Basic Information

Terpenoid ID TKC103074
Cell line 0
Protein target 2
DiseaseNCIT 0
ORDO 0
ICD 13

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC103074 H9 HT clone H9; HT(H9); H 9; H-9 4000.0 nM EC50 C3366 Orphanet_3162

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC103074 P05771 Protein kinase C beta type PRKCB >150000 nM IC50
TKC103074 Q05655 Protein kinase C delta type PRKCD 49000 nM IC50
TKC103074 Q02156 Protein kinase C epsilon type PRKCE >150000 nM IC50
TKC103074 Q96RI1 Bile acid receptor NR1H4 0 nM EC50
TKC103074 Q8TDU6 G-protein coupled bile acid receptor 1 GPBAR1 >0 % Efficacy

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P05771 KPCB_HUMAN Brain cancer [ICD-11: 2A00]
P05771 KPCB_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P05771 KPCB_HUMAN Diffuse large B-cell lymphoma [ICD-11: 2A81]
P05771 KPCB_HUMAN Lymphoma [ICD-11: 2A80-2A86]
P05771 KPCB_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P05771 KPCB_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P05771 KPCB_HUMAN Transplant rejection [ICD-11: NE84]
P05771 KPCB_HUMAN Mature B-cell leukaemia [ICD-11: 2A82]
P05771 KPCB_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P05771 KPCB_HUMAN Human immunodeficiency virus disease [ICD-11: 1C60-1C62]
Q05655 KPCD_HUMAN Myocardial infarction [ICD-11: BA41-BA43]
Q05655 KPCD_HUMAN Human immunodeficiency virus disease [ICD-11: 1C60-1C62]
Q05655 KPCD_HUMAN Human immunodeficiency virus disease [ICD-11: 1C60-1C62]
Q02156 KPCE_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
Q02156 KPCE_HUMAN Liver vascular disorder [ICD-11: DB98]
Q02156 KPCE_HUMAN Malaria [ICD-11: 1F40-1F45]
Q02156 KPCE_HUMAN Alzheimer disease [ICD-11: 8A20]
Q02156 KPCE_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q02156 KPCE_HUMAN Human immunodeficiency virus disease [ICD-11: 1C60-1C62]
Q96RI1 NR1H4_HUMAN Autoimmune liver disease [ICD-11: DB96]
Q96RI1 NR1H4_HUMAN Cholelithiasis [ICD-11: DC11]
Q96RI1 NR1H4_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
Q96RI1 NR1H4_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
Q96RI1 NR1H4_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96RI1 NR1H4_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q96RI1 NR1H4_HUMAN Chronic kidney disease [ICD-11: GB61]
Q96RI1 NR1H4_HUMAN Skeletal anomaly [ICD-11: LD24]
Q96RI1 NR1H4_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
Q96RI1 NR1H4_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
Q96RI1 NR1H4_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
Q8TDU6 GPBAR_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
Q8TDU6 GPBAR_HUMAN Hepatic fibrosis/cirrhosis [ICD-11: DB93]
Q8TDU6 GPBAR_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]