Basic Information

Terpenoid ID TKC005454
Cell line 0
Protein target 65
DiseaseNCIT 0
ORDO 0
ICD 126

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC005454 AGS 10200.0 nM IC50 C4004
TKC005454 PBMC 37400.0 nM IC50
TKC005454 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 9.0 uM CD50 C105555
TKC005454 HepG2 10000.0 nM Potency C3728 Orphanet_449
TKC005454 HeLa HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri 17.0 uM CD50 C27677
TKC005454 MIA PaCa-2 MIA-PaCa-2; MIA-PACA-2; MIA-Pa-Ca-2; MIA Paca2; MIA PaCa2; MiaPaCa-2; MIAPACA-2; MiaPaca.2; MiaPaCa2; Miapaca2; MIAPaCa2; MIAPACA2; Mia PACA 2; MIAPaCa-2; PaCa2; MiaPaCa 5800.0 nM IC50 C9120
TKC005454 Vero VERO; VeroCCL81; Vero 81; Vero-81; Verda reno 33380.0 nM CC50
TKC005454 MDA-N MDAN 1611.0 nM GI50 C3802
TKC005454 SN12C SN-12C 4365.0 nM GI50 C9385 Orphanet_217071
TKC005454 NCI-H23 NCI.H23; NCI H23; H-23; H23; NCIH23 1549.0 nM GI50 C3512
TKC005454 ACHN 3597.0 nM GI50 C6975 Orphanet_319298
TKC005454 UO-31 UO.31; UO31; U031 4699.0 nM GI50 C9385 Orphanet_217071
TKC005454 HOP-92 HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 40832.0 nM GI50 C2926
TKC005454 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 2388.0 nM GI50 C9154 Orphanet_519
TKC005454 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 1352.0 nM GI50 C4863
TKC005454 SF-539 SF-539; SF-539 BT; SF.539; SF 539 3350.0 nM GI50 C3796 Orphanet_251576
TKC005454 Malme-3M MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer 305.0 nM GI50 C3224
TKC005454 SK-MEL-5 SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel 382.0 nM GI50 C3510
TKC005454 K562 K562; K.562; K 562; KO; GM05372; GM05372E 3606.0 nM GI50 C9110 Orphanet_521
TKC005454 A498 A498 18323.0 nM GI50 C9385 Orphanet_217071
TKC005454 MOLT-4 Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D 4236.0 nM GI50 C9142 Orphanet_99861
TKC005454 HOP-62 HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 3681.0 nM GI50 C3512
TKC005454 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 1995.0 nM GI50 C60781 Orphanet_94
TKC005454 NCI/ADR-RES NCI/ADR-RES; NCI.ADR.RES; NCIADR.RES; NCI/ADRRES; NCIADRRES; ADR-RES; MCF-7/ADR; MCF-7/ADR-RES; MCF-7/AdrR; MCF-7/Adr; MCF-7/adr; MCF-7ADR; MCF7-ADR; MCF7ADR; OVCAR-8/ADR; OVCAR8/ADR 2786.0 nM GI50 C105555
TKC005454 OVCAR-5 OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 16069.0 nM GI50 C105555
TKC005454 OVCAR-8 OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 2576.0 nM GI50 C105555
TKC005454 SNB-19 SNB.19; SNB19; Surgical Neurology Branch-19 2518.0 nM GI50 C60781 Orphanet_94
TKC005454 TK-10 TK.10; TK 10; TK10 8185.0 nM GI50 C4033 Orphanet_319276
TKC005454 SR SR-786; SR786 3420.0 nM GI50 C37193 Orphanet_300895
TKC005454 SW-620 SW-620; SW 620; SW.620 1730.0 nM GI50 C4349
TKC005454 NCI-H522 NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 2009.0 nM GI50 C3512
TKC005454 KM12 KM-12; KM.12 2193.0 nM GI50 C4910
TKC005454 M14 M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 1033.0 nM GI50 C3802
TKC005454 NCI-H322M NCI.H322M; H322M; H-322M; H-322m 1644.0 nM GI50 C2923
TKC005454 RPMI-8226 RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson 3311.0 nM GI50 C3242 Orphanet_29073
TKC005454 OVCAR-4 OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 12190.0 nM GI50 C105555
TKC005454 LOX IMVI LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX 2518.0 nM GI50 C3802
TKC005454 BT-549 BT 549; BT.549; BT549 2109.0 nM GI50 C4194
TKC005454 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 4246.0 nM GI50 C3224
TKC005454 A549 1050.0 nM GI50 C3512
TKC005454 SNB-75 SNB.75; SNB75; Surgical Neurology Branch-75 881.0 nM GI50 C3058 Orphanet_360
TKC005454 HCC 2998 HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 2483.0 nM GI50 C4349
TKC005454 HCT-15 HCT-15; HCT.15; HCT15 1941.0 nM GI50 C4349
TKC005454 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 2965.0 nM GI50 C4910
TKC005454 SF-268 SF-268; SF.268; SF 268 1901.0 nM GI50 C60781 Orphanet_94
TKC005454 EKVX 4624.0 nM GI50 C3512
TKC005454 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 11614.0 nM GI50 C7978
TKC005454 PC-3 PC3; PC.3 4932.0 nM GI50 C4863
TKC005454 T47D 9462.0 nM GI50 C4194
TKC005454 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 1633.0 nM GI50 C4450
TKC005454 UACC-62 UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 2032.0 nM GI50 C3224
TKC005454 MDA-MB-435 MDA-MB435; MDAMB435; MDA.MB.435; MDA-435; MDA 435; MDA435; MD Anderson-Metastatic Breast-435 1416.0 nM GI50 C3802
TKC005454 CAKI-1 CAL 1; Centre Antoine Lacassagne-1 8222.0 nM GI50 C3224
TKC005454 SF-295 SF-295; SF.295; SF 295 1679.0 nM GI50 C3058 Orphanet_360
TKC005454 IGROV-1 Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P 2710.0 nM GI50 C7979 Orphanet_454723
TKC005454 Hs-578T HS 578T; Hs-578T; HS-578T; Hs_578t; Hs-578-T; HS-578-T; Hs 578.T; HS578T; Hs578T; Hs578t; HS0578T; 578T; HS578; Hs578; Homo sapiens No. 578, tumor cells 2291.0 nM GI50 C4194
TKC005454 UACC-257 UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 1954.0 nM GI50 C3224
TKC005454 786-0 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT 3420.0 nM GI50 C9385 Orphanet_217071
TKC005454 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 4305.0 nM GI50 C7953 Orphanet_99861
TKC005454 NCI-H226 NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 3243.0 nM GI50 C45662 Orphanet_50251
TKC005454 HT-29 HT 29; HT29 2183.0 nM GI50 C4349
TKC005454 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 3192.0 nM GI50 C3510
TKC005454 RXF 393 RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL 6295.0 nM GI50 C9385 Orphanet_217071
TKC005454 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 1148.0 nM GI50 C4349

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC005454 P00352 Retinal dehydrogenase 1 ALDH1A1 10000 nM Potency
TKC005454 P10636 Microtubule-associated protein tau MAPT 3548 nM Potency
TKC005454 P11473 Vitamin D3 receptor VDR 7080 nM Potency
TKC005454 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 12995 nM Potency
TKC005454 P18031 Tyrosine-protein phosphatase non-receptor type 1 PTPN1 33500 nM IC50
TKC005454 P08575 Receptor-type tyrosine-protein phosphatase C PTPRC 41400 nM IC50
TKC005454 P17706 Tyrosine-protein phosphatase non-receptor type 2 PTPN2 55700 nM IC50
TKC005454 P07943 Aldo-keto reductase family 1 member B1 Akr1b1 4786 nM IC50
TKC005454 P07943 Aldo-keto reductase family 1 member B1 Akr1b1 4786 nM IC50
TKC005454 P08684 Cytochrome P450 3A4 CYP3A4 15849 nM Potency
TKC005454 P22303 Acetylcholinesterase ACHE >6410 nM Ki
TKC005454 P23141 Liver carboxylesterase 1 CES1 544 nM Ki
TKC005454 Q72874 Protease pol 69600 nM IC50
TKC005454 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 20596 nM Potency
TKC005454 O95398 Rap guanine nucleotide exchange factor 3 RAPGEF3 44668 nM Potency
TKC005454 P43220 Glucagon-like peptide 1 receptor GLP1R 28184 nM Potency
TKC005454 P53350 Serine/threonine-protein kinase PLK1 PLK1 26680 nM Potency
TKC005454 P84022 Mothers against decapentaplegic homolog 3 SMAD3 4467 nM Potency
TKC005454 Q14191 Werner syndrome ATP-dependent helicase WRN 56234 nM Potency
TKC005454 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 29093 nM Potency
TKC005454 O75164 Lysine-specific demethylase 4A KDM4A 31623 nM Potency
TKC005454 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 39811 nM Potency
TKC005454 Q962Y6 Thioredoxin glutathione reductase TGR 3981 nM Potency
TKC005454 Q9UBT6 DNA polymerase kappa POLK 19953 nM Potency
TKC005454 Q9UNA4 DNA polymerase iota POLI 22387 nM Potency
TKC005454 P08183 ATP-dependent translocase ABCB1 ABCB1 50 % Inhibition
TKC005454 O75496 Geminin GMNN 4110 nM Potency
TKC005454 O89049 Thioredoxin reductase 1, cytoplasmic Txnrd1 28184 nM Potency
TKC005454 O94782 Ubiquitin carboxyl-terminal hydrolase 1 USP1 79433 nM Potency
TKC005454 P39748 Flap endonuclease 1 FEN1 14125 nM Potency
TKC005454 P40763 Signal transducer and activator of transcription 3 STAT3 4600 nM IC50
TKC005454 O42275 Acetylcholinesterase ache 3 % Inhibition
TKC005454 P0DTD1 Replicase polyprotein 1ab rep -10 % Inhibition
TKC005454 P81908 Cholinesterase BCHE 12 % Inhibition
TKC005454 P83916 Chromobox protein homolog 1 CBX1 28184 nM Potency
TKC005454 P00784 Papain 89800 nM IC50
TKC005454 P0C6U8 Replicase polyprotein 1a 1a 800 nM IC50
TKC005454 Q01196 Runt-related transcription factor 1 RUNX1 12589 nM Potency
TKC005454 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 EHMT2 7080 nM Potency
TKC005454 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 16354 nM Potency
TKC005454 P08659 Luciferin 4-monooxygenase 21331 nM Potency
TKC005454 P54132 Bloom syndrome protein BLM 39811 nM Potency
TKC005454 Q6W5P4 Neuropeptide S receptor NPSR1 25119 nM Potency
TKC005454 B2RXH2 Lysine-specific demethylase 4E KDM4E 35481 nM Potency
TKC005454 O00255 Menin MEN1 17783 nM Potency
TKC005454 O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B ALOX15B 25119 nM Potency
TKC005454 O97447 Putative fructose-1,6-bisphosphate aldolase fba 1581 nM Potency
TKC005454 P02791 Ferritin light chain FTL 35481 nM Potency
TKC005454 P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] HPGD 19953 nM Potency
TKC005454 P25779 Cruzipain 39811 nM Potency
TKC005454 P46063 ATP-dependent DNA helicase Q1 RECQL 12589 nM Potency
TKC005454 P55210 Caspase-7 CASP7 25119 nM Potency
TKC005454 Q92830 Histone acetyltransferase KAT2A KAT2A 28184 nM Potency
TKC005454 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 25119 nM Potency
TKC005454 Q9F4F7 4'-phosphopantetheinyl transferase ffp ffp 19953 nM Potency
TKC005454 O00748 Cocaine esterase CES2 141 nM Ki
TKC005454 O14746 Telomerase reverse transcriptase TERT 75 % Inhibition
TKC005454 P06746 DNA polymerase beta POLB 22387 nM Potency
TKC005454 P10520 Streptokinase A ska 3953 nM EC50
TKC005454 P10586 Receptor-type tyrosine-protein phosphatase F PTPRF 36900 nM IC50
TKC005454 P10828 Thyroid hormone receptor beta THRB 50119 nM Potency
TKC005454 P29350 Tyrosine-protein phosphatase non-receptor type 6 PTPN6 39500 nM IC50
TKC005454 P29990 Genome polyprotein 90060 nM IC50
TKC005454 P43378 Tyrosine-protein phosphatase non-receptor type 9 PTPN9 59400 nM IC50
TKC005454 P49798 Regulator of G-protein signaling 4 RGS4 56234 nM Potency
TKC005454 Q03164 Histone-lysine N-methyltransferase 2A KMT2A 31623 nM Potency
TKC005454 Q06124 Tyrosine-protein phosphatase non-receptor type 11 PTPN11 22500 nM IC50
TKC005454 Q16665 Hypoxia-inducible factor 1-alpha HIF1A 1360 nM IC50
TKC005454 Q9NR56 Muscleblind-like protein 1 MBNL1 44668 nM Potency
TKC005454 Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B BAZ2B 14125 nM Potency
TKC005454 Q9Y253 DNA polymerase eta POLH 35481 nM Potency
TKC005454 Q9Y468 Lethal(3)malignant brain tumor-like protein 1 L3MBTL1 17783 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P11473 VDR_HUMAN Chronic kidney disease [ICD-11: GB61]
P11473 VDR_HUMAN Hair/hair growth developmental defect [ICD-11: LC30]
P11473 VDR_HUMAN Hyper-parathyroidism [ICD-11: 5A51]
P11473 VDR_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P11473 VDR_HUMAN Mineral deficiency [ICD-11: 5B5K]
P11473 VDR_HUMAN Psoriasis [ICD-11: EA90]
P11473 VDR_HUMAN Vitamin deficiency [ICD-11: 5B55-5B5F]
P11473 VDR_HUMAN Low bone mass disorder [ICD-11: FB83]
P11473 VDR_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11473 VDR_HUMAN Prostate cancer [ICD-11: 2C82]
P11473 VDR_HUMAN Prostate disease [ICD-11: GA91]
P11473 VDR_HUMAN Abnormal micturition [ICD-11: MF50]
P11473 VDR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11473 VDR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P11473 VDR_HUMAN Acne vulgaris [ICD-11: ED80]
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P18031 PTN1_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P18031 PTN1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P18031 PTN1_HUMAN Obesity [ICD-11: 5B80-5B81]
P18031 PTN1_HUMAN Ophthalmic devices/implants/grafts injury [ICD-11: PK97]
P18031 PTN1_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P18031 PTN1_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
P18031 PTN1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P08575 PTPRC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P08575 PTPRC_HUMAN Transplanted organ/tissue [ICD-11: QB63]
P08575 PTPRC_HUMAN Leukaemia [ICD-11: 2A60-2B33]
P08575 PTPRC_HUMAN Diffuse large B-cell lymphoma [ICD-11: 2A81]
P08575 PTPRC_HUMAN Lymphoma [ICD-11: 2A80-2A86]
P08575 PTPRC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P08575 PTPRC_HUMAN Transplant rejection [ICD-11: NE84]
P08575 PTPRC_HUMAN Pain [ICD-11: MG30-MG3Z]
P17706 PTN2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
P22303 ACES_HUMAN Alzheimer disease [ICD-11: 8A20]
P22303 ACES_HUMAN Glaucoma [ICD-11: 9C61]
P22303 ACES_HUMAN Myasthenia gravis [ICD-11: 8C6Y]
P22303 ACES_HUMAN Oesophageal/gastroduodenal disorder [ICD-11: DD90]
P22303 ACES_HUMAN Pediculosis [ICD-11: 1G00]
P22303 ACES_HUMAN Unspecific substance harmful effect [ICD-11: NE6Z]
P22303 ACES_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P22303 ACES_HUMAN Parasitic worm infestation [ICD-11: 1F90]
P22303 ACES_HUMAN Dementia [ICD-11: 6D80-6D8Z]
P22303 ACES_HUMAN Pain [ICD-11: MG30-MG3Z]
P22303 ACES_HUMAN Parkinsonism [ICD-11: 8A00]
P22303 ACES_HUMAN Substance abuse [ICD-11: 6C40]
P22303 ACES_HUMAN Lips/oral mucosa miscellaneous disorder [ICD-11: DA02]
P22303 ACES_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P22303 ACES_HUMAN Urinary system disease [ICD-11: GC2Z]
P22303 ACES_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P23141 EST1_HUMAN Peroxisomal disease [ICD-11: 5C57]
P23141 EST1_HUMAN Synthesis disorder [ICD-11: 5C52-5C59]
P23141 EST1_HUMAN Arterial occlusive disease [ICD-11: BD40]
P23141 EST1_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P23141 EST1_HUMAN Mature B-cell lymphoma [ICD-11: 2A85]
P23141 EST1_HUMAN Chronic arterial occlusive disease [ICD-11: BD4Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O95398 RPGF3_HUMAN Epidermal dysplasias [ICD-11: EK90]
P43220 GLP1R_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P43220 GLP1R_HUMAN Obesity [ICD-11: 5B80-5B81]
P43220 GLP1R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P43220 GLP1R_HUMAN Type-1/2 diabete [ICD-11: 5A10-5A11]
P43220 GLP1R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P43220 GLP1R_HUMAN Diabetes mellitus [ICD-11: 5A10]
P43220 GLP1R_HUMAN Dyspepsia [ICD-11: MD92]
P43220 GLP1R_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P43220 GLP1R_HUMAN Intracranial injury [ICD-11: NA07]
P43220 GLP1R_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
P53350 PLK1_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P53350 PLK1_HUMAN Myelodysplastic syndrome [ICD-11: 2A37]
P53350 PLK1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P53350 PLK1_HUMAN Prostate cancer [ICD-11: 2C82]
P53350 PLK1_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P53350 PLK1_HUMAN Pancreatic cancer [ICD-11: 2C10]
P53350 PLK1_HUMAN Lymphoma [ICD-11: 2A80-2A86]
P53350 PLK1_HUMAN Nasopharyngeal cancer [ICD-11: 2B6B]
P53350 PLK1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q14191 WRN_HUMAN Mature T-cell lymphoma [ICD-11: 2A90]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]
P08183 MDR1_HUMAN Lung cancer [ICD-11: 2C25]
P08183 MDR1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08183 MDR1_HUMAN Bacterial infection [ICD-11: 1A00-1C4Z]
P08183 MDR1_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P08183 MDR1_HUMAN Adrenal cancer [ICD-11: 2D11]
P08183 MDR1_HUMAN Ovarian cancer [ICD-11: 2C73]
O94782 UBP1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P40763 STAT3_HUMAN Psoriasis [ICD-11: EA90]
P40763 STAT3_HUMAN Brain cancer [ICD-11: 2A00]
P40763 STAT3_HUMAN Colorectal cancer [ICD-11: 2B91]
P40763 STAT3_HUMAN Liver cancer [ICD-11: 2C12]
P40763 STAT3_HUMAN Malignant digestive organ neoplasm [ICD-11: 2C11]
P40763 STAT3_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P40763 STAT3_HUMAN Pancreatic cancer [ICD-11: 2C10]
P40763 STAT3_HUMAN Respiratory infection [ICD-11: CA07-CA4Z]
P40763 STAT3_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P40763 STAT3_HUMAN Immune system disease [ICD-11: 4A01-4B41]
P40763 STAT3_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P40763 STAT3_HUMAN Mature B-cell leukaemia [ICD-11: 2A82]
P40763 STAT3_HUMAN Multiple myeloma [ICD-11: 2A83]
P40763 STAT3_HUMAN Mycosis fungoides [ICD-11: 2B01]
P40763 STAT3_HUMAN Ulcerative colitis [ICD-11: DD71]
P40763 STAT3_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q96KQ7 EHMT2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96KQ7 EHMT2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q96KQ7 EHMT2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P25779 CYSP_TRYCR Parasitic worm infestation [ICD-11: 1F90]
P25779 CYSP_TRYCR Malaria [ICD-11: 1F40-1F45]
P55210 CASP7_HUMAN Cystic fibrosis [ICD-11: CA25]
O14746 TERT_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
O14746 TERT_HUMAN Colorectal cancer [ICD-11: 2B91]
O14746 TERT_HUMAN Liver cancer [ICD-11: 2C12]
O14746 TERT_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O14746 TERT_HUMAN Pancreatic cancer [ICD-11: 2C10]
O14746 TERT_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
O14746 TERT_HUMAN Lung cancer [ICD-11: 2C25]
O14746 TERT_HUMAN Multiple myeloma [ICD-11: 2A83]
O14746 TERT_HUMAN Myelodysplastic syndrome [ICD-11: 2A37]
O14746 TERT_HUMAN Myeloproliferative neoplasm [ICD-11: 2A20]
O14746 TERT_HUMAN Thrombocytosis [ICD-11: 3B63]
O14746 TERT_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O14746 TERT_HUMAN Melanoma [ICD-11: 2C30]
O14746 TERT_HUMAN Ovarian cancer [ICD-11: 2C73]
O14746 TERT_HUMAN Glaucoma [ICD-11: 9C61]
O14746 TERT_HUMAN Head and neck cancer [ICD-11: 2D42]
O14746 TERT_HUMAN Liver cancer [ICD-11: 2C12]
O14746 TERT_HUMAN Brain cancer [ICD-11: 2A00]
O14746 TERT_HUMAN Prostate cancer [ICD-11: 2C82]
O14746 TERT_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P06746 DPOLB_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P10828 THB_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]
P10828 THB_HUMAN Hypo-thyroidism [ICD-11: 5A00]
P10828 THB_HUMAN Inborn lipid metabolism error [ICD-11: 5C52]
P10828 THB_HUMAN Skin postprocedural disorder [ICD-11: EL8Y]
P10828 THB_HUMAN Thyrotoxicosis [ICD-11: 5A02]
Q06124 PTN11_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q16665 HIF1A_HUMAN Adrenomedullary hyperfunction [ICD-11: 5A75]
Q16665 HIF1A_HUMAN Brain cancer [ICD-11: 2A00]
Q16665 HIF1A_HUMAN Lymphoma [ICD-11: 2A80-2A86]
Q16665 HIF1A_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q16665 HIF1A_HUMAN Pulmonary hypertension [ICD-11: BB01]