Basic Information

Terpenoid ID TKC164433
Chirality TKC164431
Cell line 0
Protein target 11
DiseaseNCIT 0
ORDO 0
ICD 21

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC164433 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 29093 nM Potency
TKC164433 P84022 Mothers against decapentaplegic homolog 3 SMAD3 15849 nM Potency
TKC164433 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 11220 nM Potency
TKC164433 Q77YF9 Protein Vpr vpr 22387 nM Potency
TKC164433 Q99700 Ataxin-2 ATXN2 11220 nM Potency
TKC164433 P27695 DNA-(apurinic or apyrimidinic site) endonuclease APEX1 9466 nM Potency
TKC164433 O75496 Geminin GMNN 14581 nM Potency
TKC164433 P83916 Chromobox protein homolog 1 CBX1 56234 nM Potency
TKC164433 P63096 Guanine nucleotide-binding protein G GNAI1 12589 nM Potency
TKC164433 Q03164 Histone-lysine N-methyltransferase 2A KMT2A 100000 nM Potency
TKC164433 P11308 Transcriptional regulator ERG ERG 44668 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
P84022 SMAD3_HUMAN Herpes simplex infection [ICD-11: 1F00]
P84022 SMAD3_HUMAN Kidney fibrosis [ICD-11: GC01]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
P27695 APEX1_HUMAN Retinopathy [ICD-11: 9B71]
P27695 APEX1_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P27695 APEX1_HUMAN Ocular cancer [ICD-11: 2D00-2D07]
P27695 APEX1_HUMAN Brain cancer [ICD-11: 2A00]
P27695 APEX1_HUMAN Melanoma [ICD-11: 2C30]