Terpenoid ID | TKC134761 | |
Cell line | 11 | |
Protein target | 1 | |
DiseaseNCIT | 12 | |
ORDO | 4 | |
ICD | 15 |
ID | Cell Line | Synonyms | Value | Unit | Type | NCIt | ORDO |
---|---|---|---|---|---|---|---|
TKC134761 | RAW264.7 | RAW264 | 100.0 | nM | IC50 | C21604 | |
TKC134761 | MCF7 | 10.0 | ug.mL-1 | IC50 | C4194 | ||
TKC134761 | K562 | K562; K.562; K 562; KO; GM05372; GM05372E | 17000.0 | nM | IC50 | C9110 | Orphanet_521 |
TKC134761 | HeLa | HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri | 6000.0 | nM | IC50 | C27677 | |
TKC134761 | DU-145 | DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 | 3100.0 | nM | IC50 | C4863 | |
TKC134761 | U-937 | U937; U 937 | 2200.0 | nM | IC50 | C8263 | Orphanet_514 |
TKC134761 | NCI-H1975 | H1975; H-1975; NCIH1975 | 13000.0 | nM | IC50 | C3512 | |
TKC134761 | A549 | 6200.0 | nM | IC50 | C3512 | ||
TKC134761 | MOLT-4 | Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D | 5500.0 | nM | IC50 | C9142 | Orphanet_99861 |
TKC134761 | HL-60 | HL 60; HL.60 HL60; Human Leukemia-60 | 2400.0 | nM | IC50 | C9154 | Orphanet_519 |
TKC134761 | HCT-116 | HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 | 4430.0 | nM | IC50 | C4910 | |
TKC134761 | HT-29 | HT 29; HT29 | 3370.0 | nM | IC50 | C4349 |
ID | Uniport | Pref_name | Gene name | value | unit | type |
---|---|---|---|---|---|---|
TKC134761 | P40763 | Signal transducer and activator of transcription 3 | STAT3 | 48 | % | Inhibition |
Uniport ID | Uniport Name | ICD-11 |
---|---|---|
P40763 | STAT3_HUMAN | Psoriasis [ICD-11: EA90] |
P40763 | STAT3_HUMAN | Brain cancer [ICD-11: 2A00] |
P40763 | STAT3_HUMAN | Colorectal cancer [ICD-11: 2B91] |
P40763 | STAT3_HUMAN | Liver cancer [ICD-11: 2C12] |
P40763 | STAT3_HUMAN | Malignant digestive organ neoplasm [ICD-11: 2C11] |
P40763 | STAT3_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
P40763 | STAT3_HUMAN | Pancreatic cancer [ICD-11: 2C10] |
P40763 | STAT3_HUMAN | Respiratory infection [ICD-11: CA07-CA4Z] |
P40763 | STAT3_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
P40763 | STAT3_HUMAN | Immune system disease [ICD-11: 4A01-4B41] |
P40763 | STAT3_HUMAN | Postoperative inflammation [ICD-11: 1A00-CA43] |
P40763 | STAT3_HUMAN | Mature B-cell leukaemia [ICD-11: 2A82] |
P40763 | STAT3_HUMAN | Multiple myeloma [ICD-11: 2A83] |
P40763 | STAT3_HUMAN | Mycosis fungoides [ICD-11: 2B01] |
P40763 | STAT3_HUMAN | Ulcerative colitis [ICD-11: DD71] |
P40763 | STAT3_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |