Basic Information

Terpenoid ID TKC105717
Cell line 0
Protein target 8
DiseaseNCIT 0
ORDO 0
ICD 15

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC105717 P10636 Microtubule-associated protein tau MAPT 19953 nM Potency
TKC105717 P84022 Mothers against decapentaplegic homolog 3 SMAD3 35481 nM Potency
TKC105717 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 12589 nM Potency
TKC105717 Q01196 Runt-related transcription factor 1 RUNX1 39811 nM Potency
TKC105717 P63096 Guanine nucleotide-binding protein G GNAI1 1122 nM Potency
TKC105717 P06746 DNA polymerase beta POLB 44668 nM Potency
TKC105717 Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B BAZ2B 79433 nM Potency
TKC105717 Q8WZA2 Rap guanine nucleotide exchange factor 4 RAPGEF4 11220 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]
P06746 DPOLB_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]