Basic Information

Terpenoid ID TKC100416
Cell line 0
Protein target 9
DiseaseNCIT 0
ORDO 0
ICD 40

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC100416 P05177 Cytochrome P450 1A2 CYP1A2 3162 nM AC50
TKC100416 P08913 Alpha-2A adrenergic receptor ADRA2A 31623 nM Kd
TKC100416 P10635 Cytochrome P450 2D6 CYP2D6 10000 nM Potency
TKC100416 P18089 Alpha-2B adrenergic receptor ADRA2B 32 nM Kd
TKC100416 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 EHMT2 37686 nM Potency
TKC100416 Q16665 Hypoxia-inducible factor 1-alpha HIF1A 25119 nM Potency
TKC100416 P08482 Muscarinic acetylcholine receptor M1 Chrm1 7943 nM Potency
TKC100416 P35348 Alpha-1A adrenergic receptor ADRA1A 32 nM Kd
TKC100416 P14618 Pyruvate kinase PKM PKM 13 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P08913 ADA2A_HUMAN Attention deficit hyperactivity disorder [ICD-11: 6A05]
P08913 ADA2A_HUMAN Opioid use disorder [ICD-11: 6C43]
P08913 ADA2A_HUMAN Substance abuse [ICD-11: 6C40]
P08913 ADA2A_HUMAN Pain [ICD-11: MG30-MG3Z]
P08913 ADA2A_HUMAN Depression [ICD-11: 6A70-6A7Z]
P08913 ADA2A_HUMAN Sexual dysfunction [ICD-11: HA00-HA01]
P08913 ADA2A_HUMAN Genetic cardiac arrhythmia [ICD-11: BC65]
P08913 ADA2A_HUMAN Dementia [ICD-11: 6D80-6D8Z]
P08913 ADA2A_HUMAN Obesity [ICD-11: 5B80-5B81]
P10635 CP2D6_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
P10635 CP2D6_HUMAN Malaria [ICD-11: 1F40-1F45]
P10635 CP2D6_HUMAN Migraine [ICD-11: 8A80]
P18089 ADA2B_HUMAN Substance abuse [ICD-11: 6C40]
P18089 ADA2B_HUMAN General pain disorder [ICD-11: 8E43]
P18089 ADA2B_HUMAN Pain [ICD-11: MG30-MG3Z]
P18089 ADA2B_HUMAN Hypertension [ICD-11: BA00-BA04]
P18089 ADA2B_HUMAN Genetic cardiac arrhythmia [ICD-11: BC65]
Q96KQ7 EHMT2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96KQ7 EHMT2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q96KQ7 EHMT2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q16665 HIF1A_HUMAN Adrenomedullary hyperfunction [ICD-11: 5A75]
Q16665 HIF1A_HUMAN Brain cancer [ICD-11: 2A00]
Q16665 HIF1A_HUMAN Lymphoma [ICD-11: 2A80-2A86]
Q16665 HIF1A_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q16665 HIF1A_HUMAN Pulmonary hypertension [ICD-11: BB01]
P35348 ADA1A_HUMAN Hypertension [ICD-11: BA00-BA04]
P35348 ADA1A_HUMAN Prostate hyperplasia [ICD-11: GA90]
P35348 ADA1A_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P35348 ADA1A_HUMAN Prostate cancer [ICD-11: 2C82]
P35348 ADA1A_HUMAN Pain [ICD-11: MG30-MG3Z]
P35348 ADA1A_HUMAN Abnormal micturition [ICD-11: MF50]
P35348 ADA1A_HUMAN Prostate disease [ICD-11: GA91]
P35348 ADA1A_HUMAN Depression [ICD-11: 6A70-6A7Z]
P35348 ADA1A_HUMAN Post-traumatic stress disorder [ICD-11: 6B40]
P35348 ADA1A_HUMAN Genetic cardiac arrhythmia [ICD-11: BC65]
P35348 ADA1A_HUMAN Glaucoma [ICD-11: 9C61]
P35348 ADA1A_HUMAN Sexual dysfunction [ICD-11: HA00-HA01]
P14618 KPYM_HUMAN Pain [ICD-11: MG30-MG3Z]
P14618 KPYM_HUMAN Renal cell carcinoma [ICD-11: 2C90]
P14618 KPYM_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]