Basic Information
| Terpenoid ID | TKC123088 |
|
| Chirality | TKC105710 | |
| Cell line | 0 | |
| Protein target | 25 | |
| DiseaseNCIT | 0 | |
| ORDO | 0 | |
| ICD | 66 |
| Terpenoid ID | TKC123088 |
|
| Chirality | TKC105710 | |
| Cell line | 0 | |
| Protein target | 25 | |
| DiseaseNCIT | 0 | |
| ORDO | 0 | |
| ICD | 66 |
| ID | Cell Line | Synonyms | Value | Unit | Type | NCIt | ORDO |
|---|---|---|---|---|---|---|---|
| TKC123088 | CCRF-CEM | CCRF/CEM; CCRFCEM; CCRF.CEM; CCRF CEM; CCRF; CEM; CEM-CCRF; CEM-CCRF (CAMR); CCRF/CEM/0; CEM/0; CEM-0; CCRF-CEM/S; GM03671; GM03671C | 30000.0 | nM | IC50 | C7953 | Orphanet_99861 |
| TKC123088 | B16 | B-16; B16 melanoma; B16 subline B78; B78 | 7900.0 | nM | IC50 | C21790 | |
| TKC123088 | HepG2 | 3.0 | ug.mL-1 | IC50 | C3728 | Orphanet_449 | |
| TKC123088 | A549 | 3100.0 | nM | IC50 | C3512 | ||
| TKC123088 | MCF7 | 10000.0 | nM | IC50 | C4194 | ||
| TKC123088 | MDA-MB-238 | 195.0 | uM | TCS50 | |||
| TKC123088 | LNCaP | LNCAP; LNCap; Ln-Cap; Lymph Node Carcinoma of the prostate | 27.0 | uM | ED50 | C4863 | |
| TKC123088 | DU-145 | DU-145; Du-145; DU 145; DU_145; DU.145; Duke University 145 | 22000.0 | nM | IC50 | C4863 | |
| TKC123088 | OVCAR-3 | Ovcar-3; OVCAR 3; OVCAR.3; NIH:OVCAR-3; NIH:Ovcar-3; NIH:OVCAR3; NIH-OVCAR-3; NIHOVCAR3; OVCAR3; Ovcar3 | 1.0 | ug.mL-1 | IC50 | C105555 | |
| TKC123088 | Caco-2 | CaCo-2; CACO-2; Caco 2; CACO 2; CACO2; CaCo2; CaCO2; Caco2; Caco-2/ATCC; Caco-II | 194.0 | uM | TCS50 | C4349 | |
| TKC123088 | SK-MEL3 | SK-Mel-3; Sk-mel-3; SK-MEL3; SK-Mel3; SKMEL3 | 3.0 | uM | TCS50 | C3510 | |
| TKC123088 | K562 | K562; K.562; K 562; KO; GM05372; GM05372E | 21960.0 | nM | IC50 | C9110 | Orphanet_521 |
| TKC123088 | CEM-VCR 1/F3 | CEM/VCR R | 19.0 | uM | TCS50 | C7953 | Orphanet_99861 |
| TKC123088 | CEM-VCR 1/D/5 | CEM/VCR R | 24.0 | uM | TCS50 | C7953 | Orphanet_99861 |
| TKC123088 | CEM-VCR | CEM/VCR R | 69.0 | uM | TCS50 | C7953 | Orphanet_99861 |
| TKC123088 | H9 | HT clone H9; HT(H9); H 9; H-9 | 1400.0 | nM | EC50 | C3366 | Orphanet_3162 |
| TKC123088 | HOP-62 | HOP 62; Hop 62; HOP.62; HOP62; Hop62; Hopkins-62 | 794.0 | nM | GI50 | C3512 | |
| TKC123088 | SK-MEL-2 | SK-Mel-2; SK-Mel 2; SK-mel-2; SK-MEL2; SK.MEL.2; SK Mel 2; SK MEL 2; SKMEL-2; SKMEL2; SKmel2; SK-ML2; SKml2 | 7000.0 | nM | IC50 | C3224 | |
| TKC123088 | HCT-116 | HCT-116; HCT.116; HCT_116; HCT116; HCT116wt; CoCL2 | 10000.0 | nM | IC50 | C4910 | |
| TKC123088 | M14 | M14-MEL; UCLA-SO-M14; UCLA SO M14; UCLA-SO-14; UCLASO-M14; Melanoma 14; M-14 | 10280.0 | nM | GI50 | C3802 | |
| TKC123088 | UACC-257 | UACC 257; UACC.257; UACC257; University of Arizona Cell Culture-257 | 1500.0 | nM | GI50 | C3224 | |
| TKC123088 | PC-3 | PC3; PC.3 | 10000.0 | nM | IC50 | C4863 | |
| TKC123088 | ECV-304 | ECV 304; ECV304; ECV; E304; T24(ECV304) | 1.0 | ug.mL-1 | IC50 | C4912 | |
| TKC123088 | SK-MEL | SK-Mel-1; SK Mel 1; SK-Mel 1; SK-Mel1; SKMEL-1; SkMEL-1; SKMEL1; SK 1 | 35000.0 | nM | IC50 | C3224 | |
| TKC123088 | L132 | L132; L 132 | 1.0 | ug ml-1 | ED50 | C27677 | |
| TKC123088 | MOLT-4 | Molt-4; MOLT 4; Molt 4; MOLT.4; MOLT4; Molt4; GM02219; GM02219C; GM2219C; GM02219D | 1.0 | ug ml-1 | ED50 | C9142 | Orphanet_99861 |
| TKC123088 | Jurkat | JURKAT; JM; JM-Jurkat; Jurkat-FHCRC; Jurkat FHCRC; FHCRC-11; FHCRC subclone 11; FCCH1024 | 27.0 | nM | IC50 | C7953 | Orphanet_99861 |
| TKC123088 | BRISTOL8 | BRISTOL 8; Bristol-8; BRISTOL-8; BRISTOL8; Bri-8; BRI-8; BRI 8; GM03357; GM3357; GM03357B | 1.0 | ug ml-1 | ED50 | ||
| TKC123088 | U-937 | U937; U 937 | 1.0 | ug ml-1 | ED50 | C8263 | Orphanet_514 |
| TKC123088 | Vero | VERO; VeroCCL81; Vero 81; Vero-81; Verda reno | 72100.0 | nM | IC50 | ||
| TKC123088 | Bel-7402 | Bel-7402; BEL 7402; Bel 7402; BEL7402; Bel7402 | 43390.0 | nM | IC50 | C27677 | |
| TKC123088 | C6 | C-6; C 6; RGC-6; RGC6; RGc6 | 90690.0 | nM | IC50 | C64069 | |
| TKC123088 | J774 | J-774 | 44000.0 | nM | IC50 | C134780 | |
| TKC123088 | NCI-H460 | NCI.H460; H460; H-460; NCIH460; NCI-HUT-460; NCI-460 | 5.0 | ug.mL-1 | GI50 | C4450 | |
| TKC123088 | ME-180 | Me-180; ME 180; ME180 | 28.0 | ug.mL-1 | GI50 | C27676 | Orphanet_213767 |
| TKC123088 | BXPC-3 | BxPc-3; BXPC-3; Bx-PC3; BXPC3; BxPC3; BxPc3; Biopsy xenograft of Pancreatic Carcinoma line-3 | 1.0 | ug.mL-1 | GI50 | C9120 | |
| TKC123088 | SF-268 | SF-268; SF.268; SF 268 | 1.0 | ug.mL-1 | GI50 | C60781 | Orphanet_94 |
| TKC123088 | KM-20L2 | KM-20L2; KM 20L2; KM 2012 | 3.0 | ug.mL-1 | GI50 | C4349 | |
| TKC123088 | HeLa | HELA; Hela; He La; He-La; HeLa-CCL2; Henrietta Lacks cells; Helacyton gartleri | 1.0 | ug.mL-1 | IC50 | C27677 | |
| TKC123088 | HBL-100 | HBL 100; HBL100 | 5.0 | ug.mL-1 | IC50 | ||
| TKC123088 | DLD-1 | DLD 1; DLD1; CoCL3 | 11870.0 | nM | IC50 | C4349 | |
| TKC123088 | A-375 | A 375; A375; A375-MEL; A375-mel; A375mel | 12000.0 | nM | EC50 | C3802 | |
| TKC123088 | Daoy | DAOY; D324 Med; D-324 Med; D324 MED; D-324MED; D324 | 11000.0 | nM | IC50 | C129442 | Orphanet_616 |
| TKC123088 | CEM-SS | CEM-ss; CEM SS; CEM_SS; CEMss; CEM-Syncitial Sensitive | 5900.0 | nM | CC50 | C7953 | Orphanet_99861 |
| TKC123088 | Lu1 | Lu1 | 41.0 | uM | ED50 | C21678 | |
| TKC123088 | Col2 | Col-2; Col2 | 44.0 | uM | ED50 | C4910 | |
| TKC123088 | HUVEC | HUV-EC-C; HUVEC | 29.0 | uM | ED50 | ||
| TKC123088 | PANC-1 | Panc-1; PANC.1; Panc 1; PanC1; Panc1; PANC1; Panc-1-P | 44000.0 | nM | IC50 | C9120 | |
| TKC123088 | P388D1 | P-388D1; P388-D1; P388.D1; P3 88 D1 | 70.0 | % | Activity | C21602 | |
| TKC123088 | WI-38 VA13 | WI 38 VA13 subline 2RA; WI 38 VA-13 subline 2RA; WI 38VA13 subline 2RA; WI-38 VA13 sub 2 RA; WI38-VA13 subline 2RA; WI38 VA13/2RA; WI38VA13/2RA; VA13 2RA; WI-38 VA13; WI 38 VA 13; WI38-VA13; WI38/VA13; WI38VA13; VA-13; VA13; AG07217; AG7217 | 11600.0 | nM | IC50 | ||
| TKC123088 | MDA-MB-231 | MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231 | 4.0 | ug.mL-1 | IC50 | C5214 | |
| TKC123088 | HL-60 | HL 60; HL.60 HL60; Human Leukemia-60 | 2.0 | ug.mL-1 | IC50 | C9154 | Orphanet_519 |
| TKC123088 | SW-1736 | SW-1736; SW 1736 | 11600.0 | nM | IC50 | C3878 | Orphanet_142 |
| TKC123088 | 8505C | 8505c | 6700.0 | nM | IC50 | C3878 | Orphanet_142 |
| TKC123088 | SW480 | SW-480; SW 480; SW480E | 6400.0 | nM | IC50 | C4349 | |
| TKC123088 | HCT-8 | HCT-8; HCT8 | 13100.0 | nM | IC50 | C4349 | |
| TKC123088 | FaDu | FaDU; FADU | 10190.0 | nM | IC50 | C4043 | Orphanet_494547 |
| TKC123088 | A-431 | A431; A431/P | 12600.0 | nM | IC50 | C4819 | |
| TKC123088 | SK-OV-3 | SKOV-3; SK-OV3; SK.OV.3; SKOV3; Skov3; SKO3 | 10000.0 | nM | IC50 | C7978 | |
| TKC123088 | HCT-15 | HCT-15; HCT.15; HCT15 | 12000.0 | nM | IC50 | C4349 | |
| TKC123088 | SW948 | SW-948; SW 948 | 10500.0 | nM | IC50 | C4349 | |
| TKC123088 | RPMI-8226 | RPMI 8226; RPMI.8226; RPMI8226; RPMI no. 8226; RPMI no 8226; RPMI #8226; 8226; RPMI 8226/S; RPMI-8226S; RPMI8226/S; 8226/S; Roswell Park Memorial Institute 8226; GM02132; GM2132; GM 2132; GM02132C; Simpson | 7362.0 | nM | GI50 | C3242 | Orphanet_29073 |
| TKC123088 | SR | SR-786; SR786 | 5012.0 | nM | GI50 | C37193 | Orphanet_300895 |
| TKC123088 | EKVX | 15849.0 | nM | GI50 | C3512 | ||
| TKC123088 | HOP-92 | HOP 92; HOP.92; HOP92; Hop92; Hopkins-92 | 3162.0 | nM | GI50 | C2926 | |
| TKC123088 | NCI-H226 | NCI.H226; NCI H226; H226; H-226; HUT-226; HUT 226; NCIH226 | 12589.0 | nM | GI50 | C45662 | Orphanet_50251 |
| TKC123088 | NCI-H23 | NCI.H23; NCI H23; H-23; H23; NCIH23 | 2512.0 | nM | GI50 | C3512 | |
| TKC123088 | NCI-H322M | NCI.H322M; H322M; H-322M; H-322m | 10000.0 | nM | GI50 | C2923 | |
| TKC123088 | NCI-H522 | NCI.H522; H522; H-522; NCI-522; NCI522; NCIH522 | 3162.0 | nM | GI50 | C3512 | |
| TKC123088 | COLO 205 | Colo 205; CoLo 205; COLO-205; Colo-205; COLO.205; Colo205; COLO205; Co 205; Colorado 205 | 4634.0 | nM | GI50 | C4349 | |
| TKC123088 | HCC 2998 | HCC-2998; HCC.2998; HCC 2998; Hamon Cancer Center 2998 | 6310.0 | nM | GI50 | C4349 | |
| TKC123088 | KM12 | KM-12; KM.12 | 5929.0 | nM | GI50 | C4910 | |
| TKC123088 | SF-295 | SF-295; SF.295; SF 295 | 22000.0 | nM | IC50 | C3058 | Orphanet_360 |
| TKC123088 | SF-539 | SF-539; SF-539 BT; SF.539; SF 539 | 3981.0 | nM | GI50 | C3796 | Orphanet_251576 |
| TKC123088 | SNB-19 | SNB.19; SNB19; Surgical Neurology Branch-19 | 12589.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC123088 | SNB-75 | SNB.75; SNB75; Surgical Neurology Branch-75 | 7943.0 | nM | GI50 | C3058 | Orphanet_360 |
| TKC123088 | U-251 | U-251 MG; U-251-MG; U-251_MG; U251-MG; U251MG; U-251; U251; U251n; U251N; 251 MG; 251MG; 251 MG(6) | 5012.0 | nM | GI50 | C60781 | Orphanet_94 |
| TKC123088 | LOX IMVI | LOX/IMVI; LOX IMVI; LOXIM-VI; LOXIMVI; LOX | 11272.0 | nM | GI50 | C3802 | |
| TKC123088 | Malme-3M | MALME-3M; MALME 3M; Malme-3 M; MALME.3M; Malme3M; MALME3M; Malme-3 Monolayer | 7586.0 | nM | GI50 | C3224 | |
| TKC123088 | MDA-MB-435 | MDA-MB435; MDAMB435; MDA.MB.435; MDA-435; MDA 435; MDA435; MD Anderson-Metastatic Breast-435 | 12589.0 | nM | GI50 | C3802 | |
| TKC123088 | SK-MEL-28 | SK-Mel-28; SK.MEL.28; SK-MEL 28; SK MEL-28; SK MEL 28; SK Mel 28; SKMel-28; SKMEL-28; SK-MEL28; SK-Mel28; SK Mel28; SKMEL28; SKMel28; SKmel28; SKML-28; SK28; AU-Mel; P-36; P36 | 15849.0 | nM | GI50 | C3510 | |
| TKC123088 | SK-MEL-5 | SK-Mel-5; SK MEL 5; SK.MEL.5; SK-MEL5; SKMel-5; SKMEL-5; SKMEL5; SKMel5; SKmel5; AA-Mel | 3981.0 | nM | GI50 | C3510 | |
| TKC123088 | UACC-62 | UACC 62; UACC.62; UACC62; University of Arizona Cell Culture-62 | 12589.0 | nM | GI50 | C3224 | |
| TKC123088 | IGROV-1 | Igrov-1; IGROV 1; IGR-OV1; IGROV1; Igrov1; IGR.OV1; IGROV; OV1/P; OV1/p; OV1-P | 11940.0 | nM | GI50 | C7979 | Orphanet_454723 |
| TKC123088 | OVCAR-4 | OVCAR 4; NIH:OVCAR-4; NIH:OVCAR4; OVCAR.4; OVCAR4; Ovcar4 | 5834.0 | nM | GI50 | C105555 | |
| TKC123088 | OVCAR-5 | OVCAR 5; NIH:OVCAR-5; OVCAR.5; OVCAR5; Ovcar5; OVCA5 | 12445.0 | nM | GI50 | C105555 | |
| TKC123088 | OVCAR-8 | OVCAR 8; NIH:OVCAR-8; OVCAR8; Ovcar8; OVCAR.8; OVCA8 | 4853.0 | nM | GI50 | C105555 | |
| TKC123088 | NCI/ADR-RES | NCI/ADR-RES; NCI.ADR.RES; NCIADR.RES; NCI/ADRRES; NCIADRRES; ADR-RES; MCF-7/ADR; MCF-7/ADR-RES; MCF-7/AdrR; MCF-7/Adr; MCF-7/adr; MCF-7ADR; MCF7-ADR; MCF7ADR; OVCAR-8/ADR; OVCAR8/ADR | 7228.0 | nM | GI50 | C105555 | |
| TKC123088 | 786-0 | 786-o; 786O; 786-0; 786.O; 786-O RCC; RCC 786-O; RCC_7860; RCC 7860; 7860; 786-0WT | 10000.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC123088 | A498 | A498 | 6081.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC123088 | ACHN | 7943.0 | nM | GI50 | C6975 | Orphanet_319298 | |
| TKC123088 | CAKI-1 | CAL 1; Centre Antoine Lacassagne-1 | 11614.0 | nM | GI50 | C3224 | |
| TKC123088 | RXF 393 | RXF393L; RXF-393 L; RXF-393; RXF 393; RXF.393; RXF393; RXF 393NL | 2512.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC123088 | SN12C | SN-12C | 10000.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC123088 | TK-10 | TK.10; TK 10; TK10 | 14791.0 | nM | GI50 | C4033 | Orphanet_319276 |
| TKC123088 | UO-31 | UO.31; UO31; U031 | 10000.0 | nM | GI50 | C9385 | Orphanet_217071 |
| TKC123088 | MDA-N | MDAN | 15849.0 | nM | GI50 | C3802 | |
| TKC123088 | T47D | 15560.0 | nM | IC50 | C4194 | ||
| TKC123088 | Hs-578T | HS 578T; Hs-578T; HS-578T; Hs_578t; Hs-578-T; HS-578-T; Hs 578.T; HS578T; Hs578T; Hs578t; HS0578T; 578T; HS578; Hs578; Homo sapiens No. 578, tumor cells | 10765.0 | nM | GI50 | C4194 | |
| TKC123088 | RAW264.7 | RAW264 | 56.0 | % | Activity | C21604 | |
| TKC123088 | HEp-2 | Hep-2; HEP-2; Hep2 (HeLa derivative); HEp-2/HeLa; Hep 2; Hep2; HEp2; HEP2; H.Ep.-2; H.Ep. #2; H.Ep. No. 2; Hep II; Human Epidermoid carcinoma #2; Human Epithelioma-2 | 16000.0 | nM | IC50 | C27677 | |
| TKC123088 | THP-1 | THP1; THP 1; THPI; THP-1(ATCC); THP-1-O; O-THP-1; Tohoku Hospital Pediatrics-1 | 20000.0 | nM | IC50 | C9163 | Orphanet_514 |
| TKC123088 | 4T1 | 4T1-A; 4T1.0; 4T1/WT | 14040.0 | nM | IC50 | C21678 | |
| TKC123088 | LLC-PK1 | LLC-PK(1); LLC-PK-1; LLC PK-1; LLc-PK1; LLC PK1; LLCPK1; Lilly Laboratories Culture-Porcine Kidney 1 | 80.0 | % | Activity | ||
| TKC123088 | MDCK | MDCK (NBL-2); NBL-2; Madin-Darby Canine Kidney; Madin Darby Canine Kidney | 20.0 | % | Activity | ||
| TKC123088 | MRC5 | MRC5; MRC 5; MRCV; MRC-V; Medical Research Council cell strain-5 | 32800.0 | nM | IC50 | ||
| TKC123088 | SiHa | Siha; SIHA | 70100.0 | nM | IC50 | C27676 | Orphanet_213767 |
| TKC123088 | HEK293 | 336200.0 | nM | IC50 |
| ID | Uniport | Pref_name | Gene name | value | unit | type |
|---|---|---|---|---|---|---|
| TKC123088 | Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | TDP1 | 3663 | nM | Potency |
| TKC123088 | Q72874 | Protease | pol | >219000 | nM | IC50 |
| TKC123088 | Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | SLCO1B3 | 39 | % | Inhibition |
| TKC123088 | Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | SLCO1B1 | 26 | % | Inhibition |
| TKC123088 | O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | IDH1 | 102 | % | Activity |
| TKC123088 | P43220 | Glucagon-like peptide 1 receptor | GLP1R | 3162 | nM | Potency |
| TKC123088 | Q03431 | Parathyroid hormone/parathyroid hormone-related peptide receptor | PTH1R | 7080 | nM | Potency |
| TKC123088 | Q04206 | Transcription factor p65 | RELA | >10000 | nM | IC50 |
| TKC123088 | Q9UBT6 | DNA polymerase kappa | POLK | 8913 | nM | Potency |
| TKC123088 | O75496 | Geminin | GMNN | 920 | nM | Potency |
| TKC123088 | Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | APOBEC3G | 8913 | nM | Potency |
| TKC123088 | P11597 | Cholesteryl ester transfer protein | CETP | 31 | % | Inhibition |
| TKC123088 | O42275 | Acetylcholinesterase | ache | -5 | % | Inhibition |
| TKC123088 | P23739 | Sucrase-isomaltase, intestinal | Si | <10 | % | Inhibition |
| TKC123088 | P81908 | Cholinesterase | BCHE | 3 | % | Inhibition |
| TKC123088 | P06746 | DNA polymerase beta | POLB | 3162 | nM | Potency |
| TKC123088 | P06746 | DNA polymerase beta | POLB | 33700 | nM | IC50 |
| TKC123088 | P06746 | DNA polymerase beta | POLB | 43600 | nM | IC50 |
| TKC123088 | P49798 | Regulator of G-protein signaling 4 | RGS4 | 37686 | nM | Potency |
| TKC123088 | Q9Y253 | DNA polymerase eta | POLH | 3981 | nM | Potency |
| TKC123088 | P47199 | Quinone oxidoreductase | Cryz | >10 | ug ml-1 | CD |
| TKC123088 | P08151 | Zinc finger protein GLI1 | GLI1 | 32000 | nM | IC50 |
| TKC123088 | P08151 | Zinc finger protein GLI1 | GLI1 | 32000 | nM | IC50 |
| TKC123088 | Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | APOBEC3F | 6310 | nM | Potency |
| TKC123088 | P51450 | Nuclear receptor ROR-gamma | Rorc | 3162 | nM | Potency |
| TKC123088 | Q13133 | Oxysterols receptor LXR-alpha | NR1H3 | 50000 | nM | EC50 |
| TKC123088 | P05771 | Protein kinase C beta type | PRKCB | >150000 | nM | IC50 |
| TKC123088 | P55055 | Oxysterols receptor LXR-beta | NR1H2 | >50000 | nM | EC50 |
| TKC123088 | P37238 | Peroxisome proliferator-activated receptor gamma | Pparg | 100000 | nM | EC50 |
| TKC123088 | P06766 | DNA polymerase beta | Polb | 6500 | nM | IC50 |
| TKC123088 | Q02156 | Protein kinase C epsilon type | PRKCE | >150000 | nM | IC50 |
| TKC123088 | Q8WZA2 | Rap guanine nucleotide exchange factor 4 | RAPGEF4 | 100000 | nM | Potency |
| TKC123088 | O60218 | Aldo-keto reductase family 1 member B10 | AKR1B10 | 2000 | nM | IC50 |
| TKC123088 | P15121 | Aldo-keto reductase family 1 member B1 | AKR1B1 | 11000 | nM | IC50 |
| TKC123088 | Q96RI1 | Bile acid receptor | NR1H4 | 0 | nM | EC50 |
| TKC123088 | P00690 | Pancreatic alpha-amylase | AMY2 | >200000 | nM | IC50 |
| TKC123088 | P0DPI0 | Botulinum neurotoxin type A | botA | 14300 | nM | Ki |
| TKC123088 | P15559 | NAD(P)H dehydrogenase [quinone] 1 | NQO1 | >20 | ug ml-1 | CD |
| TKC123088 | P02768 | Albumin | ALB | 593 | nM | Kd |
| TKC123088 | P00489 | Glycogen phosphorylase, muscle form | PYGM | 42658 | nM | IC50 |
| TKC123088 | P00489 | Glycogen phosphorylase, muscle form | PYGM | 43000 | nM | IC50 |
| TKC123088 | Q8TDU6 | G-protein coupled bile acid receptor 1 | GPBAR1 | 1040 | nM | EC50 |
| TKC123088 | Q76270 | Env polyprotein | HIV1 ENV | >100000 | nM | EC50 |
| TKC123088 | Q9GZT9 | Egl nine homolog 1 | EGLN1 | >50000 | nM | EC50 |
| TKC123088 | P27487 | Dipeptidyl peptidase 4 | DPP4 | 55820 | nM | IC50 |
| TKC123088 | Q9UBE0 | SUMO-activating enzyme subunit 1 | SAE1 | 9240 | nM | IC50 |
| TKC123088 | Q9UBE0 | SUMO-activating enzyme subunit 1 | SAE1 | 9240 | nM | IC50 |
| Uniport ID | Uniport Name | ICD-11 |
|---|---|---|
| O75874 | IDHC_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| O75874 | IDHC_HUMAN | Liver cancer [ICD-11: 2C12] |
| O75874 | IDHC_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| O75874 | IDHC_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| O75874 | IDHC_HUMAN | Acute myeloid leukaemia [ICD-11: 2A60] |
| O75874 | IDHC_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P43220 | GLP1R_HUMAN | Cardiovascular disease [ICD-11: BA00-BE2Z] |
| P43220 | GLP1R_HUMAN | Obesity [ICD-11: 5B80-5B81] |
| P43220 | GLP1R_HUMAN | Type 2 diabetes mellitus [ICD-11: 5A11] |
| P43220 | GLP1R_HUMAN | Type-1/2 diabete [ICD-11: 5A10-5A11] |
| P43220 | GLP1R_HUMAN | Acute diabete complication [ICD-11: 5A2Y] |
| P43220 | GLP1R_HUMAN | Diabetes mellitus [ICD-11: 5A10] |
| P43220 | GLP1R_HUMAN | Dyspepsia [ICD-11: MD92] |
| P43220 | GLP1R_HUMAN | Irritable bowel syndrome [ICD-11: DD91] |
| P43220 | GLP1R_HUMAN | Intracranial injury [ICD-11: NA07] |
| P43220 | GLP1R_HUMAN | Non-alcoholic fatty liver disease [ICD-11: DB92] |
| Q03431 | PTH1R_HUMAN | Low bone mass disorder [ICD-11: FB83] |
| Q03431 | PTH1R_HUMAN | Hypo-parathyroidism [ICD-11: 5A50] |
| P11597 | CETP_HUMAN | Arterial occlusive disease [ICD-11: BD40] |
| P11597 | CETP_HUMAN | Cardiovascular disease [ICD-11: BA00-BE2Z] |
| P11597 | CETP_HUMAN | Hyper-lipoproteinaemia [ICD-11: 5C80] |
| P11597 | CETP_HUMAN | Myocardial infarction [ICD-11: BA41-BA43] |
| P11597 | CETP_HUMAN | Inborn lipid metabolism error [ICD-11: 5C52] |
| P11597 | CETP_HUMAN | Chronic arterial occlusive disease [ICD-11: BD4Z] |
| P11597 | CETP_HUMAN | Dyslipidemia [ICD-11: 5C80-5C81] |
| P06746 | DPOLB_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P06746 | DPOLB_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P06746 | DPOLB_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| Q13133 | NR1H3_HUMAN | Depression [ICD-11: 6A70-6A7Z] |
| P05771 | KPCB_HUMAN | Brain cancer [ICD-11: 2A00] |
| P05771 | KPCB_HUMAN | Central nervous system disease [ICD-11: 8A04-8D87] |
| P05771 | KPCB_HUMAN | Diffuse large B-cell lymphoma [ICD-11: 2A81] |
| P05771 | KPCB_HUMAN | Lymphoma [ICD-11: 2A80-2A86] |
| P05771 | KPCB_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| P05771 | KPCB_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P05771 | KPCB_HUMAN | Transplant rejection [ICD-11: NE84] |
| P05771 | KPCB_HUMAN | Mature B-cell leukaemia [ICD-11: 2A82] |
| P05771 | KPCB_HUMAN | Rheumatoid arthritis [ICD-11: FA20] |
| P05771 | KPCB_HUMAN | Human immunodeficiency virus disease [ICD-11: 1C60-1C62] |
| P55055 | NR1H2_HUMAN | Atopic eczema [ICD-11: EA80] |
| P55055 | NR1H2_HUMAN | Depression [ICD-11: 6A70-6A7Z] |
| Q02156 | KPCE_HUMAN | Anxiety disorder [ICD-11: 6B00-6B0Z] |
| Q02156 | KPCE_HUMAN | Liver vascular disorder [ICD-11: DB98] |
| Q02156 | KPCE_HUMAN | Malaria [ICD-11: 1F40-1F45] |
| Q02156 | KPCE_HUMAN | Alzheimer disease [ICD-11: 8A20] |
| Q02156 | KPCE_HUMAN | Postoperative inflammation [ICD-11: 1A00-CA43] |
| Q02156 | KPCE_HUMAN | Human immunodeficiency virus disease [ICD-11: 1C60-1C62] |
| P15121 | ALDR_HUMAN | Neuropathy [ICD-11: 8C0Z] |
| P15121 | ALDR_HUMAN | Pain [ICD-11: MG30-MG3Z] |
| P15121 | ALDR_HUMAN | Rheumatoid arthritis [ICD-11: FA20] |
| P15121 | ALDR_HUMAN | Acute diabete complication [ICD-11: 5A2Y] |
| P15121 | ALDR_HUMAN | Thrombosis [ICD-11: DB61-GB90] |
| P15121 | ALDR_HUMAN | Cataract [ICD-11: 9B10] |
| P15121 | ALDR_HUMAN | Glaucoma [ICD-11: 9C61] |
| P15121 | ALDR_HUMAN | Schizophrenia [ICD-11: 6A20] |
| P15121 | ALDR_HUMAN | Gout [ICD-11: FA25] |
| P15121 | ALDR_HUMAN | Head and neck cancer [ICD-11: 2D42] |
| Q96RI1 | NR1H4_HUMAN | Autoimmune liver disease [ICD-11: DB96] |
| Q96RI1 | NR1H4_HUMAN | Cholelithiasis [ICD-11: DC11] |
| Q96RI1 | NR1H4_HUMAN | Insomnia [ICD-11: 7A00-7A0Z] |
| Q96RI1 | NR1H4_HUMAN | Osteoarthritis [ICD-11: FA00-FA05] |
| Q96RI1 | NR1H4_HUMAN | Breast cancer [ICD-11: 2C60-2C6Y] |
| Q96RI1 | NR1H4_HUMAN | Non-alcoholic fatty liver disease [ICD-11: DB92] |
| Q96RI1 | NR1H4_HUMAN | Chronic kidney disease [ICD-11: GB61] |
| Q96RI1 | NR1H4_HUMAN | Skeletal anomaly [ICD-11: LD24] |
| Q96RI1 | NR1H4_HUMAN | Hepatic fibrosis/cirrhosis [ICD-11: DB93] |
| Q96RI1 | NR1H4_HUMAN | Hyper-lipoproteinaemia [ICD-11: 5C80] |
| Q96RI1 | NR1H4_HUMAN | Type 2 diabetes mellitus [ICD-11: 5A11] |
| P0DPI0 | BXA1_CLOBO | Acne vulgaris [ICD-11: ED80] |
| P0DPI0 | BXA1_CLOBO | Ataxic disorder [ICD-11: 8A03] |
| P0DPI0 | BXA1_CLOBO | Clostridium difficile enterocolitis [ICD-11: 1A04] |
| P15559 | NQO1_HUMAN | Choreiform disorder [ICD-11: 8A01] |
| P15559 | NQO1_HUMAN | CNS anomalies syndrome [ICD-11: LD20] |
| P15559 | NQO1_HUMAN | Inborn energy metabolism error [ICD-11: 5C53] |
| P15559 | NQO1_HUMAN | Intellectual development disorder [ICD-11: LD90] |
| P15559 | NQO1_HUMAN | Pancreatic cancer [ICD-11: 2C10] |
| P15559 | NQO1_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P02768 | ALBU_HUMAN | Aneurysm/dissection [ICD-11: BD50] |
| P02768 | ALBU_HUMAN | Bowel habit change [ICD-11: ME05] |
| P02768 | ALBU_HUMAN | Cholelithiasis [ICD-11: DC11] |
| P02768 | ALBU_HUMAN | Inborn energy metabolism error [ICD-11: 5C53] |
| P02768 | ALBU_HUMAN | Irritable bowel syndrome [ICD-11: DD91] |
| P02768 | ALBU_HUMAN | Preprocedural examination [ICD-11: QA0B] |
| P02768 | ALBU_HUMAN | Rheumatoid arthritis [ICD-11: FA20] |
| P02768 | ALBU_HUMAN | Schizophrenia [ICD-11: 6A20] |
| P02768 | ALBU_HUMAN | Unspecific body region injury [ICD-11: ND56] |
| P02768 | ALBU_HUMAN | Coagulation defect [ICD-11: 3B10] |
| P02768 | ALBU_HUMAN | Lupus erythematosus [ICD-11: 4A40] |
| P02768 | ALBU_HUMAN | Vitamin deficiency [ICD-11: 5B55-5B5F] |
| Q8TDU6 | GPBAR_HUMAN | Type 2 diabetes mellitus [ICD-11: 5A11] |
| Q8TDU6 | GPBAR_HUMAN | Hepatic fibrosis/cirrhosis [ICD-11: DB93] |
| Q8TDU6 | GPBAR_HUMAN | Metabolic disorder [ICD-11: 5C50-5D2Z] |
| Q9GZT9 | EGLN1_HUMAN | Acute disease anaemia [ICD-11: 3A90] |
| Q9GZT9 | EGLN1_HUMAN | Urinary system disease [ICD-11: GC2Z] |
| Q9GZT9 | EGLN1_HUMAN | Solid tumour/cancer [ICD-11: 2A00-2F9Z] |
| P27487 | DPP4_HUMAN | Acute diabete complication [ICD-11: 5A2Y] |
| P27487 | DPP4_HUMAN | Chronic arterial occlusive disease [ICD-11: BD4Z] |
| P27487 | DPP4_HUMAN | Type 2 diabetes mellitus [ICD-11: 5A11] |
| P27487 | DPP4_HUMAN | Diabetes mellitus [ICD-11: 5A10] |
| P27487 | DPP4_HUMAN | Metabolic disorder [ICD-11: 5C50-5D2Z] |
| P27487 | DPP4_HUMAN | Autism spectrum disorder [ICD-11: 6A02] |
| P27487 | DPP4_HUMAN | Psoriasis [ICD-11: EA90] |
| P27487 | DPP4_HUMAN | Malignant haematopoietic neoplasm [ICD-11: 2B33] |
| P27487 | DPP4_HUMAN | Myocardial infarction [ICD-11: BA41-BA43] |
| P27487 | DPP4_HUMAN | Colon cancer [ICD-11: 2B90] |
| P27487 | DPP4_HUMAN | Lung cancer [ICD-11: 2C25] |
| P27487 | DPP4_HUMAN | Hypo-glycaemia [ICD-11: 5A41] |
| P27487 | DPP4_HUMAN | Transplanted organ/tissue [ICD-11: QB63] |