Basic Information

Terpenoid ID TKC206689
Chirality TKC110007
Cell line 0
Protein target 20
DiseaseNCIT 0
ORDO 0
ICD 26

Active subnetwork


Terpenoid-cell-disease Activity Association

ID Cell Line Synonyms Value Unit Type NCIt ORDO
TKC206689 HepG2 35481.0 nM Potency C3728 Orphanet_449

Terpenoid-protein target Activity Association

ID Uniport Pref_name Gene name value unit type
TKC206689 Q16637 Survival motor neuron protein SMN1,SMN2 19953 nM Potency
TKC206689 Q16637 Survival motor neuron protein SMN1,SMN2 19953 nM Potency
TKC206689 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 TDP1 10593 nM Potency
TKC206689 P08684 Cytochrome P450 3A4 CYP3A4 25 nM Potency
TKC206689 Q16236 Nuclear factor erythroid 2-related factor 2 NFE2L2 1636 nM Potency
TKC206689 O75496 Geminin GMNN 5 nM Potency
TKC206689 O89049 Thioredoxin reductase 1, cytoplasmic Txnrd1 42284 nM Potency
TKC206689 P0DTD1 Replicase polyprotein 1ab rep 1 % Inhibition
TKC206689 P83916 Chromobox protein homolog 1 CBX1 31623 nM Potency
TKC206689 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 EHMT2 10000 nM Potency
TKC206689 Q96QE3 ATPase family AAA domain-containing protein 5 ATAD5 29081 nM Potency
TKC206689 P54132 Bloom syndrome protein BLM 3 nM Potency
TKC206689 Q01453 Peripheral myelin protein 22 PMP22 95283 nM Potency
TKC206689 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 25119 nM Potency
TKC206689 Q9F4F7 4'-phosphopantetheinyl transferase ffp ffp 10000 nM Potency
TKC206689 Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B BAZ2B 708 nM Potency
TKC206689 P02545 Prelamin-A/C LMNA 5 nM Potency
TKC206689 P08482 Muscarinic acetylcholine receptor M1 Chrm1 3981 nM Potency
TKC206689 P15289 Arylsulfatase A ARSA 8492 nM Potency
TKC206689 O35627 Nuclear receptor subfamily 1 group I member 3 Nr1i3 88 % Remaining activity
TKC206689 P04278 Sex hormone-binding globulin SHBG 36 nM Kd
TKC206689 P08185 Corticosteroid-binding globulin SERPINA6 13 nM Ki
TKC206689 P56937 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 HSD17B7 0 % Inhibition
TKC206689 P0A6C1 Endonuclease 4 nfo 50119 nM Potency

Protein target-disease Activity Association

Uniport ID Uniport Name ICD-11
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
Q16637 SMN_HUMAN Muscular atrophy [ICD-11: 8B61]
P08684 CP3A4_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P08684 CP3A4_HUMAN Atopic eczema [ICD-11: EA80]
P08684 CP3A4_HUMAN Anxiety disorder [ICD-11: 6B00-6B0Z]
Q16236 NF2L2_HUMAN Ataxic disorder [ICD-11: 8A03]
Q16236 NF2L2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q16236 NF2L2_HUMAN Glaucoma [ICD-11: 9C61]
Q16236 NF2L2_HUMAN Lung cancer [ICD-11: 2C25]
Q16236 NF2L2_HUMAN Macular degeneration [ICD-11: 9B75]
Q16236 NF2L2_HUMAN Melanoma [ICD-11: 2C30]
Q16236 NF2L2_HUMAN Mental/behavioural/neurodevelopmental disorder [ICD-11: 6E20-6E8Z]
Q16236 NF2L2_HUMAN Pulmonary hypertension [ICD-11: BB01]
Q16236 NF2L2_HUMAN Subarachnoid haemorrhage [ICD-11: 8B01]
Q16236 NF2L2_HUMAN Urinary system clinical sympton [ICD-11: MF8Y]
Q16236 NF2L2_HUMAN Non-alcoholic fatty liver disease [ICD-11: DB92]
Q16236 NF2L2_HUMAN Alpha-1-antitrypsin deficiency [ICD-11: 5C5A]
Q16236 NF2L2_HUMAN Motor neuron disease [ICD-11: 8B60]
Q16236 NF2L2_HUMAN Multiple sclerosis [ICD-11: 8A40]
Q96KQ7 EHMT2_HUMAN Breast cancer [ICD-11: 2C60-2C6Y]
Q96KQ7 EHMT2_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
Q96KQ7 EHMT2_HUMAN Solid tumour/cancer [ICD-11: 2A00-2F9Z]
P15289 ARSA_HUMAN Lysosomal disease [ICD-11: 5C56]
P08185 CBG_HUMAN Asthma [ICD-11: CA23]
P08185 CBG_HUMAN Postoperative inflammation [ICD-11: 1A00-CA43]
P08185 CBG_HUMAN Respiratory system disease [ICD-11: CB40-CB7Z]
P08185 CBG_HUMAN Retinopathy [ICD-11: 9B71]