Basic Information

Terpenoid ID TKC112813
Cell line 0
Protein target 5
DiseaseNCIT 0
ORDO 0
ICD 7

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC112813 Vero VERO; VeroCCL81; Vero 81; Vero-81; Verda reno 92000.0 nM IC50

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC112813 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 20596 nM Potency
TKC112813 Q9NPD5 Solute carrier organic anion transporter family member 1B3 SLCO1B3 106 % Inhibition
TKC112813 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 SLCO1B1 102 % Inhibition
TKC112813 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 7080 nM Potency
TKC112813 P02545 Prelamin-A/C LMNA 22387 nM Potency
TKC112813 O75604 Ubiquitin carboxyl-terminal hydrolase 2 USP2 3981 nM Potency
TKC112813 Q9UHC9 NPC1-like intracellular cholesterol transporter 1 NPC1L1 3400 nM EC50

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]
O75604 UBP2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q9UHC9 NPCL1_HUMAN Hyper-lipoproteinaemia [ICD-11: 5C80]