Basic Information

Terpenoid ID TKC106426
Chirality TKC013755
Cell line 0
Protein target 20
DiseaseNCIT 0
ORDO 0
ICD 45

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC106426 P00352 Retinal dehydrogenase 1 ALDH1A1 8913 nM Potency
TKC106426 P10636 Microtubule-associated protein tau MAPT 31623 nM Potency
TKC106426 P11473 Vitamin D3 receptor VDR 14125 nM Potency
TKC106426 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 52 nM Potency
TKC106426 P08684 Cytochrome P450 3A4 CYP3A4 12589 nM AC50
TKC106426 Q99700 Ataxin-2 ATXN2 6310 nM Potency
TKC106426 P19838 Nuclear factor NF-kappa-B p105 subunit NFKB1 3981 nM Potency
TKC106426 O94782 Ubiquitin carboxyl-terminal hydrolase 1 USP1 7943 nM Potency
TKC106426 P05177 Cytochrome P450 1A2 CYP1A2 19953 nM AC50
TKC106426 P10635 Cytochrome P450 2D6 CYP2D6 1995 nM AC50
TKC106426 P11712 Cytochrome P450 2C9 CYP2C9 1259 nM Potency
TKC106426 P33261 Cytochrome P450 2C19 CYP2C19 5012 nM AC50
TKC106426 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 EHMT2 8913 nM Potency
TKC106426 P25779 Cruzipain 39811 nM Potency
TKC106426 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 31623 nM Potency
TKC106426 Q16665 Hypoxia-inducible factor 1-alpha HIF1A 1000 nM Potency
TKC106426 P16050 Polyunsaturated fatty acid lipoxygenase ALOX15 ALOX15 3981 nM Potency
TKC106426 P51450 Nuclear receptor ROR-gamma Rorc 1259 nM Potency
TKC106426 P02545 Prelamin-A/C LMNA 282 nM Potency
TKC106426 P15917 Lethal factor lef 12589 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P11473 VDR_HUMAN Chronic kidney disease [ICD-11: GB61]
P11473 VDR_HUMAN Hair/hair growth developmental defect [ICD-11: LC30]
P11473 VDR_HUMAN Hyper-parathyroidism [ICD-11: 5A51]
P11473 VDR_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P11473 VDR_HUMAN Mineral deficiency [ICD-11: 5B5K]
P11473 VDR_HUMAN Psoriasis [ICD-11: EA90]
P11473 VDR_HUMAN Vitamin deficiency [ICD-11: 5B55-5B5F]
P11473 VDR_HUMAN Low bone mass disorder [ICD-11: FB83]
P11473 VDR_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11473 VDR_HUMAN Prostate cancer [ICD-11: 2C82]
P11473 VDR_HUMAN Prostate disease [ICD-11: GA91]
P11473 VDR_HUMAN Abnormal micturition [ICD-11: MF50]
P11473 VDR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11473 VDR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P11473 VDR_HUMAN Acne vulgaris [ICD-11: ED80]
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
P19838 NFKB1_HUMAN Muscular dystrophy [ICD-11: 8C70]
P19838 NFKB1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P19838 NFKB1_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
O94782 UBP1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P10635 CP2D6_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
P10635 CP2D6_HUMAN Malaria [ICD-11: 1F40-1F45]
P10635 CP2D6_HUMAN Migraine [ICD-11: 8A80]
P11712 CP2C9_HUMAN Bacterial infection [ICD-11: 1A00-1C4Z]
Q96KQ7 EHMT2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96KQ7 EHMT2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q96KQ7 EHMT2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P25779 CYSP_TRYCR Parasitic worm infestation [ICD-11: 1F90]
P25779 CYSP_TRYCR Malaria [ICD-11: 1F40-1F45]
Q16665 HIF1A_HUMAN Adrenomedullary hyperfunction [ICD-11: 5A75]
Q16665 HIF1A_HUMAN Brain cancer [ICD-11: 2A00]
Q16665 HIF1A_HUMAN Lymphoma [ICD-11: 2A80-2A86]
Q16665 HIF1A_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q16665 HIF1A_HUMAN Pulmonary hypertension [ICD-11: BB01]
P15917 LEF_BACAN Sepsis [ICD-11: 1G40-1G41]
P15917 LEF_BACAN Corneal disease [ICD-11: 9A76-9A78]