Basic Information

Terpenoid ID TKC110007
Chirality TKC206689
Cell line 0
Protein target 10
DiseaseNCIT 0
ORDO 0
ICD 23

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC110007 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 2311 nM Potency
TKC110007 Q99700 Ataxin-2 ATXN2 36 nM Potency
TKC110007 O75496 Geminin GMNN 116 nM Potency
TKC110007 Q13148 TAR DNA-binding protein 43 TARDBP 355 nM Potency
TKC110007 P0DTD1 Replicase polyprotein 1ab rep 23 % Inhibition
TKC110007 P33261 Cytochrome P450 2C19 CYP2C19 10000 nM Potency
TKC110007 P83916 Chromobox protein homolog 1 CBX1 79433 nM Potency
TKC110007 P63096 Guanine nucleotide-binding protein G GNAI1 4467 nM Potency
TKC110007 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 39811 nM Potency
TKC110007 Q16665 Hypoxia-inducible factor 1-alpha HIF1A 7943 nM Potency
TKC110007 P16473 Thyrotropin receptor TSHR 126 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
Q13148 TADBP_HUMAN Acute myeloid leukaemia [ICD-11: 2A60]
Q13148 TADBP_HUMAN Alzheimer disease [ICD-11: 8A20]
Q16665 HIF1A_HUMAN Adrenomedullary hyperfunction [ICD-11: 5A75]
Q16665 HIF1A_HUMAN Brain cancer [ICD-11: 2A00]
Q16665 HIF1A_HUMAN Lymphoma [ICD-11: 2A80-2A86]
Q16665 HIF1A_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Q16665 HIF1A_HUMAN Pulmonary hypertension [ICD-11: BB01]
P16473 TSHR_HUMAN Hypo-thyroidism [ICD-11: 5A00]
P16473 TSHR_HUMAN Thyroid cancer [ICD-11: 2D10]