Basic Information

Terpenoid ID TKC103150
Chirality TKC035984
Cell line 0
Protein target 24
DiseaseNCIT 0
ORDO 0
ICD 38

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC103150 HEK293 3162.0 nM Potency

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC103150 Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH2 22387 nM Potency
TKC103150 P00352 Retinal dehydrogenase 1 ALDH1A1 39811 nM Potency
TKC103150 P10636 Microtubule-associated protein tau MAPT 126 nM Potency
TKC103150 Q16637 Survival motor neuron protein SMN1,SMN2 17783 nM Potency
TKC103150 Q16637 Survival motor neuron protein SMN1,SMN2 17783 nM Potency
TKC103150 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 31623 nM Potency
TKC103150 Q9UNA4 DNA polymerase iota POLI 19953 nM Potency
TKC103150 O75496 Geminin GMNN 6310 nM Potency
TKC103150 O89049 Thioredoxin reductase 1, cytoplasmic Txnrd1 28184 nM Potency
TKC103150 P28482 Mitogen-activated protein kinase 1 MAPK1 3548 nM Potency
TKC103150 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 EHMT2 10000 nM Potency
TKC103150 P54132 Bloom syndrome protein BLM 12589 nM Potency
TKC103150 Q01453 Peripheral myelin protein 22 PMP22 60 nM Potency
TKC103150 Q6W5P4 Neuropeptide S receptor NPSR1 1259 nM Potency
TKC103150 O00255 Menin MEN1 10000 nM Potency
TKC103150 P02791 Ferritin light chain FTL 12589 nM Potency
TKC103150 P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] HPGD 22387 nM Potency
TKC103150 P25779 Cruzipain 15849 nM Potency
TKC103150 P06746 DNA polymerase beta POLB 22387 nM Potency
TKC103150 Q9Y253 DNA polymerase eta POLH 17783 nM Potency
TKC103150 P02545 Prelamin-A/C LMNA 50 nM Potency
TKC103150 Q194T2 Non-structural protein 1 NS1 8913 nM Potency
TKC103150 P10253 Lysosomal alpha-glucosidase GAA 14125 nM Potency
TKC103150 P06280 Alpha-galactosidase A GLA 14125 nM Potency
TKC103150 Q99549 M-phase phosphoprotein 8 MPHOSPH8 1000 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q12809 KCNH2_HUMAN Heart failure [ICD-11: BD10-BD1Z]
Q12809 KCNH2_HUMAN Sleep-wake disorder [ICD-11: 7A00-7B2Z]
Q12809 KCNH2_HUMAN Malaria [ICD-11: 1F40-1F45]
Q12809 KCNH2_HUMAN Multiple sclerosis [ICD-11: 8A40]
Q12809 KCNH2_HUMAN Pain [ICD-11: MG30-MG3Z]
Q12809 KCNH2_HUMAN Cardiac arrhythmia [ICD-11: BC9Z]
Q12809 KCNH2_HUMAN Angina pectoris [ICD-11: BA40]
Q12809 KCNH2_HUMAN Genetic cardiac arrhythmia [ICD-11: BC65]
Q12809 KCNH2_HUMAN Ovarian cancer [ICD-11: 2C73]
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]
P28482 MK01_HUMAN Melanoma [ICD-11: 2C30]
P28482 MK01_HUMAN Pancreatic cancer [ICD-11: 2C10]
P28482 MK01_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P28482 MK01_HUMAN Arteries/arterioles disorder [ICD-11: BD52]
P28482 MK01_HUMAN Allergic/hypersensitivity disorder [ICD-11: 4A80-4A8Z]
P28482 MK01_HUMAN Transplant rejection [ICD-11: NE84]
P28482 MK01_HUMAN Mature T-cell lymphoma [ICD-11: 2A90]
P28482 MK01_HUMAN Rheumatoid arthritis [ICD-11: FA20]
Q96KQ7 EHMT2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96KQ7 EHMT2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q96KQ7 EHMT2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P25779 CYSP_TRYCR Parasitic worm infestation [ICD-11: 1F90]
P25779 CYSP_TRYCR Malaria [ICD-11: 1F40-1F45]
P06746 DPOLB_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P10253 LYAG_HUMAN Inborn carbohydrate metabolism error [ICD-11: 5C51]
P06280 AGAL_HUMAN Lysosomal disease [ICD-11: 5C56]