Basic Information

Terpenoid ID TKC205806
Cell line 0
Protein target 18
DiseaseNCIT 0
ORDO 0
ICD 61

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC205806 P08684 Cytochrome P450 3A4 CYP3A4 10000 nM Potency
TKC205806 O94782 Ubiquitin carboxyl-terminal hydrolase 1 USP1 31623 nM Potency
TKC205806 P05177 Cytochrome P450 1A2 CYP1A2 3981 nM AC50
TKC205806 P08913 Alpha-2A adrenergic receptor ADRA2A 8 nM Ki
TKC205806 P10635 Cytochrome P450 2D6 CYP2D6 2 nM AC50
TKC205806 P10635 Cytochrome P450 2D6 CYP2D6 4.6 nM Ki
TKC205806 P11712 Cytochrome P450 2C9 CYP2C9 10000 nM Potency
TKC205806 P18089 Alpha-2B adrenergic receptor ADRA2B 15 nM Ki
TKC205806 P18825 Alpha-2C adrenergic receptor ADRA2C 5 nM Ki
TKC205806 P33261 Cytochrome P450 2C19 CYP2C19 12589 nM AC50
TKC205806 Q9WKE8 Reverse transcriptase reverse transcriptase >200 ug.mL-1 IC50
TKC205806 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 EHMT2 7943 nM Potency
TKC205806 B2RXH2 Lysine-specific demethylase 4E KDM4E 12589 nM Potency
TKC205806 O00255 Menin MEN1 14125 nM Potency
TKC205806 O97447 Putative fructose-1,6-bisphosphate aldolase fba 5610 nM Potency
TKC205806 Q92830 Histone acetyltransferase KAT2A KAT2A 15849 nM Potency
TKC205806 Q16665 Hypoxia-inducible factor 1-alpha HIF1A 5012 nM Potency
TKC205806 P22002 Voltage-dependent L-type calcium channel subunit alpha-1C Cacna1c 289 nM Ki
TKC205806 P02545 Prelamin-A/C LMNA 7 nM Potency
TKC205806 P68871 Hemoglobin subunit beta HBB 12589 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
O94782 UBP1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08913 ADA2A_HUMAN Attention deficit hyperactivity disorder [ICD-11: 6A05]
P08913 ADA2A_HUMAN Opioid use disorder [ICD-11: 6C43]
P08913 ADA2A_HUMAN Substance abuse [ICD-11: 6C40]
P08913 ADA2A_HUMAN Pain [ICD-11: MG30-MG3Z]
P08913 ADA2A_HUMAN Depression [ICD-11: 6A70-6A7Z]
P08913 ADA2A_HUMAN Sexual dysfunction [ICD-11: HA00-HA01]
P08913 ADA2A_HUMAN Genetic cardiac arrhythmia [ICD-11: BC65]
P08913 ADA2A_HUMAN Dementia [ICD-11: 6D80-6D8Z]
P08913 ADA2A_HUMAN Obesity [ICD-11: 5B80-5B81]
P10635 CP2D6_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
P10635 CP2D6_HUMAN Malaria [ICD-11: 1F40-1F45]
P10635 CP2D6_HUMAN Migraine [ICD-11: 8A80]
P10635 CP2D6_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
P10635 CP2D6_HUMAN Malaria [ICD-11: 1F40-1F45]
P10635 CP2D6_HUMAN Migraine [ICD-11: 8A80]
P11712 CP2C9_HUMAN Bacterial infection [ICD-11: 1A00-1C4Z]
P18089 ADA2B_HUMAN Substance abuse [ICD-11: 6C40]
P18089 ADA2B_HUMAN General pain disorder [ICD-11: 8E43]
P18089 ADA2B_HUMAN Pain [ICD-11: MG30-MG3Z]
P18089 ADA2B_HUMAN Hypertension [ICD-11: BA00-BA04]
P18089 ADA2B_HUMAN Genetic cardiac arrhythmia [ICD-11: BC65]
P18825 ADA2C_HUMAN Glaucoma [ICD-11: 9C61]
P18825 ADA2C_HUMAN Herpes simplex infection [ICD-11: 1F00]
P18825 ADA2C_HUMAN Hypertension [ICD-11: BA00-BA04]
P18825 ADA2C_HUMAN Hypotension [ICD-11: BA20-BA21]
P18825 ADA2C_HUMAN Obesity [ICD-11: 5B80-5B81]
P18825 ADA2C_HUMAN Substance abuse [ICD-11: 6C40]
P18825 ADA2C_HUMAN Vasomotor/allergic rhinitis [ICD-11: CA08]
P18825 ADA2C_HUMAN Chronic pain [ICD-11: MG30]
P18825 ADA2C_HUMAN Dissociative neurological symptom disorder [ICD-11: 6B60]
P18825 ADA2C_HUMAN Post-traumatic stress disorder [ICD-11: 6B40]
P18825 ADA2C_HUMAN Alzheimer disease [ICD-11: 8A20]
P18825 ADA2C_HUMAN Chronic arterial occlusive disease [ICD-11: BD4Z]
P18825 ADA2C_HUMAN Chronic kidney disease [ICD-11: GB61]
P18825 ADA2C_HUMAN General pain disorder [ICD-11: 8E43]
P18825 ADA2C_HUMAN Non-specific cutaneous vascular sympton [ICD-11: ME64]
P18825 ADA2C_HUMAN Pain [ICD-11: MG30-MG3Z]
P18825 ADA2C_HUMAN Peptic ulcer [ICD-11: DA61]
P18825 ADA2C_HUMAN Depression [ICD-11: 6A70-6A7Z]
P18825 ADA2C_HUMAN Heart failure [ICD-11: BD10-BD1Z]
P18825 ADA2C_HUMAN Orgasmic dysfunction [ICD-11: HA02]
P18825 ADA2C_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P18825 ADA2C_HUMAN Prostate disease [ICD-11: GA91]
P18825 ADA2C_HUMAN Sexual dysfunction [ICD-11: HA00-HA01]
P18825 ADA2C_HUMAN Coronavirus infection [ICD-11: 1D92]
P18825 ADA2C_HUMAN Asthma [ICD-11: CA23]
P18825 ADA2C_HUMAN Genetic cardiac arrhythmia [ICD-11: BC65]
P18825 ADA2C_HUMAN Dementia [ICD-11: 6D80-6D8Z]
P18825 ADA2C_HUMAN Unspecific body region injury [ICD-11: ND56]
P18825 ADA2C_HUMAN Unspecific substance harmful effect [ICD-11: NE6Z]
Q96KQ7 EHMT2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96KQ7 EHMT2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q96KQ7 EHMT2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q16665 HIF1A_HUMAN Adrenomedullary hyperfunction [ICD-11: 5A75]
Q16665 HIF1A_HUMAN Brain cancer [ICD-11: 2A00]
Q16665 HIF1A_HUMAN Lymphoma [ICD-11: 2A80-2A86]
Q16665 HIF1A_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q16665 HIF1A_HUMAN Pulmonary hypertension [ICD-11: BB01]
P68871 HBB_HUMAN Sickle-cell disorder [ICD-11: 3A51]
P68871 HBB_HUMAN Thalassaemia [ICD-11: 3A50]