Basic Information

Terpenoid ID TKC021477
Chirality TKC147252
Cell line 0
Protein target 15
DiseaseNCIT 0
ORDO 0
ICD 6

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC021477 O75164 Lysine-specific demethylase 4A KDM4A 35481 nM Potency
TKC021477 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 7943 nM Potency
TKC021477 Q9UBT6 DNA polymerase kappa POLK 35481 nM Potency
TKC021477 Q9UNA4 DNA polymerase iota POLI 33588 nM Potency
TKC021477 P39748 Flap endonuclease 1 FEN1 84921 nM Potency
TKC021477 P83916 Chromobox protein homolog 1 CBX1 19953 nM Potency
TKC021477 Q01196 Runt-related transcription factor 1 RUNX1 14125 nM Potency
TKC021477 Q92830 Histone acetyltransferase KAT2A KAT2A 8913 nM Potency
TKC021477 P06746 DNA polymerase beta POLB 19953 nM Potency
TKC021477 Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B BAZ2B 28184 nM Potency
TKC021477 Q9Y253 DNA polymerase eta POLH 17783 nM Potency
TKC021477 O94925 Glutaminase kidney isoform, mitochondrial GLS 35481 nM Potency
TKC021477 P07378 Phosphoglycerate kinase, glycosomal 28184 nM Potency
TKC021477 Q4GZG4 Phosphoglycerate kinase PGKC 8191 nM Potency
TKC021477 Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 CTDSP1 3194 nM IC50
TKC021477 Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 CTDSP1 3194 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]
P06746 DPOLB_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]