Basic Information
| Terpenoid ID | TKC132609 |
|
| Cell line | 0 | |
| Protein target | 15 | |
| DiseaseNCIT | 0 | |
| ORDO | 0 | |
| ICD | 47 |
| Terpenoid ID | TKC132609 |
|
| Cell line | 0 | |
| Protein target | 15 | |
| DiseaseNCIT | 0 | |
| ORDO | 0 | |
| ICD | 47 |
| ID | Cell Line | Synonyms | Value | Unit | Type | NCIt | ORDO |
|---|---|---|---|---|---|---|---|
| TKC132609 | SNB-75 | SNB.75; SNB75; Surgical Neurology Branch-75 | 10000.0 | nM | GI50 | C3058 | Orphanet_360 |
| TKC132609 | HCT-15 | HCT-15; HCT.15; HCT15 | 10000.0 | nM | GI50 | C4349 | |
| TKC132609 | SN12C | SN-12C | 10000.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC132609 | MDA-N | MDAN | 10000.0 | nM | GI50 | C3802 | |
| TKC132609 | NCI-H23 | NCI.H23; NCI H23; H-23; H23; NCIH23 | 4159.0 | nM | GI50 | C3512 | |
| TKC132609 | UO-31 | UO.31; UO31; U031 | 9.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC132609 | HOP-92 | HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 | 10000.0 | nM | GI50 | C2926 | |
| TKC132609 | HL-60 | HL 60; HL.60 HL60; Human Leukemia-60 | 3656.0 | nM | GI50 | C9154 | Orphanet_519 |
| TKC132609 | SK-MEL-5 | SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel | 10000.0 | nM | GI50 | C3510 | |
| TKC132609 | SF-539 | SF-539; SF-539 BT; SF.539; SF 539 | 10000.0 | nM | GI50 | C3796 | Orphanet_251576 |
| TKC132609 | Malme-3M | MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer | 10000.0 | nM | GI50 | C3224 | |
| TKC132609 | K562 | K562; K.562; K 562; KO; GM05372; GM05372E | 10000.0 | nM | GI50 | C9110 | Orphanet_521 |
| TKC132609 | OVCAR-3 | Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 | 10000.0 | nM | GI50 | C105555 | |
| TKC132609 | MOLT-4 | Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D | 10000.0 | nM | GI50 | C9142 | Orphanet_99861 |
| TKC132609 | HOP-62 | HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 | 10000.0 | nM | GI50 | C3512 | |
| TKC132609 | NCI/ADR-RES | NCI/ADR-RES; NCI.ADR.RES; NCIADR.RES; NCI/ADRRES; NCIADRRES; ADR-RES; MCF-7/ADR; MCF-7/ADR-RES; MCF-7/AdrR; MCF-7/Adr; MCF-7/adr; MCF-7ADR; MCF7-ADR; MCF7ADR; OVCAR-8/ADR; OVCAR8/ADR | 10000.0 | nM | GI50 | C105555 | |
| TKC132609 | U-251 | U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) | 10000.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC132609 | OVCAR-8 | OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 | 10000.0 | nM | GI50 | C105555 | |
| TKC132609 | SNB-19 | SNB.19; SNB19; Surgical Neurology Branch-19 | 10000.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC132609 | SR | SR-786; SR786 | 5728.0 | nM | GI50 | C37193 | Orphanet_300895 |
| TKC132609 | TK-10 | TK.10; TK 10; TK10 | 10000.0 | nM | GI50 | C4033 | Orphanet_319276 |
| TKC132609 | SW-620 | SW-620; SW 620; SW.620 | 10000.0 | nM | GI50 | C4349 | |
| TKC132609 | KM12 | KM-12; KM.12 | 10000.0 | nM | GI50 | C4910 | |
| TKC132609 | NCI-H322M | NCI.H322M; H322M; H-322M; H-322m | 10000.0 | nM | GI50 | C2923 | |
| TKC132609 | RPMI-8226 | RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson | 10000.0 | nM | GI50 | C3242 | Orphanet_29073 |
| TKC132609 | OVCAR-4 | OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 | 10000.0 | nM | GI50 | C105555 | |
| TKC132609 | LOX IMVI | LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX | 10000.0 | nM | GI50 | C3802 | |
| TKC132609 | SK-MEL-2 | SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 | 10000.0 | nM | GI50 | C3224 | |
| TKC132609 | HCC 2998 | HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 | 10000.0 | nM | GI50 | C4349 | |
| TKC132609 | A549 | 10000.0 | nM | GI50 | C3512 | ||
| TKC132609 | HCT-116 | HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 | 10000.0 | nM | GI50 | C4910 | |
| TKC132609 | SF-268 | SF-268; SF.268; SF 268 | 10000.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC132609 | EKVX | 10000.0 | nM | GI50 | C3512 | ||
| TKC132609 | PC-3 | PC3; PC.3 | 10000.0 | nM | GI50 | C4863 | |
| TKC132609 | MCF7 | 10000.0 | nM | GI50 | C4194 | ||
| TKC132609 | SK-OV-3 | SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 | 10000.0 | nM | GI50 | C7978 | |
| TKC132609 | T47D | 10000.0 | nM | GI50 | C4194 | ||
| TKC132609 | UACC-62 | UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 | 10000.0 | nM | GI50 | C3224 | |
| TKC132609 | MDA-MB-435 | MDA-MB435; MDAMB435; MDA.MB.435; MDA-435; MDA 435; MDA435; MD Anderson-Metastatic Breast-435 | 10000.0 | nM | GI50 | C3802 | |
| TKC132609 | SF-295 | SF-295; SF.295; SF 295 | 10000.0 | nM | GI50 | C3058 | Orphanet_360 |
| TKC132609 | IGROV-1 | Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P | 10000.0 | nM | GI50 | C7979 | Orphanet_454723 |
| TKC132609 | Hs-578T | HS 578T; Hs-578T; HS-578T; Hs_578t; Hs-578-T; HS-578-T; Hs 578.T; HS578T; Hs578T; Hs578t; HS0578T; 578T; HS578; Hs578; Homo sapiens No. 578, tumor cells | 10000.0 | nM | GI50 | C4194 | |
| TKC132609 | 786-0 | 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT | 10000.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC132609 | CCRF-CEM | CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C | 4688.0 | nM | GI50 | C7953 | Orphanet_99861 |
| TKC132609 | HT-29 | HT 29; HT29 | 10000.0 | nM | GI50 | C4349 | |
| TKC132609 | NCI-H226 | NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 | 10000.0 | nM | GI50 | C45662 | Orphanet_50251 |
| TKC132609 | SK-MEL-28 | SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 | 10000.0 | nM | GI50 | C3510 | |
| TKC132609 | RXF 393 | RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL | 10000.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC132609 | COLO 205 | Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 | 10000.0 | nM | GI50 | C4349 |
| ID | Uniport | Pref_name | Gene name | value | unit | type |
|---|---|---|---|---|---|---|
| TKC132609 | Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | TDP1 | 23109 | nM | Potency |
| TKC132609 | O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | IDH1 | 18356 | nM | Potency |
| TKC132609 | P43220 | Glucagon-like peptide 1 receptor | GLP1R | 8913 | nM | Potency |
| TKC132609 | P84022 | Mothers against decapentaplegic homolog 3 | SMAD3 | 35481 | nM | Potency |
| TKC132609 | Q06710 | Paired box protein Pax-8 | PAX8 | 5430 | nM | AC50 |
| TKC132609 | Q99700 | Ataxin-2 | ATXN2 | 39811 | nM | Potency |
| TKC132609 | Q962Y6 | Thioredoxin glutathione reductase | TGR | 39811 | nM | Potency |
| TKC132609 | O75496 | Geminin | GMNN | 23109 | nM | Potency |
| TKC132609 | P01215 | Glycoprotein hormones alpha chain | CGA | 891 | nM | Potency |
| TKC132609 | Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | APOBEC3G | 19953 | nM | Potency |
| TKC132609 | P83916 | Chromobox protein homolog 1 | CBX1 | 100000 | nM | Potency |
| TKC132609 | P08659 | Luciferin 4-monooxygenase | 23934 | nM | Potency | |
| TKC132609 | P51450 | Nuclear receptor ROR-gamma | Rorc | 11220 | nM | Potency |
| TKC132609 | P04637 | Cellular tumor antigen p53 | TP53 | 11220 | nM | Potency |
| TKC132609 | P10145 | Interleukin-8 | CXCL8 | 7490 | nM | IC50 |
| Uniport ID | Uniport Name | ICD-11 |
|---|---|---|
| O75874 | IDHC_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| O75874 | IDHC_HUMAN | Liver cancer [ICD-11: 2C12] |
| O75874 | IDHC_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| O75874 | IDHC_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| O75874 | IDHC_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| O75874 | IDHC_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P43220 | GLP1R_HUMAN | Cardiovascular disease [ICD-11: BA00-BE2Z] |
| P43220 | GLP1R_HUMAN | Obesity [ICD-11: 5B80-5B81] |
| P43220 | GLP1R_HUMAN | Type 2 diabetes mellitus [ICD-11: 5A11] |
| P43220 | GLP1R_HUMAN | Type-1/2 diabete [ICD-11: 5A10-5A11] |
| P43220 | GLP1R_HUMAN | Acute diabete complication [ICD-11: 5A2Y] |
| P43220 | GLP1R_HUMAN | Diabetes mellitus [ICD-11: 5A10] |
| P43220 | GLP1R_HUMAN | Dyspepsia [ICD-11: MD92] |
| P43220 | GLP1R_HUMAN | Irritable bowel syndrome [ICD-11: DD91] |
| P43220 | GLP1R_HUMAN | Intracranial injury [ICD-11: NA07] |
| P43220 | GLP1R_HUMAN | Non-alcoholic fatty liver disease [ICD-11: DB92] |
| P84022 | SMAD3_HUMAN | Herpes simplex infection [ICD-11: 1F00] |
| P84022 | SMAD3_HUMAN | Kidney fibrosis [ICD-11: GC01] |
| P04637 | P53_HUMAN | Arterial occlusive disease [ICD-11: BD40] |
| P04637 | P53_HUMAN | Lip/oral cavity/pharynx neoplasm [ICD-11: 2B6E] |
| P04637 | P53_HUMAN | Metastatic liver/bile duct neoplasm [ICD-11: 2D80] |
| P04637 | P53_HUMAN | Transplant rejection [ICD-11: NE84] |
| P04637 | P53_HUMAN | Ovarian dysfunction [ICD-11: 5A80] |
| P04637 | P53_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P04637 | P53_HUMAN | Bladder cancer [ICD-11: 2C94] |
| P04637 | P53_HUMAN | Brain cancer [ICD-11: 2A00] |
| P04637 | P53_HUMAN | Colorectal cancer [ICD-11: 2B91] |
| P04637 | P53_HUMAN | Esophageal cancer [ICD-11: 2B70] |
| P04637 | P53_HUMAN | Head and neck cancer [ICD-11: 2D42] |
| P04637 | P53_HUMAN | Mature B-cell leukaemia [ICD-11: 2A82] |
| P04637 | P53_HUMAN | Myelodysplastic syndrome [ICD-11: 2A37] |
| P04637 | P53_HUMAN | Ovarian cancer [ICD-11: 2C73] |
| P04637 | P53_HUMAN | Pancreatic cancer [ICD-11: 2C10] |
| P04637 | P53_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P04637 | P53_HUMAN | Stomach cancer [ICD-11: 2B72] |
| P04637 | P53_HUMAN | Cervical cancer [ICD-11: 2C77] |
| P04637 | P53_HUMAN | Endometrial cancer [ICD-11: 2C76] |
| P04637 | P53_HUMAN | Fallopian tube cancer [ICD-11: 2C74] |
| P04637 | P53_HUMAN | Liposarcoma [ICD-11: 2B59] |
| P04637 | P53_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| P04637 | P53_HUMAN | Peritoneal cancer [ICD-11: 2C51] |
| P04637 | P53_HUMAN | Toxicity [ICD-11: N.A.] |
| P04637 | P53_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P04637 | P53_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P04637 | P53_HUMAN | Kidney failure [ICD-11: GB60-GB6Z] |
| P04637 | P53_HUMAN | Hearing disorder [ICD-11: AB50-AB57] |
| P10145 | IL8_HUMAN | Pain [ICD-11: MG30-MG3Z] |
| P10145 | IL8_HUMAN | COVID-19 [ICD-11: 1D6Y] |
| P10145 | IL8_HUMAN | Melanoma [ICD-11: 2C30] |
| P10145 | IL8_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P10145 | IL8_HUMAN | Diabetes mellitus [ICD-11: 5A10] |