Basic Information

Terpenoid ID TKC105356
Chirality TKC012929
Cell line 0
Protein target 16
DiseaseNCIT 0
ORDO 0
ICD 19

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC105356 HEK293 11220.0 nM Potency

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC105356 Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH2 112 nM Potency
TKC105356 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 39811 nM Potency
TKC105356 Q9UNA4 DNA polymerase iota POLI 50119 nM Potency
TKC105356 O75496 Geminin GMNN 14125 nM Potency
TKC105356 O89049 Thioredoxin reductase 1, cytoplasmic Txnrd1 35481 nM Potency
TKC105356 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 EHMT2 355 nM Potency
TKC105356 P54132 Bloom syndrome protein BLM 19953 nM Potency
TKC105356 Q01453 Peripheral myelin protein 22 PMP22 42562 nM Potency
TKC105356 Q6W5P4 Neuropeptide S receptor NPSR1 6310 nM Potency
TKC105356 O00255 Menin MEN1 5012 nM Potency
TKC105356 P02791 Ferritin light chain FTL 19953 nM Potency
TKC105356 P25779 Cruzipain 10000 nM Potency
TKC105356 Q9Y253 DNA polymerase eta POLH 44668 nM Potency
TKC105356 P02545 Prelamin-A/C LMNA 18 nM Potency
TKC105356 P0A6C1 Endonuclease 4 nfo 35481 nM Potency
TKC105356 Q99549 M-phase phosphoprotein 8 MPHOSPH8 708 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q12809 KCNH2_HUMAN Heart failure [ICD-11: BD10-BD1Z]
Q12809 KCNH2_HUMAN Sleep-wake disorder [ICD-11: 7A00-7B2Z]
Q12809 KCNH2_HUMAN Malaria [ICD-11: 1F40-1F45]
Q12809 KCNH2_HUMAN Multiple sclerosis [ICD-11: 8A40]
Q12809 KCNH2_HUMAN Pain [ICD-11: MG30-MG3Z]
Q12809 KCNH2_HUMAN Cardiac arrhythmia [ICD-11: BC9Z]
Q12809 KCNH2_HUMAN Angina pectoris [ICD-11: BA40]
Q12809 KCNH2_HUMAN Genetic cardiac arrhythmia [ICD-11: BC65]
Q12809 KCNH2_HUMAN Ovarian cancer [ICD-11: 2C73]
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]
Q96KQ7 EHMT2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96KQ7 EHMT2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q96KQ7 EHMT2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P25779 CYSP_TRYCR Parasitic worm infestation [ICD-11: 1F90]
P25779 CYSP_TRYCR Malaria [ICD-11: 1F40-1F45]