Basic Information

Terpenoid ID TKC095493
Cell line 0
Protein target 32
DiseaseNCIT 0
ORDO 0
ICD 93

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC095493 HepG2 14125.0 nM Potency C3728 Orphanet_449
TKC095493 HEK293 11220.0 nM Potency
TKC095493 SN12C SN-12C 2023.0 nM GI50 C9385 Orphanet_217071
TKC095493 MDA-N MDAN 1675.0 nM GI50 C3802
TKC095493 NCI-H23 NCI.H23; NCI H23; H-23; H23; NCIH23 2123.0 nM GI50 C3512
TKC095493 ACHN 2618.0 nM GI50 C6975 Orphanet_319298
TKC095493 UO-31 UO.31; UO31; U031 2564.0 nM GI50 C9385 Orphanet_217071
TKC095493 HOP-92 HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 1919.0 nM GI50 C2926
TKC095493 HL-60 HL 60; HL.60 HL60; Human Leukemia-60 415.0 nM GI50 C9154 Orphanet_519
TKC095493 SF-539 SF-539; SF-539 BT; SF.539; SF 539 1786.0 nM GI50 C3796 Orphanet_251576
TKC095493 DU-145 DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 2065.0 nM GI50 C4863
TKC095493 SK-MEL-5 SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel 1600.0 nM GI50 C3510
TKC095493 Malme-3M MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer 2208.0 nM GI50 C3224
TKC095493 K562 K562; K.562; K 562; KO; GM05372; GM05372E 1186.0 nM GI50 C9110 Orphanet_521
TKC095493 OVCAR-3 Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 2056.0 nM GI50 C105555
TKC095493 A498 A498 2432.0 nM GI50 C9385 Orphanet_217071
TKC095493 MOLT-4 Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D 1337.0 nM GI50 C9142 Orphanet_99861
TKC095493 HOP-62 HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 2761.0 nM GI50 C3512
TKC095493 NCI/ADR-RES NCI/ADR-RES; NCI.ADR.RES; NCIADR.RES; NCI/ADRRES; NCIADRRES; ADR-RES; MCF-7/ADR; MCF-7/ADR-RES; MCF-7/AdrR; MCF-7/Adr; MCF-7/adr; MCF-7ADR; MCF7-ADR; MCF7ADR; OVCAR-8/ADR; OVCAR8/ADR 2897.0 nM GI50 C105555
TKC095493 U-251 U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) 1968.0 nM GI50 C60781 Orphanet_94
TKC095493 OVCAR-8 OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 2698.0 nM GI50 C105555
TKC095493 OVCAR-5 OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 2382.0 nM GI50 C105555
TKC095493 SNB-19 SNB.19; SNB19; Surgical Neurology Branch-19 3148.0 nM GI50 C60781 Orphanet_94
TKC095493 SR SR-786; SR786 1361.0 nM GI50 C37193 Orphanet_300895
TKC095493 MDA-MB-231 MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 1914.0 nM GI50 C5214
TKC095493 TK-10 TK.10; TK 10; TK10 3334.0 nM GI50 C4033 Orphanet_319276
TKC095493 SW-620 SW-620; SW 620; SW.620 1758.0 nM GI50 C4349
TKC095493 NCI-H522 NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 1837.0 nM GI50 C3512
TKC095493 M14 M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 1820.0 nM GI50 C3802
TKC095493 KM12 KM-12; KM.12 1754.0 nM GI50 C4910
TKC095493 NCI-H322M NCI.H322M; H322M; H-322M; H-322m 3581.0 nM GI50 C2923
TKC095493 RPMI-8226 RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson 1208.0 nM GI50 C3242 Orphanet_29073
TKC095493 OVCAR-4 OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 2123.0 nM GI50 C105555
TKC095493 LOX IMVI LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX 1782.0 nM GI50 C3802
TKC095493 BT-549 BT 549; BT.549; BT549 2244.0 nM GI50 C4194
TKC095493 SK-MEL-2 SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 1820.0 nM GI50 C3224
TKC095493 A549 3048.0 nM GI50 C3512
TKC095493 SNB-75 SNB.75; SNB75; Surgical Neurology Branch-75 2576.0 nM GI50 C3058 Orphanet_360
TKC095493 HCC 2998 HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 1726.0 nM GI50 C4349
TKC095493 HCT-15 HCT-15; HCT.15; HCT15 1995.0 nM GI50 C4349
TKC095493 HCT-116 HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 1671.0 nM GI50 C4910
TKC095493 SF-268 SF-268; SF.268; SF 268 2099.0 nM GI50 C60781 Orphanet_94
TKC095493 MCF7 1837.0 nM GI50 C4194
TKC095493 EKVX 2985.0 nM GI50 C3512
TKC095493 PC-3 PC3; PC.3 2259.0 nM GI50 C4863
TKC095493 T47D 1845.0 nM GI50 C4194
TKC095493 SK-OV-3 SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 4467.0 nM GI50 C7978
TKC095493 UACC-62 UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 1455.0 nM GI50 C3224
TKC095493 NCI-H460 NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 1923.0 nM GI50 C4450
TKC095493 MDA-MB-435 MDA-MB435; MDAMB435; MDA.MB.435; MDA-435; MDA 435; MDA435; MD Anderson-Metastatic Breast-435 1626.0 nM GI50 C3802
TKC095493 CAKI-1 CAL 1; Centre Antoine Lacassagne-1 3365.0 nM GI50 C3224
TKC095493 IGROV-1 Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P 2812.0 nM GI50 C7979 Orphanet_454723
TKC095493 SF-295 SF-295; SF.295; SF 295 1778.0 nM GI50 C3058 Orphanet_360
TKC095493 Hs-578T HS 578T; Hs-578T; HS-578T; Hs_578t; Hs-578-T; HS-578-T; Hs 578.T; HS578T; Hs578T; Hs578t; HS0578T; 578T; HS578; Hs578; Homo sapiens No. 578, tumor cells 2143.0 nM GI50 C4194
TKC095493 786-0 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT 2404.0 nM GI50 C9385 Orphanet_217071
TKC095493 CCRF-CEM CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C 150.0 nM GI50 C7953 Orphanet_99861
TKC095493 UACC-257 UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 1845.0 nM GI50 C3224
TKC095493 NCI-H226 NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 2477.0 nM GI50 C45662 Orphanet_50251
TKC095493 HT-29 HT 29; HT29 2393.0 nM GI50 C4349
TKC095493 SK-MEL-28 SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 1596.0 nM GI50 C3510
TKC095493 COLO 205 Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 1928.0 nM GI50 C4349
TKC095493 RXF 393 RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL 1472.0 nM GI50 C9385 Orphanet_217071

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC095493 P04062 Lysosomal acid glucosylceramidase GBA1 10000 nM Potency
TKC095493 P10636 Microtubule-associated protein tau MAPT 7943 nM Potency
TKC095493 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 9200 nM Potency
TKC095493 P08684 Cytochrome P450 3A4 CYP3A4 1585 nM AC50
TKC095493 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 8200 nM Potency
TKC095493 P43220 Glucagon-like peptide 1 receptor GLP1R 6310 nM Potency
TKC095493 P84022 Mothers against decapentaplegic homolog 3 SMAD3 12589 nM Potency
TKC095493 Q06710 Paired box protein Pax-8 PAX8 8190 nM AC50
TKC095493 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 20596 nM Potency
TKC095493 Q99700 Ataxin-2 ATXN2 31623 nM Potency
TKC095493 O75496 Geminin GMNN 9200 nM Potency
TKC095493 P38398 Breast cancer type 1 susceptibility protein BRCA1 35481 nM Potency
TKC095493 P05177 Cytochrome P450 1A2 CYP1A2 3981 nM AC50
TKC095493 P07550 Beta-2 adrenergic receptor ADRB2 28184 nM Potency
TKC095493 P10635 Cytochrome P450 2D6 CYP2D6 3981 nM AC50
TKC095493 P11712 Cytochrome P450 2C9 CYP2C9 316 nM Potency
TKC095493 P32245 Melanocortin receptor 4 MC4R >64584 nM IC50
TKC095493 P33261 Cytochrome P450 2C19 CYP2C19 3162 nM AC50
TKC095493 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 16354 nM Potency
TKC095493 P63096 Guanine nucleotide-binding protein G GNAI1 50119 nM Potency
TKC095493 Q6W5P4 Neuropeptide S receptor NPSR1 10000 nM Potency
TKC095493 O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B ALOX15B 3162 nM Potency
TKC095493 Q9F4F7 4'-phosphopantetheinyl transferase ffp ffp 70795 nM Potency
TKC095493 P10520 Streptokinase A ska 1801 nM EC50
TKC095493 Q16665 Hypoxia-inducible factor 1-alpha HIF1A 3162 nM Potency
TKC095493 Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B BAZ2B 89125 nM Potency
TKC095493 P16050 Polyunsaturated fatty acid lipoxygenase ALOX15 ALOX15 3162 nM Potency
TKC095493 Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F APOBEC3F 3548 nM Potency
TKC095493 P51450 Nuclear receptor ROR-gamma Rorc 12589 nM Potency
TKC095493 P02545 Prelamin-A/C LMNA 12589 nM Potency
TKC095493 P04637 Cellular tumor antigen p53 TP53 3162 nM Potency
TKC095493 Q194T2 Non-structural protein 1 NS1 12589 nM Potency
TKC095493 P62826 GTP-binding nuclear protein Ran RAN 14581 nM Potency
TKC095493 P11166 Solute carrier family 2, facilitated glucose transporter member 1 SLC2A1 8 % Inhibition
TKC095493 O61059 Glucose transporter LmGT2 7 % Inhibition
TKC095493 O97467 Hexose transporter 1 ht1 7 % Inhibition

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P10636 TAU_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P10636 TAU_HUMAN Alzheimer disease [ICD-11: 8A20]
P10636 TAU_HUMAN Mild neurocognitive disorder [ICD-11: 6D71]
P10636 TAU_HUMAN Choreiform disorder [ICD-11: 8A01]
P10636 TAU_HUMAN Parkinsonism [ICD-11: 8A00]
P10636 TAU_HUMAN Central nervous system disease [ICD-11: 8A04-8D87]
P10636 TAU_HUMAN Neurodegenerative disorder [ICD-11: 8A20-8A23]
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Liver cancer [ICD-11: 2C12]
O75874 IDHC_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
O75874 IDHC_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
O75874 IDHC_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P43220 GLP1R_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P43220 GLP1R_HUMAN Obesity [ICD-11: 5B80-5B81]
P43220 GLP1R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P43220 GLP1R_HUMAN Type-1/2 diabete [ICD-11: 5A10-5A11]
P43220 GLP1R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P43220 GLP1R_HUMAN Diabetes mellitus [ICD-11: 5A10]
P43220 GLP1R_HUMAN Dyspepsia [ICD-11: MD92]
P43220 GLP1R_HUMAN Irritable bowel syndrome [ICD-11: DD91]
P43220 GLP1R_HUMAN Intracranial injury [ICD-11: NA07]
P43220 GLP1R_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
P07550 ADRB2_HUMAN Glaucoma [ICD-11: 9C61]
P07550 ADRB2_HUMAN Asthma [ICD-11: CA23]
P07550 ADRB2_HUMAN Chronic obstructive pulmonary disease [ICD-11: CA22]
P07550 ADRB2_HUMAN Conduction disorder [ICD-11: BC63]
P07550 ADRB2_HUMAN Melanoma [ICD-11: 2C30]
P07550 ADRB2_HUMAN Preterm labour/delivery [ICD-11: JB00]
P07550 ADRB2_HUMAN Sleep-related breathing disorder [ICD-11: 7A4Z]
P07550 ADRB2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P07550 ADRB2_HUMAN Stomach cancer [ICD-11: 2B72]
P07550 ADRB2_HUMAN Hypertension [ICD-11: BA00-BA04]
P07550 ADRB2_HUMAN Supraventricular tachyarrhythmia [ICD-11: BC81]
P07550 ADRB2_HUMAN Cachexia [ICD-11: MG20]
P07550 ADRB2_HUMAN Dermal/subcutaneous connective tissue atrophy/degeneration [ICD-11: EE40]
P07550 ADRB2_HUMAN Skin and skin-structure infection [ICD-11: 1F28-1G0Z]
P07550 ADRB2_HUMAN Bladder disorder [ICD-11: GC01]
P07550 ADRB2_HUMAN Obesity [ICD-11: 5B80-5B81]
P07550 ADRB2_HUMAN Ejaculatory dysfunction [ICD-11: HA03]
P07550 ADRB2_HUMAN Cardiovascular disease [ICD-11: BA00-BE2Z]
P10635 CP2D6_HUMAN Insomnia [ICD-11: 7A00-7A0Z]
P10635 CP2D6_HUMAN Malaria [ICD-11: 1F40-1F45]
P10635 CP2D6_HUMAN Migraine [ICD-11: 8A80]
P11712 CP2C9_HUMAN Bacterial infection [ICD-11: 1A00-1C4Z]
P32245 MC4R_HUMAN Acute diabete complication [ICD-11: 5A2Y]
P32245 MC4R_HUMAN Hypoactive sexual desire dysfunction [ICD-11: HA00]
P32245 MC4R_HUMAN Intellectual development disorder [ICD-11: LD90]
P32245 MC4R_HUMAN Large intestine motility disorder [ICD-11: DB32]
P32245 MC4R_HUMAN Obesity [ICD-11: 5B80-5B81]
P32245 MC4R_HUMAN Pituitary hypofunction [ICD-11: 5A61]
P32245 MC4R_HUMAN Sexual dysfunction [ICD-11: HA00-HA01]
P32245 MC4R_HUMAN Alzheimer disease [ICD-11: 8A20]
P32245 MC4R_HUMAN Asthma [ICD-11: CA23]
P32245 MC4R_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
P32245 MC4R_HUMAN General pain disorder [ICD-11: 8E43]
P32245 MC4R_HUMAN Atopic eczema [ICD-11: EA80]
P32245 MC4R_HUMAN Metabolic disorder [ICD-11: 5C50-5D2Z]
P32245 MC4R_HUMAN Type 2 diabetes mellitus [ICD-11: 5A11]
P32245 MC4R_HUMAN Anorexia nervosa [ICD-11: 6B80]
P32245 MC4R_HUMAN Cachexia [ICD-11: MG20]
Q16665 HIF1A_HUMAN Adrenomedullary hyperfunction [ICD-11: 5A75]
Q16665 HIF1A_HUMAN Brain cancer [ICD-11: 2A00]
Q16665 HIF1A_HUMAN Lymphoma [ICD-11: 2A80-2A86]
Q16665 HIF1A_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q16665 HIF1A_HUMAN Pulmonary hypertension [ICD-11: BB01]
P04637 P53_HUMAN Arterial occlusive disease [ICD-11: BD40]
P04637 P53_HUMAN Lip/oral cavity/pharynx neoplasm [ICD-11: 2B6E]
P04637 P53_HUMAN Metastatic liver/bile duct neoplasm [ICD-11: 2D80]
P04637 P53_HUMAN Transplant rejection [ICD-11: NE84]
P04637 P53_HUMAN Ovarian dysfunction [ICD-11: 5A80]
P04637 P53_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P04637 P53_HUMAN Bladder cancer [ICD-11: 2C94]
P04637 P53_HUMAN Brain cancer [ICD-11: 2A00]
P04637 P53_HUMAN Colorectal cancer [ICD-11: 2B91]
P04637 P53_HUMAN Esophageal cancer [ICD-11: 2B70]
P04637 P53_HUMAN Head and neck cancer [ICD-11: 2D42]
P04637 P53_HUMAN Mature B-cell leukaemia [ICD-11: 2A82]
P04637 P53_HUMAN Myelodysplastic syndrome [ICD-11: 2A37]
P04637 P53_HUMAN Ovarian cancer [ICD-11: 2C73]
P04637 P53_HUMAN Pancreatic cancer [ICD-11: 2C10]
P04637 P53_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P04637 P53_HUMAN Stomach cancer [ICD-11: 2B72]
P04637 P53_HUMAN Cervical cancer [ICD-11: 2C77]
P04637 P53_HUMAN Endometrial cancer [ICD-11: 2C76]
P04637 P53_HUMAN Fallopian tube cancer [ICD-11: 2C74]
P04637 P53_HUMAN Liposarcoma [ICD-11: 2B59]
P04637 P53_HUMAN Malignant haematopoietic neoplasm [ICD-11: 2B33]
P04637 P53_HUMAN Peritoneal cancer [ICD-11: 2C51]
P04637 P53_HUMAN Toxicity [ICD-11: N.A.]
P04637 P53_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P04637 P53_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
P04637 P53_HUMAN Kidney failure [ICD-11: GB60-GB6Z]
P04637 P53_HUMAN Hearing disorder [ICD-11: AB50-AB57]
P11166 GTR1_HUMAN Skin disease [ICD-11: EA00-EM0Z]
O97467 O97467_PLAFA Malaria [ICD-11: 1F40-1F45]