Basic Information

Terpenoid ID TKC073833
Cell line 0
Protein target 23
DiseaseNCIT 0
ORDO 0
ICD 58

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC073833 Vero VERO; VeroCCL81; Vero 81; Vero-81; Verda reno 14940.0 nM CC50
TKC073833 HepG2 35481.0 nM Potency C3728 Orphanet_449
TKC073833 HEK293 20596.0 nM Potency

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC073833 P11473 Vitamin D3 receptor VDR 56234 nM Potency
TKC073833 Q16637 Survival motor neuron protein SMN1,SMN2 5012 nM Potency
TKC073833 Q16637 Survival motor neuron protein SMN1,SMN2 5012 nM Potency
TKC073833 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 3264 nM Potency
TKC073833 P43220 Glucagon-like peptide 1 receptor GLP1R 10000 nM Potency
TKC073833 P84022 Mothers against decapentaplegic homolog 3 SMAD3 12589 nM Potency
TKC073833 Q06710 Paired box protein Pax-8 PAX8 3370 nM AC50
TKC073833 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 14581 nM Potency
TKC073833 Q99700 Ataxin-2 ATXN2 17783 nM Potency
TKC073833 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 3 nM Potency
TKC073833 Q962Y6 Thioredoxin glutathione reductase TGR 10000 nM Potency
TKC073833 Q9UNA4 DNA polymerase iota POLI 22387 nM Potency
TKC073833 O75496 Geminin GMNN 2593 nM Potency
TKC073833 O89049 Thioredoxin reductase 1, cytoplasmic Txnrd1 15849 nM Potency
TKC073833 Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G APOBEC3G 3548 nM Potency
TKC073833 P83916 Chromobox protein homolog 1 CBX1 100000 nM Potency
TKC073833 P00811 Beta-lactamase ampC 316 nM Potency
TKC073833 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 16360 nM Potency
TKC073833 Q9F4F7 4'-phosphopantetheinyl transferase ffp ffp 44668 nM Potency
TKC073833 P51450 Nuclear receptor ROR-gamma Rorc 2512 nM Potency
TKC073833 P02545 Prelamin-A/C LMNA 10000 nM Potency
TKC073833 P42858 Huntingtin HTT 3162 nM Potency
TKC073833 P51151 Ras-related protein Rab-9A RAB9A 3548 nM Potency
TKC073833 P00749 Urokinase-type plasminogen activator PLAU 58479 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P11473 VDR_HUMAN Chronic kidney disease [ICD-11: GB61]
P11473 VDR_HUMAN Hair/hair growth developmental defect [ICD-11: LC30]
P11473 VDR_HUMAN Hyper-parathyroidism [ICD-11: 5A51]
P11473 VDR_HUMAN Hypo-parathyroidism [ICD-11: 5A50]
P11473 VDR_HUMAN Mineral deficiency [ICD-11: 5B5K]
P11473 VDR_HUMAN Psoriasis [ICD-11: EA90]
P11473 VDR_HUMAN Vitamin deficiency [ICD-11: 5B55-5B5F]
P11473 VDR_HUMAN Low bone mass disorder [ICD-11: FB83]
P11473 VDR_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11473 VDR_HUMAN Prostate cancer [ICD-11: 2C82]
P11473 VDR_HUMAN Prostate disease [ICD-11: GA91]
P11473 VDR_HUMAN Abnormal micturition [ICD-11: MF50]
P11473 VDR_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11473 VDR_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P11473 VDR_HUMAN Acne vulgaris [ICD-11: ED80]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
P43220 GLP1R_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P43220 GLP1R_HUMAN Obesity [ICD-11: 5B80-5B81]
P43220 GLP1R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P43220 GLP1R_HUMAN Type-1/2 diabete [ICD-11: 5A10-5A11]
P43220 GLP1R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P43220 GLP1R_HUMAN Diabetes mellitus [ICD-11: 5A10]
P43220 GLP1R_HUMAN Dyspepsia [ICD-11: MD92]
P43220 GLP1R_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P43220 GLP1R_HUMAN Intracranial injury [ICD-11: NA07]
P43220 GLP1R_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]
P42858 HD_HUMAN Choreiform disorder [ICD-11: 8A01]
P51151 RAB9A_HUMAN Fungal infection [ICD-11: 1F29-1F2F]
P00749 UROK_HUMAN Inherited coagulation factor deficiency [ICD-11: 3B14]
P00749 UROK_HUMAN Myocardial infarction [ICD-11: BA41-BA43]
P00749 UROK_HUMAN Thrombosis [ICD-11: DB61-GB90]
P00749 UROK_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P00749 UROK_HUMAN Cerebral ischaemia [ICD-11: 8B1Z]
P00749 UROK_HUMAN Cardiomegaly [ICD-11: BC45]
P00749 UROK_HUMAN Ischaemic heart disease [ICD-11: BA6Z]
P00749 UROK_HUMAN Unspecific body region injury [ICD-11: ND56]
P00749 UROK_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]