Basic Information
| Terpenoid ID | TKC032619 |
|
| Chirality | TKC149924 | |
| Cell line | 0 | |
| Protein target | 34 | |
| DiseaseNCIT | 0 | |
| ORDO | 0 | |
| ICD | 112 |
| Terpenoid ID | TKC032619 |
|
| Chirality | TKC149924 | |
| Cell line | 0 | |
| Protein target | 34 | |
| DiseaseNCIT | 0 | |
| ORDO | 0 | |
| ICD | 112 |
| ID | Cell Line | Synonyms | Value | Unit | Type | NCIt | ORDO |
|---|---|---|---|---|---|---|---|
| TKC032619 | HepG2 | 12589.0 | nM | Potency | C3728 | Orphanet_449 | |
| TKC032619 | UACC-62 | UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 | 16800.0 | nM | GI50 | C3224 | |
| TKC032619 | MCF7 | 16400.0 | nM | GI50 | C4194 | ||
| TKC032619 | SF-268 | SF-268; SF.268; SF 268 | 25100.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC032619 | SF-295 | SF-295; SF.295; SF 295 | 28900.0 | nM | GI50 | C3058 | Orphanet_360 |
| TKC032619 | SF-539 | SF-539; SF-539 BT; SF.539; SF 539 | 18900.0 | nM | GI50 | C3796 | Orphanet_251576 |
| TKC032619 | SNB-19 | SNB.19; SNB19; Surgical Neurology Branch-19 | 70900.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC032619 | SNB-75 | SNB.75; SNB75; Surgical Neurology Branch-75 | 48400.0 | nM | GI50 | C3058 | Orphanet_360 |
| TKC032619 | U-251 | U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) | 41500.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC032619 | Malme-3M | MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer | 13800.0 | nM | GI50 | C3224 | |
| TKC032619 | LOX IMVI | LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX | 8240.0 | nM | GI50 | C3802 | |
| TKC032619 | SK-MEL-2 | SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 | 16200.0 | nM | GI50 | C3224 | |
| TKC032619 | SK-MEL-28 | SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 | 21000.0 | nM | GI50 | C3510 | |
| TKC032619 | SK-MEL-5 | SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel | 17400.0 | nM | GI50 | C3510 | |
| TKC032619 | UACC-257 | UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 | 14400.0 | nM | GI50 | C3224 | |
| TKC032619 | SW-620 | SW-620; SW 620; SW.620 | 14500.0 | nM | GI50 | C4349 | |
| TKC032619 | KM12 | KM-12; KM.12 | 16200.0 | nM | GI50 | C4910 | |
| TKC032619 | HCT-15 | HCT-15; HCT.15; HCT15 | 10200.0 | nM | GI50 | C4349 | |
| TKC032619 | HCT-116 | HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 | 10800.0 | nM | GI50 | C4910 | |
| TKC032619 | HCC 2998 | HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 | 24100.0 | nM | GI50 | C4349 | |
| TKC032619 | COLO 205 | Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 | 14500.0 | nM | GI50 | C4349 | |
| TKC032619 | NCI-H522 | NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 | 5470.0 | nM | GI50 | C3512 | |
| TKC032619 | NCI-H460 | NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 | 18800.0 | nM | GI50 | C4450 | |
| TKC032619 | NCI-H322M | NCI.H322M; H322M; H-322M; H-322m | 21700.0 | nM | GI50 | C2923 | |
| TKC032619 | NCI-H23 | NCI.H23; NCI H23; H-23; H23; NCIH23 | 20200.0 | nM | GI50 | C3512 | |
| TKC032619 | NCI-H226 | NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 | 20500.0 | nM | GI50 | C45662 | Orphanet_50251 |
| TKC032619 | HOP-92 | HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 | 13500.0 | nM | GI50 | C2926 | |
| TKC032619 | HOP-62 | HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 | 49000.0 | nM | GI50 | C3512 | |
| TKC032619 | EKVX | 17300.0 | nM | GI50 | C3512 | ||
| TKC032619 | A549 | 29700.0 | nM | LC50 | C3512 | ||
| TKC032619 | RPMI-8226 | RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson | 8200.0 | nM | GI50 | C3242 | Orphanet_29073 |
| TKC032619 | CCRF-CEM | CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C | 9160.0 | nM | GI50 | C7953 | Orphanet_99861 |
| TKC032619 | HL-60(TB) | HL-60 (TB); HL-60-TB; HL-60TB; HL-60 TB | 5710.0 | nM | GI50 | C9154 | Orphanet_519 |
| TKC032619 | K562 | K562; K.562; K 562; KO; GM05372; GM05372E | 22600.0 | nM | GI50 | C9110 | Orphanet_521 |
| TKC032619 | MOLT-4 | Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D | 14300.0 | nM | GI50 | C9142 | Orphanet_99861 |
| TKC032619 | IGROV-1 | Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P | 21100.0 | nM | GI50 | C7979 | Orphanet_454723 |
| TKC032619 | OVCAR-3 | Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 | 17400.0 | nM | GI50 | C105555 | |
| TKC032619 | OVCAR-4 | OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 | 21500.0 | nM | GI50 | C105555 | |
| TKC032619 | OVCAR-5 | OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 | 34100.0 | nM | GI50 | C105555 | |
| TKC032619 | OVCAR-8 | OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 | 17100.0 | nM | GI50 | C105555 | |
| TKC032619 | NCI/ADR-RES | NCI/ADR-RES; NCI.ADR.RES; NCIADR.RES; NCI/ADRRES; NCIADRRES; ADR-RES; MCF-7/ADR; MCF-7/ADR-RES; MCF-7/AdrR; MCF-7/Adr; MCF-7/adr; MCF-7ADR; MCF7-ADR; MCF7ADR; OVCAR-8/ADR; OVCAR8/ADR | 15000.0 | nM | GI50 | C105555 | |
| TKC032619 | SK-OV-3 | SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 | 54700.0 | nM | GI50 | C7978 | |
| TKC032619 | A498 | A498 | 7040.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC032619 | CAKI-1 | CAL 1; Centre Antoine Lacassagne-1 | 9350.0 | nM | GI50 | C3224 | |
| TKC032619 | RXF 393 | RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL | 12200.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC032619 | SN12C | SN-12C | 22800.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC032619 | UO-31 | UO.31; UO31; U031 | 41900.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC032619 | PC-3 | PC3; PC.3 | 20500.0 | nM | LC50 | C4863 | |
| TKC032619 | MDA-MB-231 | MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 | 18300.0 | nM | LC50 | C5214 | |
| TKC032619 | MOLM-13 | MOLM13; Molm13; Molm 13 | 10000.0 | nM | IC50 | C9154 | Orphanet_519 |
| TKC032619 | EOL1 | EOL-1; EOL1; EoL-1-cell; EoL-1 cell; AML-EOL-1 | 7500.0 | nM | IC50 | C4563 | Orphanet_168940 |
| TKC032619 | JeKo-1 | Jeko-1; JEKO-1; JeKo 1; Jeko1; JEKO1; JEKO | 48.0 | % | Activity | C4337 | Orphanet_52416 |
| TKC032619 | Jurkat | JURKAT; JM; JM-Jurkat; Jurkat-FHCRC; Jurkat FHCRC; FHCRC-11; FHCRC subclone 11; FCCH1024 | 70.0 | % | Activity | C7953 | Orphanet_99861 |
| TKC032619 | HeLa | HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri | 35.0 | % | Activity | C27677 | |
| TKC032619 | SJSA-1 | SJSA1; SJSA; OsA-CL; OSA-CL; OsACL; OSACL; Os-A; OSA; OsA | 100.0 | % | Activity | C9145 | Orphanet_668 |
| TKC032619 | SK-N-MC | SKNMC; SK-NM-C; SK-NMC | 30.0 | % | Activity | C7542 | Orphanet_370348 |
| TKC032619 | Bel7402/5-FU | Bel7402/5-FU; BEL-7402/FU; Bel/5Fu | 12980.0 | nM | IC50 | C27677 | |
| TKC032619 | Bel-7402 | Bel-7402; BEL 7402; Bel 7402; BEL7402; Bel7402 | 8620.0 | nM | IC50 | C27677 | |
| TKC032619 | MEC1 | Mouse Epicardial Cells 1 | 6200.0 | nM | EC50 | ||
| TKC032619 | HL-60 | HL 60; HL.60 HL60; Human Leukemia-60 | 4688.0 | nM | GI50 | C9154 | Orphanet_519 |
| TKC032619 | HEK293 | 1413.0 | nM | Potency | |||
| TKC032619 | SH-SY5Y | SH-Sy5y; SHSY5Y; SHSY-5Y; SK-SH-SY5Y; SY5Y; SH-SY5Y Parental | 35481.0 | nM | Potency | C3270 | Orphanet_635 |
| TKC032619 | SN12C | SN-12C | 22856.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC032619 | NCI-H23 | NCI.H23; NCI H23; H-23; H23; NCIH23 | 20230.0 | nM | GI50 | C3512 | |
| TKC032619 | UO-31 | UO.31; UO31; U031 | 41976.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC032619 | HOP-92 | HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 | 13583.0 | nM | GI50 | C2926 | |
| TKC032619 | SF-539 | SF-539; SF-539 BT; SF.539; SF 539 | 18967.0 | nM | GI50 | C3796 | Orphanet_251576 |
| TKC032619 | SK-MEL-5 | SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel | 17458.0 | nM | GI50 | C3510 | |
| TKC032619 | Malme-3M | MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer | 13366.0 | nM | GI50 | C3224 | |
| TKC032619 | A498 | A498 | 7047.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC032619 | K562 | K562; K.562; K 562; KO; GM05372; GM05372E | 21827.0 | nM | GI50 | C9110 | Orphanet_521 |
| TKC032619 | OVCAR-3 | Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 | 18408.0 | nM | GI50 | C105555 | |
| TKC032619 | MOLT-4 | Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D | 14158.0 | nM | GI50 | C9142 | Orphanet_99861 |
| TKC032619 | NCI/ADR-RES | NCI/ADR-RES; NCI.ADR.RES; NCIADR.RES; NCI/ADRRES; NCIADRRES; ADR-RES; MCF-7/ADR; MCF-7/ADR-RES; MCF-7/AdrR; MCF-7/Adr; MCF-7/adr; MCF-7ADR; MCF7-ADR; MCF7ADR; OVCAR-8/ADR; OVCAR8/ADR | 15031.0 | nM | GI50 | C105555 | |
| TKC032619 | HOP-62 | HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 | 49091.0 | nM | GI50 | C3512 | |
| TKC032619 | U-251 | U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) | 41591.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC032619 | OVCAR-5 | OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 | 34198.0 | nM | GI50 | C105555 | |
| TKC032619 | OVCAR-8 | OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 | 16749.0 | nM | GI50 | C105555 | |
| TKC032619 | SNB-19 | SNB.19; SNB19; Surgical Neurology Branch-19 | 63680.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC032619 | DMS-273 | DMS-273; DMS273; Darmouth Medical School 273 | 24604.0 | nM | GI50 | C4917 | Orphanet_70573 |
| TKC032619 | SW-620 | SW-620; SW 620; SW.620 | 14757.0 | nM | GI50 | C4349 | |
| TKC032619 | M19-MEL | M-19; M19 | 14322.0 | nM | GI50 | C3802 | |
| TKC032619 | NCI-H522 | NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 | 5470.0 | nM | GI50 | C3512 | |
| TKC032619 | KM12 | KM-12; KM.12 | 16788.0 | nM | GI50 | C4910 | |
| TKC032619 | XF498 | XF-498; XF498 | 16866.0 | nM | GI50 | C3058 | Orphanet_360 |
| TKC032619 | NCI-H322M | NCI.H322M; H322M; H-322M; H-322m | 19498.0 | nM | GI50 | C2923 | |
| TKC032619 | RPMI-8226 | RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson | 8710.0 | nM | GI50 | C3242 | Orphanet_29073 |
| TKC032619 | OVCAR-4 | OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 | 21577.0 | nM | GI50 | C105555 | |
| TKC032619 | LOX IMVI | LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX | 8241.0 | nM | GI50 | C3802 | |
| TKC032619 | P388 | P-388 | 6592.0 | nM | GI50 | C21602 | |
| TKC032619 | SK-MEL-2 | SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 | 16218.0 | nM | GI50 | C3224 | |
| TKC032619 | A549 | 94624.0 | nM | GI50 | C3512 | ||
| TKC032619 | KM-20L2 | KM-20L2; KM 20L2; KM 2012 | 24774.0 | nM | GI50 | C4349 | |
| TKC032619 | HCC 2998 | HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 | 24155.0 | nM | GI50 | C4349 | |
| TKC032619 | SNB-75 | SNB.75; SNB75; Surgical Neurology Branch-75 | 48417.0 | nM | GI50 | C3058 | Orphanet_360 |
| TKC032619 | HCT-15 | HCT-15; HCT.15; HCT15 | 14655.0 | nM | GI50 | C4349 | |
| TKC032619 | HCT-116 | HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 | 10328.0 | nM | GI50 | C4910 | |
| TKC032619 | SF-268 | SF-268; SF.268; SF 268 | 23659.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC032619 | MCF7 | 16406.0 | nM | GI50 | C4194 | ||
| TKC032619 | EKVX | 17378.0 | nM | GI50 | C3512 | ||
| TKC032619 | DMS-114 | DMS-114; DMS114; Darmouth Medical School 114 | 45920.0 | nM | GI50 | C4917 | Orphanet_70573 |
| TKC032619 | SK-OV-3 | SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 | 54702.0 | nM | GI50 | C7978 | |
| TKC032619 | NCI-H460 | NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 | 18836.0 | nM | GI50 | C4450 | |
| TKC032619 | UACC-62 | UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 | 16827.0 | nM | GI50 | C3224 | |
| TKC032619 | CAKI-1 | CAL 1; Centre Antoine Lacassagne-1 | 9311.0 | nM | GI50 | C3224 | |
| TKC032619 | P388/ADR | 4842.0 | nM | GI50 | C21602 | ||
| TKC032619 | IGROV-1 | Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P | 21135.0 | nM | GI50 | C7979 | Orphanet_454723 |
| TKC032619 | SF-295 | SF-295; SF.295; SF 295 | 24774.0 | nM | GI50 | C3058 | Orphanet_360 |
| TKC032619 | UACC-257 | UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 | 14859.0 | nM | GI50 | C3224 | |
| TKC032619 | SNB-78 | SNB78; Surgical Neurology Branch-78 | 18155.0 | nM | GI50 | C3058 | Orphanet_360 |
| TKC032619 | CCRF-CEM | CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C | 8375.0 | nM | GI50 | C7953 | Orphanet_99861 |
| TKC032619 | DLD-1 | DLD 1; DLD1; CoCL3 | 12474.0 | nM | GI50 | C4349 | |
| TKC032619 | NCI-H226 | NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 | 20512.0 | nM | GI50 | C45662 | Orphanet_50251 |
| TKC032619 | SK-MEL-28 | SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 | 21086.0 | nM | GI50 | C3510 | |
| TKC032619 | HT-29 | HT 29; HT29 | 23550.0 | nM | GI50 | C4349 | |
| TKC032619 | RXF 393 | RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL | 12190.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC032619 | COLO 205 | Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 | 14454.0 | nM | GI50 | C4349 | |
| TKC032619 | HOP-18 | HOP 18; Hop 18; HOP18; Hop18; Hopkins-18 | 14894.0 | nM | GI50 | C4450 | |
| TKC032619 | SN12K1 | 16406.0 | nM | GI50 | C9385 | Orphanet_217071 |
| ID | Uniport | Pref_name | Gene name | value | unit | type |
|---|---|---|---|---|---|---|
| TKC032619 | P00352 | Retinal dehydrogenase 1 | ALDH1A1 | 19953 | nM | Potency |
| TKC032619 | P10636 | Microtubule-associated protein tau | MAPT | 2239 | nM | Potency |
| TKC032619 | P11473 | Vitamin D3 receptor | VDR | 31623 | nM | Potency |
| TKC032619 | Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | TDP1 | 2311 | nM | Potency |
| TKC032619 | P08684 | Cytochrome P450 3A4 | CYP3A4 | 25119 | nM | Potency |
| TKC032619 | O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | IDH1 | 16360 | nM | Potency |
| TKC032619 | P84022 | Mothers against decapentaplegic homolog 3 | SMAD3 | 12589 | nM | Potency |
| TKC032619 | Q03431 | Parathyroid hormone/parathyroid hormone-related peptide receptor | PTH1R | 35481 | nM | Potency |
| TKC032619 | Q16236 | Nuclear factor erythroid 2-related factor 2 | NFE2L2 | 3162 | nM | Potency |
| TKC032619 | Q99700 | Ataxin-2 | ATXN2 | 22387 | nM | Potency |
| TKC032619 | Q9UBT6 | DNA polymerase kappa | POLK | 1000 | nM | Potency |
| TKC032619 | O75496 | Geminin | GMNN | 4110 | nM | Potency |
| TKC032619 | O89049 | Thioredoxin reductase 1, cytoplasmic | Txnrd1 | 56234 | nM | Potency |
| TKC032619 | Q13148 | TAR DNA-binding protein 43 | TARDBP | 14125 | nM | Potency |
| TKC032619 | P05177 | Cytochrome P450 1A2 | CYP1A2 | 10000 | nM | AC50 |
| TKC032619 | P0DTD1 | Replicase polyprotein 1ab | rep | -1 | % | Inhibition |
| TKC032619 | P83916 | Chromobox protein homolog 1 | CBX1 | 79433 | nM | Potency |
| TKC032619 | Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | EHMT2 | 7943 | nM | Potency |
| TKC032619 | Q96QE3 | ATPase family AAA domain-containing protein 5 | ATAD5 | 25919 | nM | Potency |
| TKC032619 | Q01453 | Peripheral myelin protein 22 | PMP22 | 37933 | nM | Potency |
| TKC032619 | O00255 | Menin | MEN1 | 39811 | nM | Potency |
| TKC032619 | P02791 | Ferritin light chain | FTL | 50119 | nM | Potency |
| TKC032619 | P25779 | Cruzipain | 25119 | nM | Potency | |
| TKC032619 | P49798 | Regulator of G-protein signaling 4 | RGS4 | 37686 | nM | Potency |
| TKC032619 | P11021 | Endoplasmic reticulum chaperone BiP | HSPA5 | 14689 | nM | Potency |
| TKC032619 | P51450 | Nuclear receptor ROR-gamma | Rorc | 3981 | nM | Potency |
| TKC032619 | P02545 | Prelamin-A/C | LMNA | 5012 | nM | Potency |
| TKC032619 | P15917 | Lethal factor | lef | 6310 | nM | Potency |
| TKC032619 | O15118 | NPC intracellular cholesterol transporter 1 | NPC1 | 92000 | nM | Potency |
| TKC032619 | P51151 | Ras-related protein Rab-9A | RAB9A | 58048 | nM | Potency |
| TKC032619 | P42345 | Serine/threonine-protein kinase mTOR | MTOR | 2931 | nM | Potency |
| TKC032619 | P04637 | Cellular tumor antigen p53 | TP53 | 15849 | nM | Potency |
| TKC032619 | Q548M1 | 60 kDa chaperonin | groL | 70 | % | Inhibition |
| TKC032619 | P0A6C1 | Endonuclease 4 | nfo | 12589 | nM | Potency |
| TKC032619 | P42226 | Signal transducer and activator of transcription 6 | STAT6 | 7943 | nM | Potency |
| TKC032619 | Q99549 | M-phase phosphoprotein 8 | MPHOSPH8 | 891 | nM | Potency |
| Uniport ID | Uniport Name | ICD-11 |
|---|---|---|
| P10636 | TAU_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P10636 | TAU_HUMAN | Alzheimer disease [ICD-11: 8A20] |
| P10636 | TAU_HUMAN | Mild neurocognitive disorder [ICD-11: 6D71] |
| P10636 | TAU_HUMAN | Choreiform disorder [ICD-11: 8A01] |
| P10636 | TAU_HUMAN | Parkinsonism [ICD-11: 8A00] |
| P10636 | TAU_HUMAN | Central nervous system disease [ICD-11: 8A04-8D87] |
| P10636 | TAU_HUMAN | Neurodegenerative disorder [ICD-11: 8A20-8A23] |
| P11473 | VDR_HUMAN | Chronic kidney disease [ICD-11: GB61] |
| P11473 | VDR_HUMAN | Hair/hair growth developmental defect [ICD-11: LC30] |
| P11473 | VDR_HUMAN | Hyper-parathyroidism [ICD-11: 5A51] |
| P11473 | VDR_HUMAN | Hypo-parathyroidism [ICD-11: 5A50] |
| P11473 | VDR_HUMAN | Mineral deficiency [ICD-11: 5B5K] |
| P11473 | VDR_HUMAN | Psoriasis [ICD-11: EA90] |
| P11473 | VDR_HUMAN | Vitamin deficiency [ICD-11: 5B55-5B5F] |
| P11473 | VDR_HUMAN | Low bone mass disorder [ICD-11: FB83] |
| P11473 | VDR_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P11473 | VDR_HUMAN | Prostate cancer [ICD-11: 2C82] |
| P11473 | VDR_HUMAN | Prostate disease [ICD-11: GA91] |
| P11473 | VDR_HUMAN | Abnormal micturition [ICD-11: MF50] |
| P11473 | VDR_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P11473 | VDR_HUMAN | Postoperative inflammation [ICD-11: 1A00-CA43] |
| P11473 | VDR_HUMAN | Acne vulgaris [ICD-11: ED80] |
| P08684 | CP3A4_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P08684 | CP3A4_HUMAN | Atopic eczema [ICD-11: EA80] |
| P08684 | CP3A4_HUMAN | Anxiety disorder [ICD-11: 6B00-6B0Z] |
| O75874 | IDHC_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| O75874 | IDHC_HUMAN | Liver cancer [ICD-11: 2C12] |
| O75874 | IDHC_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| O75874 | IDHC_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| O75874 | IDHC_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| O75874 | IDHC_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P84022 | SMAD3_HUMAN | Herpes simplex infection [ICD-11: 1F00] |
| P84022 | SMAD3_HUMAN | Kidney fibrosis [ICD-11: GC01] |
| Q03431 | PTH1R_HUMAN | Low bone mass disorder [ICD-11: FB83] |
| Q03431 | PTH1R_HUMAN | Hypo-parathyroidism [ICD-11: 5A50] |
| Q16236 | NF2L2_HUMAN | Ataxic disorder [ICD-11: 8A03] |
| Q16236 | NF2L2_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| Q16236 | NF2L2_HUMAN | Glaucoma [ICD-11: 9C61] |
| Q16236 | NF2L2_HUMAN | Lung cancer [ICD-11: 2C25] |
| Q16236 | NF2L2_HUMAN | Macular degeneration [ICD-11: 9B75] |
| Q16236 | NF2L2_HUMAN | Melanoma [ICD-11: 2C30] |
| Q16236 | NF2L2_HUMAN | Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z] |
| Q16236 | NF2L2_HUMAN | Pulmonary hypertension [ICD-11: BB01] |
| Q16236 | NF2L2_HUMAN | Subarachnoid haemorrhage [ICD-11: 8B01] |
| Q16236 | NF2L2_HUMAN | Urinary system clinical sympton [ICD-11: MF8Y] |
| Q16236 | NF2L2_HUMAN | Non-alcoholic fatty liver disease [ICD-11: DB92] |
| Q16236 | NF2L2_HUMAN | Alpha-1-antitrypsin deficiency [ICD-11: 5C5A] |
| Q16236 | NF2L2_HUMAN | Motor neuron disease [ICD-11: 8B60] |
| Q16236 | NF2L2_HUMAN | Multiple sclerosis [ICD-11: 8A40] |
| Q13148 | TADBP_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| Q13148 | TADBP_HUMAN | Alzheimer disease [ICD-11: 8A20] |
| Q96KQ7 | EHMT2_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| Q96KQ7 | EHMT2_HUMAN | Postoperative inflammation [ICD-11: 1A00-CA43] |
| Q96KQ7 | EHMT2_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P25779 | CYSP_TRYCR | Parasitic worm infestation [ICD-11: 1F90] |
| P25779 | CYSP_TRYCR | Malaria [ICD-11: 1F40-1F45] |
| P11021 | BIP_HUMAN | Melanoma [ICD-11: 2C30] |
| P11021 | BIP_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P15917 | LEF_BACAN | Sepsis [ICD-11: 1G40-1G41] |
| P15917 | LEF_BACAN | Corneal disease [ICD-11: 9A76-9A78] |
| P51151 | RAB9A_HUMAN | Fungal infection [ICD-11: 1F29-1F2F] |
| P42345 | MTOR_HUMAN | Arteries/arterioles disorder [ICD-11: BD52] |
| P42345 | MTOR_HUMAN | Chronic myelomonocytic leukaemia [ICD-11: 2A40] |
| P42345 | MTOR_HUMAN | Hydrocephalus [ICD-11: 8D64] |
| P42345 | MTOR_HUMAN | Multiple myeloma [ICD-11: 2A83] |
| P42345 | MTOR_HUMAN | Renal cell carcinoma [ICD-11: 2C90] |
| P42345 | MTOR_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P42345 | MTOR_HUMAN | Transplant rejection [ICD-11: NE84] |
| P42345 | MTOR_HUMAN | Sarcoma [ICD-11: 2A60-2C35] |
| P42345 | MTOR_HUMAN | Bladder cancer [ICD-11: 2C94] |
| P42345 | MTOR_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| P42345 | MTOR_HUMAN | Endometrial cancer [ICD-11: 2C76] |
| P42345 | MTOR_HUMAN | Head and neck cancer [ICD-11: 2D42] |
| P42345 | MTOR_HUMAN | Liver cancer [ICD-11: 2C12] |
| P42345 | MTOR_HUMAN | Lung cancer [ICD-11: 2C25] |
| P42345 | MTOR_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| P42345 | MTOR_HUMAN | Malignant mesenchymal neoplasm [ICD-11: 2B5D-2B5Y] |
| P42345 | MTOR_HUMAN | Metastatic lymph node neoplasm [ICD-11: 2D60] |
| P42345 | MTOR_HUMAN | Pain [ICD-11: MG30-MG3Z] |
| P42345 | MTOR_HUMAN | Pancreatic cancer [ICD-11: 2C10] |
| P42345 | MTOR_HUMAN | Prostate cancer [ICD-11: 2C82] |
| P42345 | MTOR_HUMAN | Pulmonary hypertension [ICD-11: BB01] |
| P42345 | MTOR_HUMAN | Lymphangioleiomyomatosis [ICD-11: CB07] |
| P42345 | MTOR_HUMAN | Lymphoma [ICD-11: 2A80-2A86] |
| P42345 | MTOR_HUMAN | Pleural mesothelioma [ICD-11: 2C26] |
| P42345 | MTOR_HUMAN | Mature T-cell lymphoma [ICD-11: 2A90] |
| P42345 | MTOR_HUMAN | Postoperative inflammation [ICD-11: 1A00-CA43] |
| P42345 | MTOR_HUMAN | Ulcerative colitis [ICD-11: DD71] |
| P04637 | P53_HUMAN | Arterial occlusive disease [ICD-11: BD40] |
| P04637 | P53_HUMAN | Lip/oral cavity/pharynx neoplasm [ICD-11: 2B6E] |
| P04637 | P53_HUMAN | Metastatic liver/bile duct neoplasm [ICD-11: 2D80] |
| P04637 | P53_HUMAN | Transplant rejection [ICD-11: NE84] |
| P04637 | P53_HUMAN | Ovarian dysfunction [ICD-11: 5A80] |
| P04637 | P53_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P04637 | P53_HUMAN | Bladder cancer [ICD-11: 2C94] |
| P04637 | P53_HUMAN | Brain cancer [ICD-11: 2A00] |
| P04637 | P53_HUMAN | Colorectal cancer [ICD-11: 2B91] |
| P04637 | P53_HUMAN | Esophageal cancer [ICD-11: 2B70] |
| P04637 | P53_HUMAN | Head and neck cancer [ICD-11: 2D42] |
| P04637 | P53_HUMAN | Mature B-cell leukaemia [ICD-11: 2A82] |
| P04637 | P53_HUMAN | Myelodysplastic syndrome [ICD-11: 2A37] |
| P04637 | P53_HUMAN | Ovarian cancer [ICD-11: 2C73] |
| P04637 | P53_HUMAN | Pancreatic cancer [ICD-11: 2C10] |
| P04637 | P53_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P04637 | P53_HUMAN | Stomach cancer [ICD-11: 2B72] |
| P04637 | P53_HUMAN | Cervical cancer [ICD-11: 2C77] |
| P04637 | P53_HUMAN | Endometrial cancer [ICD-11: 2C76] |
| P04637 | P53_HUMAN | Fallopian tube cancer [ICD-11: 2C74] |
| P04637 | P53_HUMAN | Liposarcoma [ICD-11: 2B59] |
| P04637 | P53_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| P04637 | P53_HUMAN | Peritoneal cancer [ICD-11: 2C51] |
| P04637 | P53_HUMAN | Toxicity [ICD-11: N.A.] |
| P04637 | P53_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P04637 | P53_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| P04637 | P53_HUMAN | Kidney failure [ICD-11: GB60-GB6Z] |
| P04637 | P53_HUMAN | Hearing disorder [ICD-11: AB50-AB57] |