Sensation disturbance [ICD-11: MB40]
P23219 PGH1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P23219 PGH1_HUMAN General pain disorder [ICD-11: 8E43]
P03372 ESR1_HUMAN Acne vulgaris [ICD-11: ED80]
P03372 ESR1_HUMAN Acquired prion disease [ICD-11: 8E01]
P03372 ESR1_HUMAN Adrenal cancer [ICD-11: 2D11]
P03372 ESR1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P03372 ESR1_HUMAN Contraceptive management [ICD-11: QA21]
P03372 ESR1_HUMAN Dyspareunia [ICD-11: GA12]
P03372 ESR1_HUMAN Female infertility [ICD-11: GA31]
P03372 ESR1_HUMAN Low bone mass disorder [ICD-11: FB83]
P03372 ESR1_HUMAN Male infertility [ICD-11: GB04]
P03372 ESR1_HUMAN Menopausal disorder [ICD-11: GA30]
P03372 ESR1_HUMAN Menstrual cycle bleeding disorder [ICD-11: GA20]
P03372 ESR1_HUMAN Multiple sclerosis [ICD-11: 8A40]
P03372 ESR1_HUMAN Pituitary gland disorder [ICD-11: 5A60-5A61]
P03372 ESR1_HUMAN Skeletal anomaly [ICD-11: LD24]
P03372 ESR1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P03372 ESR1_HUMAN Vaginitis [ICD-11: GA02]
P03372 ESR1_HUMAN Virus infection [ICD-11: 1A24-1D9Z]
P03372 ESR1_HUMAN Endometriosis [ICD-11: GA10]
P03372 ESR1_HUMAN Female genital tract noninflammatory disorder [ICD-11: GA1Y]
P03372 ESR1_HUMAN Female pelvic pain [ICD-11: GA34]
P03372 ESR1_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P03372 ESR1_HUMAN Breast in situ carcinoma [ICD-11: 2E65]
P03372 ESR1_HUMAN Diabetes mellitus [ICD-11: 5A10]
P03372 ESR1_HUMAN Prostate cancer [ICD-11: 2C82]
P03372 ESR1_HUMAN Brain cancer [ICD-11: 2A00]
P03372 ESR1_HUMAN Metastatic tumour [ICD-11: 2D50-2E2Z]
P03372 ESR1_HUMAN Irregularities [ICD-11: N.A.]
P03372 ESR1_HUMAN Trematode disease [ICD-11: 1F8Y]
P03372 ESR1_HUMAN Pain [ICD-11: MG30-MG3Z]
P03372 ESR1_HUMAN Eye disorder [ICD-11: 9A01-9A0Z]
P03372 ESR1_HUMAN Dissociative neurological symptom disorder [ICD-11: 6B60]
P03372 ESR1_HUMAN Thrombocytopenia [ICD-11: 3B64]
P03372 ESR1_HUMAN Atrophy [ICD-11: 9A2Y-9C40]
P03372 ESR1_HUMAN Joint pain [ICD-11: ME82]
P03372 ESR1_HUMAN Sexual dysfunction [ICD-11: HA00-HA01]
P03372 ESR1_HUMAN Leukaemia [ICD-11: 2A60-2B33]
P35354 PGH2_HUMAN Alzheimer disease [ICD-11: 8A20]
P35354 PGH2_HUMAN Chronic pain [ICD-11: MG30]
P35354 PGH2_HUMAN Endometriosis [ICD-11: GA10]
P35354 PGH2_HUMAN Female pelvic pain [ICD-11: GA34]
P35354 PGH2_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P35354 PGH2_HUMAN Indeterminate colitis [ICD-11: DD72]
P35354 PGH2_HUMAN Knee osteoarthritis [ICD-11: FA01]
P35354 PGH2_HUMAN Migraine [ICD-11: 8A80]
P35354 PGH2_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
P35354 PGH2_HUMAN Pain [ICD-11: MG30-MG3Z]
P35354 PGH2_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P35354 PGH2_HUMAN Tuberculosis [ICD-11: 1B10-1B12]
P35354 PGH2_HUMAN Shoulder lesion [ICD-11: FB53]
P35354 PGH2_HUMAN Soft tissue disorder [ICD-11: FB56]
P35354 PGH2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P35354 PGH2_HUMAN Asthma [ICD-11: CA23]
P35354 PGH2_HUMAN Gout [ICD-11: FA25]
P35354 PGH2_HUMAN General pain disorder [ICD-11: 8E43]
P35354 PGH2_HUMAN Lupus erythematosus [ICD-11: 4A40]
P35354 PGH2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P35354 PGH2_HUMAN Large intestine polyp [ICD-11: DB35]
P35354 PGH2_HUMAN Lung cancer [ICD-11: 2C25]
P35354 PGH2_HUMAN Pancreatic cancer [ICD-11: 2C10]
P35354 PGH2_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P35354 PGH2_HUMAN Colorectal cancer [ICD-11: 2B91]
P35354 PGH2_HUMAN Fever [ICD-11: MG26]
P35354 PGH2_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]