Basic Information

Terpenoid ID TKC035208
Chirality TKC035211
Cell line 0
Protein target 9
DiseaseNCIT 0
ORDO 0
ICD 32

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC035208 NIH3T3 NIH/3T3; NIH-3T3; NIH3T3; 3T3; 3T3NIH; 3T3-Swiss; Swiss-3T3; Swiss/3T3; Swiss 3T3; Swiss3T3 13900.0 nM IC50
TKC035208 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 29200.0 nM IC50 C4863
TKC035208 PA-1 PA1; PA I; PAI 10600.0 nM IC50 C8114 Orphanet_180234
TKC035208 K562 K562; K.562; K 562; KO; GM05372; GM05372E 14500.0 nM IC50 C9110 Orphanet_521
TKC035208 MIA PaCa-2 MIA-PaCa-2; MIA-PACA-2; MIA-Pa-Ca-2; MIA Paca2; MIA PaCa2; MiaPaCa-2; MIAPACA-2; MiaPaca.2; MiaPaCa2; Miapaca2; MIAPaCa2; MIAPACA2; Mia PACA 2; MIAPaCa-2; PaCa2; MiaPaCa 17700.0 nM IC50 C9120
TKC035208 HBL-100 HBL 100; HBL100 10300.0 nM IC50
TKC035208 SW-620 SW-620; SW 620; SW.620 7800.0 nM IC50 C4349
TKC035208 KB KB (HeLa derivative); HeLa-KB; Strain KB 28900.0 nM IC50 C27677
TKC035208 A549 12300.0 nM IC50 C3512
TKC035208 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 2.0 ug ml-1 CD50 C105555
TKC035208 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 2.0 ug ml-1 CD50 C27677
TKC035208 HepG2 2.0 ug ml-1 CD50 C3728 Orphanet_449
TKC035208 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 2100.0 nM IC50 C9154 Orphanet_519
TKC035208 C6 C-6; C 6; RGC-6; RGC6; RGc6 4100.0 nM IC50 C64069

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC035208 P11473 Vitamin D3 receptor VDR 39811 nM Potency
TKC035208 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 89125 nM Potency
TKC035208 Q04206 Transcription factor p65 RELA 50 uM IC100
TKC035208 P03372 Estrogen receptor ESR1 39 % Activity
TKC035208 P0DTD1 Replicase polyprotein 1ab rep -8 % Inhibition
TKC035208 P35354 Prostaglandin G/H synthase 2 PTGS2 7 uM IC60
TKC035208 O00255 Menin MEN1 2818 nM Potency
TKC035208 P02791 Ferritin light chain FTL 39811 nM Potency
TKC035208 P46063 ATP-dependent DNA helicase Q1 RECQL 12589 nM Potency
TKC035208 O14746 Telomerase reverse transcriptase TERT 65000 nM IC50
TKC035208 P51450 Nuclear receptor ROR-gamma Rorc 15849 nM Potency
TKC035208 P0A749 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA >50000 nM IC50
TKC035208 P01103 Transcriptional activator Myb MYB 30660 nM IC50
TKC035208 Q9HVW7 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA >50000 nM IC50
TKC035208 P59540 Taste receptor type 2 member 46 TAS2R46 8600 nM EC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P11473 VDR_HUMAN Chronic kidney disease [ICD-11: GB61]
P11473 VDR_HUMAN Hair/hair growth developmental defect [ICD-11: LC30]
P11473 VDR_HUMAN Hyper-parathyroidism [ICD-11: 5A51]
P11473 VDR_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P11473 VDR_HUMAN Mineral deficiency [ICD-11: 5B5K]
P11473 VDR_HUMAN Psoriasis [ICD-11: EA90]
P11473 VDR_HUMAN Vitamin deficiency [ICD-11: 5B55-5B5F]
P11473 VDR_HUMAN Low bone mass disorder [ICD-11: FB83]
P11473 VDR_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11473 VDR_HUMAN Prostate cancer [ICD-11: 2C82]
P11473 VDR_HUMAN Prostate disease [ICD-11: GA91]
P11473 VDR_HUMAN Abnormal micturition [ICD-11: MF50]
P11473 VDR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11473 VDR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P11473 VDR_HUMAN Acne vulgaris [ICD-11: ED80]
P03372 ESR1_HUMAN Acne vulgaris [ICD-11: ED80]
P03372 ESR1_HUMAN Acquired prion disease [ICD-11: 8E01]
P03372 ESR1_HUMAN Adrenal cancer [ICD-11: 2D11]
P03372 ESR1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P03372 ESR1_HUMAN Contraceptive management [ICD-11: QA21]
P03372 ESR1_HUMAN Dyspareunia [ICD-11: GA12]
P03372 ESR1_HUMAN Female infertility [ICD-11: GA31]
P03372 ESR1_HUMAN Low bone mass disorder [ICD-11: FB83]
P03372 ESR1_HUMAN Male infertility [ICD-11: GB04]
P03372 ESR1_HUMAN Menopausal disorder [ICD-11: GA30]
P03372 ESR1_HUMAN Menstrual cycle bleeding disorder [ICD-11: GA20]
P03372 ESR1_HUMAN Multiple sclerosis [ICD-11: 8A40]
P03372 ESR1_HUMAN Pituitary gland disorder [ICD-11: 5A60-5A61]
P03372 ESR1_HUMAN Skeletal anomaly [ICD-11: LD24]
P03372 ESR1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P03372 ESR1_HUMAN Vaginitis [ICD-11: GA02]
P03372 ESR1_HUMAN Virus infection [ICD-11: 1A24-1D9Z]
P03372 ESR1_HUMAN Endometriosis [ICD-11: GA10]
P03372 ESR1_HUMAN Female genital tract noninflammatory disorder [ICD-11: GA1Y]
P03372 ESR1_HUMAN Female pelvic pain [ICD-11: GA34]
P03372 ESR1_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P03372 ESR1_HUMAN Breast in situ carcinoma [ICD-11: 2E65]
P03372 ESR1_HUMAN Diabetes mellitus [ICD-11: 5A10]
P03372 ESR1_HUMAN Prostate cancer [ICD-11: 2C82]
P03372 ESR1_HUMAN Brain cancer [ICD-11: 2A00]
P03372 ESR1_HUMAN Metastatic tumour [ICD-11: 2D50-2E2Z]
P03372 ESR1_HUMAN Irregularities [ICD-11: N.A.]
P03372 ESR1_HUMAN Trematode disease [ICD-11: 1F8Y]
P03372 ESR1_HUMAN Pain [ICD-11: MG30-MG3Z]
P03372 ESR1_HUMAN Eye disorder [ICD-11: 9A01-9A0Z]
P03372 ESR1_HUMAN Dissociative neurological symptom disorder [ICD-11: 6B60]
P03372 ESR1_HUMAN Thrombocytopenia [ICD-11: 3B64]
P03372 ESR1_HUMAN Atrophy [ICD-11: 9A2Y-9C40]
P03372 ESR1_HUMAN Joint pain [ICD-11: ME82]
P03372 ESR1_HUMAN Sexual dysfunction [ICD-11: HA00-HA01]
P03372 ESR1_HUMAN Leukaemia [ICD-11: 2A60-2B33]
P35354 PGH2_HUMAN Alzheimer disease [ICD-11: 8A20]
P35354 PGH2_HUMAN Chronic pain [ICD-11: MG30]
P35354 PGH2_HUMAN Endometriosis [ICD-11: GA10]
P35354 PGH2_HUMAN Female pelvic pain [ICD-11: GA34]
P35354 PGH2_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P35354 PGH2_HUMAN Indeterminate colitis [ICD-11: DD72]
P35354 PGH2_HUMAN Knee osteoarthritis [ICD-11: FA01]
P35354 PGH2_HUMAN Migraine [ICD-11: 8A80]
P35354 PGH2_HUMAN Osteoarthritis [ICD-11: FA00-FA05]
P35354 PGH2_HUMAN Pain [ICD-11: MG30-MG3Z]
P35354 PGH2_HUMAN Rheumatoid arthritis [ICD-11: FA20]
P35354 PGH2_HUMAN Tuberculosis [ICD-11: 1B10-1B12]
P35354 PGH2_HUMAN Shoulder lesion [ICD-11: FB53]
P35354 PGH2_HUMAN Soft tissue disorder [ICD-11: FB56]
P35354 PGH2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P35354 PGH2_HUMAN Asthma [ICD-11: CA23]
P35354 PGH2_HUMAN Gout [ICD-11: FA25]
P35354 PGH2_HUMAN General pain disorder [ICD-11: 8E43]
P35354 PGH2_HUMAN Lupus erythematosus [ICD-11: 4A40]
P35354 PGH2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P35354 PGH2_HUMAN Large intestine polyp [ICD-11: DB35]
P35354 PGH2_HUMAN Lung cancer [ICD-11: 2C25]
P35354 PGH2_HUMAN Pancreatic cancer [ICD-11: 2C10]
P35354 PGH2_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P35354 PGH2_HUMAN Colorectal cancer [ICD-11: 2B91]
P35354 PGH2_HUMAN Fever [ICD-11: MG26]
P35354 PGH2_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O14746 TERT_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
O14746 TERT_HUMAN Colorectal cancer [ICD-11: 2B91]
O14746 TERT_HUMAN Liver cancer [ICD-11: 2C12]
O14746 TERT_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O14746 TERT_HUMAN Pancreatic cancer [ICD-11: 2C10]
O14746 TERT_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
O14746 TERT_HUMAN Lung cancer [ICD-11: 2C25]
O14746 TERT_HUMAN Multiple myeloma [ICD-11: 2A83]
O14746 TERT_HUMAN Myelodysplastic syndrome [ICD-11: 2A37]
O14746 TERT_HUMAN Myeloproliferative neoplasm [ICD-11: 2A20]
O14746 TERT_HUMAN Thrombocytosis [ICD-11: 3B63]
O14746 TERT_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O14746 TERT_HUMAN Melanoma [ICD-11: 2C30]
O14746 TERT_HUMAN Ovarian cancer [ICD-11: 2C73]
O14746 TERT_HUMAN Glaucoma [ICD-11: 9C61]
O14746 TERT_HUMAN Head and neck cancer [ICD-11: 2D42]
O14746 TERT_HUMAN Liver cancer [ICD-11: 2C12]
O14746 TERT_HUMAN Brain cancer [ICD-11: 2A00]
O14746 TERT_HUMAN Prostate cancer [ICD-11: 2C82]
O14746 TERT_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P0A749 MURA_ECOLI Bacterial infection [ICD-11: 1A00-1C4Z]
P0A749 MURA_ECOLI Gram-positive bacterial infection [ICD-11: 1B74-1F40]