Basic Information

Terpenoid ID TKC059165
Cell line 0
Protein target 1
DiseaseNCIT 0
ORDO 0
ICD 16

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC059165 MRC5 MRC5; MRC 5; MRCV; MRC-V; Medical Research Council cell strain-5 4230.0 nM GI50
TKC059165 PANC-1 Panc-1; PANC.1; Panc 1; PanC1; Panc1; PANC1; Panc-1-P 11580.0 nM GI50 C9120
TKC059165 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 6850.0 nM GI50 C9154 Orphanet_519
TKC059165 PC-3 PC3; PC.3 8370.0 nM GI50 C4863
TKC059165 A549 4550.0 nM GI50 C3512

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC059165 P11387 DNA topoisomerase 1 TOP1 23800 nM IC50
TKC059165 P11388 DNA topoisomerase 2-alpha TOP2A >250000 nM IC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P11387 TOP1_HUMAN Bacterial infection [ICD-11: 1A00-1C4Z]
P11387 TOP1_HUMAN Colorectal cancer [ICD-11: 2B91]
P11387 TOP1_HUMAN Lung cancer [ICD-11: 2C25]
P11387 TOP1_HUMAN Ovarian cancer [ICD-11: 2C73]
P11387 TOP1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11387 TOP1_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P11387 TOP1_HUMAN Human immunodeficiency virus disease [ICD-11: 1C60-1C62]
P11387 TOP1_HUMAN Stomach cancer [ICD-11: 2B72]
P11387 TOP1_HUMAN Brain cancer [ICD-11: 2A00]
P11387 TOP1_HUMAN Esophageal cancer [ICD-11: 2B70]
P11387 TOP1_HUMAN Myelodysplastic syndrome [ICD-11: 2A37]
P11387 TOP1_HUMAN Renal cell carcinoma [ICD-11: 2C90]
P11387 TOP1_HUMAN Gastrointestinal stromal tumour [ICD-11: 2B5B]
P11387 TOP1_HUMAN Lymphoma [ICD-11: 2A80-2A86]
P11387 TOP1_HUMAN Mature B-cell lymphoma [ICD-11: 2A85]
P11387 TOP1_HUMAN Bladder cancer [ICD-11: 2C94]
P11388 TOP2A_HUMAN Kaposi sarcoma [ICD-11: 2B57]
P11388 TOP2A_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P11388 TOP2A_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P11388 TOP2A_HUMAN Mature T-cell lymphoma [ICD-11: 2A90]